31P MR spectroscopy to evaluate the efficacy of hepatic artery embolization in the treatment of neuroendocrine liver metastases

Acta Radiologica

Volumn 53, Issue 10, 2012, Pages 1118-1126

  Ljungberg, Maria ^a,b   Westberg, Gunnel ^a   Vikhoff Baaz, Barbro ^a,b   Starck, Göran ^a,b   Wängberg, Bo ^a   Ekholm, Sven ^a   Ahlman, Håkan ^a   Forssell Aronsson, Eva ^a,b  

^a SAHLGRENSKA ACADEMY AT UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

31P; Gastrointestinal neuroendocrine (NE) tumors; Hepatic arterial embolization (HAE); Magnetic resonance spectroscopy (MRS); Treatment efficacy

Indexed keywords

ARTERIAL EMBOLIZATION; EMBOLIZATION; HEPATIC ARTERY; IF THERE ARE; IN-VIVO; INTRINSIC PROPERTY; LIVER METASTASIS; LYMPH NODE; MAGNETIC RESONANCE SPECTROSCOPIES (MRS); MEDICAL TREATMENT; METABOLIC CHANGES; METASTATIC DISEASE; MR SPECTROSCOPY; RELIABLE METHODS; SIGNIFICANT DIFFERENCES; SPECTRAL PATTERNS; THERAPEUTIC EFFICACY; TREATMENT EFFICACY; TUMOR TISSUES;

CELL MEMBRANES; CYTOLOGY; ENERGY UTILIZATION; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; TUMORS;

ENZYME INHIBITION;

ADULT; AGED; ARTICLE; ARTIFICIAL EMBOLISM; FEMALE; GASTROINTESTINAL TUMOR; HEPATIC ARTERY; HUMAN; LIVER; LIVER TUMOR; MALE; METASTASIS; METHODOLOGY; MIDDLE AGED; NEUROENDOCRINE TUMOR; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; TREATMENT OUTCOME;

ADULT; AGED; EMBOLIZATION, THERAPEUTIC; FEMALE; GASTROINTESTINAL NEOPLASMS; HEPATIC ARTERY; HUMANS; LIVER; LIVER NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; NEUROENDOCRINE TUMORS; TREATMENT OUTCOME;

MLCS; MLOWN;

EID: 84874513915     PISSN: 02841851     EISSN: 16000455     Source Type: Journal    
DOI: 10.1258/ar.2012.120050     Document Type: Article

References (24)

1. Williams ED, Sandler M. The classification of carcinoid tumours. Lancet 1963;2: 238-9
2. Plockinger U, Rindi G, Arnold R, et al. Guidelines for the diagnosis and treatment of neuroendocrine gastrointestinal tumours. A consensus statement on behalf of the European Neuroendocrine Tumour Society (ENETS). Neuroendocrinology 2004;80: 394-424
3. Swärd C, Johanson V, Nieveen van Dijkum E, et al. Prolonged survival after hepatic artery embolization in patients with midgut carcinoid syndrome. Br J Surg 2009;96: 517-21
4. Wängberg B, Westberg G, Tylen U, et al. Survival of patients with disseminated midgut carcinoid tumors after aggressive tumor reduction. World J Surg 1996;20: 892-9
5. Wängberg B, Ahlman H, Tylen U, et al. Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome. Br J Cancer 1995;71: 617-8
6. Hellstrand K, Hermodsson S. Role of serotonin in the regulation of human natural killer cell cytotoxicity. J Immunol 1987;139: 869-75
7. Solga SF, Horska A, Clark JM, et al. Hepatic 31P magnetic resonance spectroscopy: a hepatologist's user guide. Liver Int 2005;25: 490-500
8. Bates TE, Williams SR, Gadian DG. Phosphodiesters in the liver: the effect of field strength on the 31P signal. Magn Reson Med 1989;12: 145-50
9. Cox IJ, Menon DK, Sargentoni J, et al. Phosphorus-31 magnetic resonance spectroscopy of the human liver using chemical shift imaging techniques. J Hepatol 1992;14: 265-75
10. Bell JD, Bhakoo KK. Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours. NMR Biomed 1998;11: 354-9
11. Cox IJ, Bryant DJ, Collins AG, et al. Four-dimensional chemical shift MR imaging of phosphorus metabolites of normal and diseased human liver. J Comput Assist Tomogr 1988;12: 369-76
12. Cox IJ, Bell JD, Peden CJ, et al. In vivo and in vitro 31P magnetic resonance spectroscopy of focal hepatic malignancies. NMR Biomed 1992;5: 114-20
13. Schilling A, Gewiese B, Berger G, et al. Liver tumors: follow-up with P-31 MR spectroscopy after local chemotherapy and chemoembolization. Radiology 1992;182: 887-90
14. Meyerhoff DJ, Karczmar GS, Valone F, et al. Hepatic cancers and their response to chemoembolization therapy. Quantitative image-guided 31P magnetic resonance spectroscopy. Invest Radiol 1992;27: 456-64
15. Ordidge RJ, Connelly A, Lohman JAB. Image-selected in vivo spectroscopy (ISIS) - A new technique for spatially selective NMR-spectroscopy. J Magn Reson 1986;66: 283-94
16. Ljungberg M, Starck G, Vikhoff-Baaz B, et al. Signal profile measurements of single- and double-volume acquisitions with image-selected in vivo spectroscopy for 31P magnetic resonance spectroscopy. Magn Reson Imaging 1998;16: 829-37
17. van der Veen JW, de Beer R, Luyten PR, et al. Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge. Magn Reson Med 1988;6: 92-8
18. Noren B, Lundberg P, Ressner M, et al. Absolute quantification of human liver metabolite concentrations by localized in vivo 31P NMR spectroscopy in diffuse liver disease. Eur Radiol 2005;15: 148-57
19. Robitaille PML, Robitaille PA, Brown GG, et al. An Analysis of the pH-Dependent Chemical-Shift Behavior of Phosphorus-Containing Metabolites. J Magn Reson 1991;92: 73-84
20. Brinkmann G, Melchert UH, Muhle C, et al. Influence of different fasting periods on P-31-MR-spectroscopy of the liver in normals and patients with liver metastases. Eur Radiol 1996;6: 62-5
21. Bell JD, Cox IJ, Sargentoni J, et al. A 31P and 1H-NMR investigation in vitro of normal and abnormal human liver. Biochim Biophys Acta 1993;1225: 71-7
22. Dagnelie PC, Sijens PE, Kraus DJ, et al. Abnormal liver metabolism in cancer patients detected by (31)P MR spectroscopy. NMR Biomed 1999;12: 535-44
23. NegendankW. Studies of human tumors by MRS: a review. NMR Biomed 1992;5: 303-24
24. Nilsson O, Arvidsson Y, Johanson V, et al. New medical strategies for midgut carcinoids. Anticancer Agents Med Chem 2010;10: 250-69