The early effects of stavudine compared with tenofovir on adipocyte gene expression, mitochondrial DNA copy number and metabolic parameters in South African HIV-infected patients: A randomized trial

HIV Medicine

Volumn 14, Issue 4, 2013, Pages 217-225

  Menezes, C N ^a,b,h   Duarte, R ^c,h   Dickens, C ^c,h   Dix Peek, T ^c,h   Van Amsterdam, D ^b   John, M A ^d,h   Ive, P ^b   Maskew, M ^e,f   Macphail, P ^e   Fox, M P ^f,g,h   Raal, F ^c,h   Sanne, I ^b,e,h   Crowther, N J ^d,h  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b HELEN JOSEPH HOSPITAL   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d NATIONAL HEALTH LABORATORY SERVICE   (South Africa)

^e RIGHT TO CARE   (South Africa)

^f UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^g BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^h UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Gene expression; Insulin resistance; Lipids; Mitochondria; Stavudine; Tenofovir

Indexed keywords

CYTOCHROME B; EFAVIRENZ; GLUCOSE; LAMIVUDINE; LIPID; MITOCHONDRIAL DNA; NUCLEAR RESPIRATORY FACTOR 1; STAVUDINE; TENOFOVIR;

ADIPOCYTE; ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE DOSAGE; GENE EXPRESSION; GLUCOSE METABOLISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SOUTH AFRICA; SUBCUTANEOUS FAT;

ADENINE; ADIPOCYTES; ADULT; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BIOLOGICAL MARKERS; DNA COPY NUMBER VARIATIONS; DNA, MITOCHONDRIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION PROFILING; GLUCOSE; HIV INFECTIONS; HUMANS; INFLAMMATION; LIPID METABOLISM; MALE; MIDDLE AGED; ORGANOPHOSPHONATES; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE INHIBITORS; SOUTH AFRICA; STAVUDINE;

EID: 84874543425     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2012.01054.x     Document Type: Article

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