A comparison of therapies for the treatment of drug cues: Counterconditioning vs. extinction in male rats

Experimental and Clinical Psychopharmacology

Volumn 20, Issue 6, 2012, Pages 447-453

  Tunstall, Brendan J ^a   Verendeev, Andrey ^a   Kearns, David N ^a  

^a AMERICAN UNIVERSITY   (United States)

Author keywords

Cocaine self administration; Counterconditioning; Cues; Extinction; Rat

Indexed keywords

COCAINE;

ANIMAL EXPERIMENT; ARTICLE; CATHETER; COMPARATIVE STUDY; CONDITIONING; CONTROLLED STUDY; DRUG SEEKING BEHAVIOR; FOOTSHOCK; LIGHT; LIGHT DARK CYCLE; MALE; NONHUMAN; RAT; REINFORCEMENT; STIMULUS; STIMULUS RESPONSE;

ANIMALS; CONDITIONING, OPERANT; EXTINCTION, PSYCHOLOGICAL; MALE; MORPHINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84874474690     PISSN: 10641297     EISSN: 19362293     Source Type: Journal    
DOI: 10.1037/a0030593     Document Type: Article

References (40)

1. Annau, Z., & Kamin, L. J. (1961). The conditioned emotional response as a function of intensity of the US. Journal of Comparative and Physiological Psychology, 54, 428-432. doi:10.1037/h0042199
2. Benjamini, Y., & Hochberg, Y. (1995). Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society, 57B, 289-300.
3. Bordnick, P. S., Elkins, R. L., Orr, T. E., Walters, P., & Thyer, B. A. (2004). Evaluating the relative effectiveness of three aversion therapies designed to reduce craving among cocaine abusers. Behavioral Interventions, 19, 1-24. doi:10.1002/bin.146
4. Bouton, M. E., & Peck, C. A. (1992). Spontaneous recovery in crossmotivational transfer (counterconditioning). Animal Learning & Behavior, 20, 313-321. doi:10.3758/BF03197954
5. Brethower, D. M., & Reynolds, G. S. (1962). A facilitative effect of punishment on unpunished behavior. Journal of the Experimental Analysis of Behavior, 5, 191-199. doi:10.1901/jeab.1962.5-191
6. Brooks, D. C., Hale, B., Nelson, J. B., & Bouton, M. E. (1995). Reinstatement after counterconditioning. Animal Learning & Behavior, 23, 383- 390. doi:10.3758/BF03198938
7. Childress, A. R., Mozley, P. D., McElgin, W., Fitzgerald, J., Reivich, M., & O'Brien, C. P. (1999). Limbic activation during cue-induced cocaine craving. The American Journal of Psychiatry, 156, 11-18.
8. Conklin, C. A., & Tiffany, S. T. (2002). Applying extinction research and theory to cue-exposure addiction treatments. Addiction, 97, 155-167. doi:10.1046/j.1360-0443.2002.00014.x
9. Drummond, D. S., Tiffany, S. T., Glautier, S., & Remington, B. (1995). Addictive Behaviour: Cue Exposure Theory and Practice. West Sussex, England: Wiley.
10. Frawley, P. J., & Smith, J. W. (1990). Chemical aversion therapy in the treatment of cocaine dependence as part of a multimodal treatment program: Treatment outcome. Journal of Substance Abuse Treatment, 7, 21-29. doi:10.1016/0740-5472(90)90033-M
11. Frawley, P. J., & Smith, J. W. (1992). One-year follow-up after multimodal inpatient treatment for cocaine and methamphetamine dependencies. Journal of Substance Abuse Treatment, 9, 271-286. doi:10.1016/07405472(92)90020-O
12. Grüsser, S., Wrase, J., Klein, S., Hermann, D., Smolka, M. N., Ruf, M., Heinz, A. (2004). Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology, 175, 296-302. doi:10.1007/s00213004-1828-4
13. Janak, P. H., Bowers, M. S., & Corbit, L. H. (2012). Compound stimulus presentation and the norepinephrine reuptake inhibitor atomoxetine enhance long-term extinction of cocaine-seeking behavior. Neuropsychopharmacology, 37, 975-985. doi:10.1038/npp.2011.281
14. Kearns, D. N., Tunstall, B. J., & Weiss, S. J. (2012). Deepened extinction of cocaine cues. Drug and Alcohol Dependence, 124, 283-287. doi:10.1016/j.drugalcdep.2012.01.024
15. Kearns, D. N., & Weiss, S. J. (2012). Extinguished cocaine cues increase drug seeking when presented simultaneously with a non-extinguished cocaine cue. Drug and Alcohol Dependence, 121, 140-147. doi:10.1016/j.drugalcdep.2011.08.022
16. Kearns, D. N., Weiss, S. J., & Panlilio, L. V. (2002). Conditioned suppression of behavior maintained by cocaine self-administration. Drug and Alcohol Dependence, 65, 253-261. doi:10.1016/S0376-8716(01)00167-3
17. Kearns, D. N., Weiss, S. J., Schindler, C. W., & Panlilio, L. V. (2005). Conditioned inhibition of cocaine seeking in rats. Journal of Experimental Psychology: Animal Behavior Processes, 31, 247-253. doi:10.1037/0097-7403.31.2.247\
18. Kerkhof, I., Vansteenwegen, D., Baeyens, F., & Hermans, D. (2011). Counterconditioning: An effective technique for changing conditioned preferences. Experimental Psychology, 58, 31-38. doi:10.1027/1618-3169/a000063
19. Kosten, T. R., Scanley, B. E., Tucker, K. A., Oliveto, A., Prince, C., Sinha, R.,...Wexler, B. E. (2006). Cue-induced brain activity changes and relapse in cocaine-dependent subjects. Neuropsychopharmacology, 31, 644-650. doi:10.1038/sj.npp.1300851
20. Loeber, S., Croissant, B., Heinz, A., Mann, K., & Flor, H. (2006). Cue exposure in the treatment of alcohol dependence: Effects on drinking outcome, craving and self-efficacy. British Journal of Clinical Psychology, 45, 515-529. doi:10.1348/014466505X82586
21. Lovibond, P. F., & Dickinson, A. (1982). Counterconditioning of appetitive and defensive CRs in rabbits. The Quarterly Journal of Experimental Psychology B: Comparative and Physiological Psychology, 34, 115-126.
22. Marissen, M. A., Franken, I. H., Blanken, P., van den Brink, W., & Hendriks, V. M. (2007). Cue exposure therapy for the treatment of opiate addiction: Results of a randomized controlled clinical trial. Psychotherapy and Psychosomatics, 76, 97-105. doi:10.1159/000097968
23. National Academy of Sciences. (1996). Guide for the care and use of laboratory animals. Washington, DC: National Academy Press.
24. Panlilio, L. V., Weiss, S. J., & Schindler, C. W. (1996). Cocaine selfadministration increased by compounding discriminative stimuli. Psychopharmacology, 125, 202-208. doi:10.1007/BF02247329
25. Peck, C. A., & Bouton, M. E. (1990). Context and performance in aversiveto-appetitive and appetitive-to-aversive transfer. Learning and Motivation, 21, 1-31. doi:10.1016/0023-9690(90)90002-6
26. Rescorla, R. A. (2006). Deepened extinction from compound stimulus presentation. Journal of Experimental Psychology: Animal Behavior Processes, 32, 135-144. doi:10.1037/0097-7403.32.2.135
27. Rohsenow, D. J., Monti, P. M., Rubonis, A. V., Gulliver, S. B., Colby, S. M., Binkoff, J. A., & Abrams, D. B. (2001). Cue exposure with coping skills training and communication skills training for alcohol dependence: 6- and 12-month outcomes. Addiction, 96, 1161-1174. doi:10.1046/j .1360-0443.2001.96811619.x
28. Sinha, R., & Li, C. S. (2007). Imaging stress- and cue-induced drug and alcohol craving: Association with relapse and clinical implications. Drug and Alcohol Review, 26, 25-31. doi:10.1080/09595230601036960
29. Smith, J. W., & Frawley, P. J. (1993). Treatment outcome of 600 chemically dependent patients treated in a multimodal inpatient program including aversion therapy and pentothal interviews. Journal of Substance Abuse Treatment, 10, 359-369. doi:10.1016/07405472(93)90021-S
30. Vanderschuren, L. J. M. J., & Everitt, B. J. (2004). Drug seeking becomes compulsive after prolonged cocaine self-administration. Science, 305, 1017-1019. doi:10.1126/science.1098975
31. Van Gucht, D., Baeyens, F., Vansteenwegen, D., Hermans, D., & Beckers, T. (2010). Counterconditioning reduces cue-induced craving and actual cue-elicited consumption. Emotion, 10, 688-695. doi:10.1037/ a0019463
32. Volkow, N. D., Wang, G. J., Telang, F., Fowler, J. S., Logan, J., Childress, A. R., Wong, C. (2006). Cocaine cues and dopamine in dorsal striatum: Mechanism of craving in cocaine addiction. The Journal of Neuroscience, 26, 6583-6588. doi:10.1523/JNEUROSCI.1544-06.2006
33. Volkow, N. D., Wang, G. J., Telang, F., Fowler, J. S., Logan, J., Childress, A.R.,...Wong, C. (2008). Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues. NeuroImage, 39, 1266-1273. doi:10.1016/j.neuroimage.2007.09.059
34. Vurbic, D., & Bouton, M. E. (2011). Secondary extinction in Pavlovian fear conditioning. Learning & Behavior, 39, 202-211. doi:10.3758/ s13420-011-0017-7
35. Weeks, J. R. (1962). Experimental morphine addiction: Method for automatic intravenous injections in unrestrained rats. Science, 138, 143-144. doi:10.1126/science.138.3537.143
36. Weiss, S. J. (1970). An effective and economical sound attenuation chamber. Journal of the Experimental Analysis of Behavior, 13, 37-39. doi:10.1901/jeab.1970.13-37
37. Weiss, S. J. (1978). Discriminated response and incentive processes in operant conditioning: A two-factor model of stimulus control. Journal of the Experimental Analysis of Behavior, 30, 361-381. doi:10.1901/jeab .1978.30-361
38. Weiss, S. J., & Schindler, C. W. (1989). Integrating control generated by positive and negative reinforcement on an operant baseline: Appetitiveaversive interactions. Animal Learning & Behavior, 17, 433-446, doi: 10.3758/BF03205223
39. Weiss, S. J., Thomas, D. A., & Weissman, R. D. (1996). Combining operant-baseline-derived conditioned excitors and inhibitors from the same and different incentive classes: An investigation of appetitiveaversive interactions. The Quarterly Journal of Experimental Psychology B: Comparative and Physiological Psychology, 49, 357-381.
40. Xue, Y. X., Luo, Y. X., Wu, P., Shi, H. S., Xue, L. F., Chen, C.,...Lu, L. (2012). A memory retrieval-extinction procedure to prevent drug craving and relapse. Science, 336, 241-245. doi:10.1126/science .1215070