-
1
-
-
0025014962
-
Physiological Barriers to Delivery of Monoclonal Antibodies and Other Macromolecules in Tumors
-
Jain RK, (1990) Physiological Barriers to Delivery of Monoclonal Antibodies and Other Macromolecules in Tumors. Cancer Res (Suppl.) 50: 814-819.
-
(1990)
Cancer Res (Suppl.)
, vol.50
, pp. 814-819
-
-
Jain, R.K.1
-
2
-
-
0035816177
-
Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function
-
Jain RK, (2001) Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function. J Control Release 74: 7-25.
-
(2001)
J Control Release
, vol.74
, pp. 7-25
-
-
Jain, R.K.1
-
3
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain RK, (2011) Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy. Nature Med 7: 987-989.
-
(2011)
Nature Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
4
-
-
1642362625
-
Drug delivery systems: entering the mainstream
-
Allen TM, Cullis PR, (2004) Drug delivery systems: entering the mainstream. Science 303: 1818-22.
-
(2004)
Science
, vol.303
, pp. 1818-1822
-
-
Allen, T.M.1
Cullis, P.R.2
-
5
-
-
14644439267
-
Cancer nanotechnology: opportunities and challenges
-
Ferrari M, (2005) Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 5: 161-171.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
-
6
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, et al. (2007) Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2: 751-760.
-
(2007)
Nat Nanotechnol
, vol.2
, pp. 751-760
-
-
Peer, D.1
Karp, J.M.2
Hong, S.3
Farokhzad, O.C.4
Margalit, R.5
-
7
-
-
0032758610
-
Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors
-
Drummond DC, Meyer O, Hong K, Kirpotin DB, Papahadjopoulos D, (1999) Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 51: 691-743.
-
(1999)
Pharmacol Rev
, vol.51
, pp. 691-743
-
-
Drummond, D.C.1
Meyer, O.2
Hong, K.3
Kirpotin, D.B.4
Papahadjopoulos, D.5
-
8
-
-
14144250911
-
Recent advances with liposomes as pharmaceutical carriers
-
Torchilin VP, (2005) Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 4: 145-160.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 145-160
-
-
Torchilin, V.P.1
-
9
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y, Maeda H, (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46(12 Pt 1): 6387-6392.
-
(1986)
Cancer Res
, vol.46
, Issue.12 Pt 1
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
10
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
-
Maeda H, Wu J, Sawa T, Matsumura Y, Hori K, (2000) Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 65: 271-284.
-
(2000)
J Control Release
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
12
-
-
0025784978
-
Vascular endothelial cell differentiation: organ-specificity and selective affinities as the basis for developing anti-cancer strategies
-
Auerbach R, (1991) Vascular endothelial cell differentiation: organ-specificity and selective affinities as the basis for developing anti-cancer strategies. Int J Radiat Biol 60: 1-10.
-
(1991)
Int J Radiat Biol
, vol.60
, pp. 1-10
-
-
Auerbach, R.1
-
13
-
-
33751540859
-
Display technologies: application for the discovery of drug and gene delivery agents
-
Sergeeva A, Kolonin MG, Molldrem JJ, Pasqualini R, Arap W, (2006) Display technologies: application for the discovery of drug and gene delivery agents. Adv Drug Deliv Rev 58: 1622-1654.
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 1622-1654
-
-
Sergeeva, A.1
Kolonin, M.G.2
Molldrem, J.J.3
Pasqualini, R.4
Arap, W.5
-
14
-
-
70449776165
-
Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows
-
Lee SY, Ferrari M, Decuzzi P, (2009) Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows. Nanotechnology 20: 495101.
-
(2009)
Nanotechnology
, vol.20
, pp. 495101
-
-
Lee, S.Y.1
Ferrari, M.2
Decuzzi, P.3
-
15
-
-
33746092084
-
The adhesive strength of non-spherical particles mediated by specific interactions
-
Decuzzi P, Ferrari M, (2006) The adhesive strength of non-spherical particles mediated by specific interactions. Biomaterials 27: 5307-5314.
-
(2006)
Biomaterials
, vol.27
, pp. 5307-5314
-
-
Decuzzi, P.1
Ferrari, M.2
-
16
-
-
57749207052
-
Intravascular delivery of particulate systems: does geometry really matter?
-
Decuzzi P, Pasqualini R, Arap W, Ferrari M, (2009) Intravascular delivery of particulate systems: does geometry really matter? Pharm Res 26: 235-243.
-
(2009)
Pharm Res
, vol.26
, pp. 235-243
-
-
Decuzzi, P.1
Pasqualini, R.2
Arap, W.3
Ferrari, M.4
-
17
-
-
84870640641
-
Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors
-
van de Ven AL, Wu M, Lowengrub J, McDougall SR, Chaplain MA, et al. (2012) Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors. AIP Adv. 2: 11208.
-
(2012)
AIP Adv
, vol.2
, pp. 11208
-
-
van de Ven, A.L.1
Wu, M.2
Lowengrub, J.3
McDougall, S.R.4
Chaplain, M.A.5
-
18
-
-
84857914530
-
Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution
-
van de Ven A, Kim P, Haley O, Fakhoury J, Adriani G, et al. (2012) Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution. J Control Release 158: 148-155.
-
(2012)
J Control Release
, vol.158
, pp. 148-155
-
-
van de Ven, A.1
Kim, P.2
Haley, O.3
Fakhoury, J.4
Adriani, G.5
-
19
-
-
84872477242
-
The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems
-
Wu M, Frieboes HB, McDougall S, Chaplain MA, Cristini V, et al. (2013) The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems. J Theor Biol 320: 131-151.
-
(2013)
J Theor Biol
, vol.320
, pp. 131-151
-
-
Wu, M.1
Frieboes, H.B.2
McDougall, S.3
Chaplain, M.A.4
Cristini, V.5
-
20
-
-
58349120594
-
Multiscale Modeling and Simulation of Vascular Tumour Growth
-
Macklin P, McDougall S, Anderson ARA, Chaplain MAJ, Cristini V, et al. (2009) Multiscale Modeling and Simulation of Vascular Tumour Growth. J Math Biol 58: 765-798.
-
(2009)
J Math Biol
, vol.58
, pp. 765-798
-
-
Macklin, P.1
McDougall, S.2
Anderson, A.R.A.3
Chaplain, M.A.J.4
Cristini, V.5
-
21
-
-
34547807824
-
Computer simulation of glioma growth and morphology
-
Frieboes HB, Lowengrub JS, Wise SM, Zheng X, Bearer EL, et al. (2007) Computer simulation of glioma growth and morphology. NeuroImage 37: S59-S70.
-
(2007)
NeuroImage
, vol.37
-
-
Frieboes, H.B.1
Lowengrub, J.S.2
Wise, S.M.3
Zheng, X.4
Bearer, E.L.5
-
22
-
-
77952954625
-
Three-dimensional multispecies tumor growth-II: Tumor invasion and angiogenesis
-
Frieboes HB, Jin F, Chuang YL, Wise SM, Lowengrub JS, et al. (2010) Three-dimensional multispecies tumor growth-II: Tumor invasion and angiogenesis. J Theor Biol 264: 1254-1278.
-
(2010)
J Theor Biol
, vol.264
, pp. 1254-1278
-
-
Frieboes, H.B.1
Jin, F.2
Chuang, Y.L.3
Wise, S.M.4
Lowengrub, J.S.5
-
23
-
-
78751499525
-
Physical oncology: a bench-to-bedside quantitative and predictive approach
-
Frieboes HB, Chaplain MA, Thompson AM, Bearer EL, Lowengrub JS, et al. (2011) Physical oncology: a bench-to-bedside quantitative and predictive approach.Cancer Res. 71: 298-302.
-
(2011)
Cancer Res
, vol.71
, pp. 298-302
-
-
Frieboes, H.B.1
Chaplain, M.A.2
Thompson, A.M.3
Bearer, E.L.4
Lowengrub, J.S.5
-
24
-
-
84862833470
-
Optimizing particle size for targeting diseased microvasculature: from experiments to artificial neural networks
-
Boso DP, Lee SY, Ferrari M, Schrefler BA, Decuzzi P, (2011) Optimizing particle size for targeting diseased microvasculature: from experiments to artificial neural networks. Int J Nanomedicine. 6: 1517-1526.
-
(2011)
Int J Nanomedicine
, vol.6
, pp. 1517-1526
-
-
Boso, D.P.1
Lee, S.Y.2
Ferrari, M.3
Schrefler, B.A.4
Decuzzi, P.5
-
25
-
-
0141731298
-
Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging
-
Winter PM, Caruthers SD, Kassner A, Harris TD, Chinen LK, et al. (2003) Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging. Cancer Res 63: 5838-5843.
-
(2003)
Cancer Res
, vol.63
, pp. 5838-5843
-
-
Winter, P.M.1
Caruthers, S.D.2
Kassner, A.3
Harris, T.D.4
Chinen, L.K.5
-
26
-
-
54549120584
-
Real-time intravital imaging of RGD-quantum dot binding to luminal endothelium in mouse tumor neovasculature
-
Smith BR, Cheng Z, De A, Koh AL, Sinclair R, et al. (2008) Real-time intravital imaging of RGD-quantum dot binding to luminal endothelium in mouse tumor neovasculature. Nano Lett 8: 2599-2606.
-
(2008)
Nano Lett
, vol.8
, pp. 2599-2606
-
-
Smith, B.R.1
Cheng, Z.2
De, A.3
Koh, A.L.4
Sinclair, R.5
-
28
-
-
32944454936
-
An Integrated Computational/Experimental Model of Tumor Invasion
-
Frieboes HB, Zheng X, Sun CH, Tromberg B, Gatenby R, et al. (2006) An Integrated Computational/Experimental Model of Tumor Invasion. Cancer Res 66: 1597-1604.
-
(2006)
Cancer Res
, vol.66
, pp. 1597-1604
-
-
Frieboes, H.B.1
Zheng, X.2
Sun, C.H.3
Tromberg, B.4
Gatenby, R.5
-
29
-
-
0032170064
-
Continuous and discrete mathematical models of tumor-induced angiogenesis
-
Anderson AR, Chaplain MA, (1998) Continuous and discrete mathematical models of tumor-induced angiogenesis. Bull Math Biol 60: 857-899.
-
(1998)
Bull Math Biol
, vol.60
, pp. 857-899
-
-
Anderson, A.R.1
Chaplain, M.A.2
-
30
-
-
33745918670
-
Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications andtherapeutic targeting strategies
-
McDougall SR, Anderson ARA, Chaplain MAJ, (2006) Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications andtherapeutic targeting strategies. J Theor Biol 241: 564-589.
-
(2006)
J Theor Biol
, vol.241
, pp. 564-589
-
-
McDougall, S.R.1
Anderson, A.R.A.2
Chaplain, M.A.J.3
-
31
-
-
66249110346
-
Prediction of drug response in breast cancer using integrative experimental/computational modeling
-
Frieboes HB, Edgerton ME, Fruehauf JP, Rose FRAJ, Worrall LK, et al. (2009) Prediction of drug response in breast cancer using integrative experimental/computational modeling. Cancer Res 69: 4484-4492.
-
(2009)
Cancer Res
, vol.69
, pp. 4484-4492
-
-
Frieboes, H.B.1
Edgerton, M.E.2
Fruehauf, J.P.3
Rose, F.R.A.J.4
Worrall, L.K.5
-
32
-
-
58349108845
-
Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation
-
Sinek JP, Sanga S, Zheng X, Frieboes HB, Ferrari M, et al. (2009) Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation. J Math Biol 58: 485-510.
-
(2009)
J Math Biol
, vol.58
, pp. 485-510
-
-
Sinek, J.P.1
Sanga, S.2
Zheng, X.3
Frieboes, H.B.4
Ferrari, M.5
-
33
-
-
78650816134
-
Predictions of tumour morphological stability and evaluation against experimental observations
-
Pham K, Frieboes HB, Cristini V, Lowengrub J, (2011) Predictions of tumour morphological stability and evaluation against experimental observations. J R Soc Interface 8: 16-29.
-
(2011)
J R Soc Interface
, vol.8
, pp. 16-29
-
-
Pham, K.1
Frieboes, H.B.2
Cristini, V.3
Lowengrub, J.4
-
34
-
-
0003293418
-
On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies
-
Gompertz B, (1825) On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies. Philos Trans R Soc Lond 115: 513-585.
-
(1825)
Philos Trans R Soc Lond
, vol.115
, pp. 513-585
-
-
Gompertz, B.1
-
35
-
-
0002587798
-
The Gompertz curve as a growth curve
-
Winsor CP, (1932) The Gompertz curve as a growth curve. Proc Natl Acad Sci 18: 1-8.
-
(1932)
Proc Natl Acad Sci
, vol.18
, pp. 1-8
-
-
Winsor, C.P.1
-
36
-
-
84966166281
-
Dynamics of tumor growth
-
Laird AK, (1964) Dynamics of tumor growth. Br J Cancer 18: 490-502.
-
(1964)
Br J Cancer
, vol.18
, pp. 490-502
-
-
Laird, A.K.1
-
37
-
-
0031852651
-
Structural adaptation and stability of microvascular networks: theory and simulations
-
Pries AR, Secomb TW, Gaehtgens P, (1998) Structural adaptation and stability of microvascular networks: theory and simulations. Am J Physiol Heart Circ Physiol 275: H349-H360.
-
(1998)
Am J Physiol Heart Circ Physiol
, vol.275
-
-
Pries, A.R.1
Secomb, T.W.2
Gaehtgens, P.3
-
38
-
-
0036664608
-
Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies
-
McDougall SR, Anderson ARA, Chaplain MAJ, Sherratt JA, (2002) Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies. Bull Math Biol 64: 673-702.
-
(2002)
Bull Math Biol
, vol.64
, pp. 673-702
-
-
McDougall, S.R.1
Anderson, A.R.A.2
Chaplain, M.A.J.3
Sherratt, J.A.4
-
40
-
-
23244446626
-
Effect of microvillus deformability on leukocyte adhesion explored using adhesive dynamics simulations
-
Caputo KE, Hammer DA, (2005) Effect of microvillus deformability on leukocyte adhesion explored using adhesive dynamics simulations. Biophys J 89: 187-200.
-
(2005)
Biophys J
, vol.89
, pp. 187-200
-
-
Caputo, K.E.1
Hammer, D.A.2
|