Hydrophilic interaction chromatography with aerosol-based detectors (ELSD, CAD, NQAD) for polar compounds lacking a UV chromophore in an intravenous formulation

Journal of Pharmaceutical and Biomedical Analysis

Volumn 78-79, Issue , 2013, Pages 14-18

  Cintrón, José M ^a   Risley, Donald S ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

( ) (1R; 4S; 5S; 6S) 4 Amino 2 sulfonylbicyclo 3.1.0 hexane 4,6 dicarboxylic acid; Aerosol; HILIC; Mannitol; Polar

Indexed keywords

4 AMINO 2 THIABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID 2,2 DIOXIDE; ACETONITRILE; BUFFER; MANNITOL; TRIFLUOROACETIC ACID;

ACCURACY; AEROSOL; ANALYTICAL EQUIPMENT; ARTICLE; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CORONA AEROSOL DETECTOR; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIGHT SCATTERING DETECTOR; LIMIT OF DETECTION; MEASUREMENT REPEATABILITY; NANO QUANTITY ANALYTE DETECTOR; PH; PRIORITY JOURNAL; REPRODUCIBILITY;

AEROSOLS; CHROMATOGRAPHY, LIQUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIMIT OF DETECTION; REPRODUCIBILITY OF RESULTS; ULTRAVIOLET RAYS;

EID: 84874542136     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.01.022     Document Type: Article

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