Rate of renal graft function decline after one year is a strong predictor of all-cause mortality

American Journal of Transplantation

Volumn 13, Issue 3, 2013, Pages 695-706

  Moranne, O ^a   Maillard, N ^b   Fafin, C ^a   Thibaudin, L ^b   Alamartine, E ^b   Mariat, C ^b  

^a Hôpital Pasteur et Larchet   (France)

^b UNIVERSITÉ JEAN MONNET   (France)

Author keywords

Chronic kidney disease; disease progression; glomerular filtration rate; kidney transplantation; mortality

Indexed keywords

CALCINEURIN INHIBITOR; IMMUNOSUPPRESSIVE AGENT; INULIN;

ADULT; ARTICLE; CHRONIC KIDNEY DISEASE; COHORT ANALYSIS; DEMOGRAPHY; DISEASE COURSE; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HLA MATCHING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INULIN CLEARANCE; KIDNEY FUNCTION; KIDNEY GRAFT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTION; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY;

ADULT; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PROGNOSIS; RISK FACTORS; SURVIVAL RATE; TIME FACTORS;

EID: 84874438249     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12053     Document Type: Article

References (32)

1. Flechner SM, Kobashigawa J, Klintmalm G,. Calcineurin inhibitor-sparing regimens in solid organ transplantation: Focus on improving renal function and nephrotoxicity. Clin Transplant 2008; 22: 1-15.
2. White CA, Siegal D, Akbari A, Knoll GA,. Use of kidney function end points in kidney transplant trials: A systematic review. Am J Kidney Dis 2010; 56: 1140-1157.
3. Kasiske BL, Israni AK, Snyder JJ, Skeans MA,. The relationship between kidney function and long-term graft survival after kidney transplant. Am J Kidney Dis 2011; 57: 466-475.
4. Kaplan B, Schold J, Meier-Kriesche HU,. Poor predictive value of serum creatinine for renal allograft loss. Am J Transplant 2003; 3: 1560-1565.
5. He X, Moore J, Shabir S, et al. Comparison of the predictive performance of eGFR formulae for mortality and graft failure in renal transplant recipients. Transplantation 2009; 87: 384-392.
6. Kasiske BL, Zeier MG, Chapman JR, et al. KDIGO clinical practice guideline for the care of kidney transplant recipients: A summary. Kidney Int 2010; 77: 299-311.
7. Rifkin DE, Shlipak MG, Katz R, et al. Rapid kidney function decline and mortality risk in older adults. Arch Inter Med 2008; 168: 2212-2218.
8. Matsushita K, Selvin E, Bash LD, Franceschini N, Astor BC, Coresh J,. Change in estimated GFR associates with coronary heart disease and mortality. J Am Soc Nephrol 2009; 20: 2617-2624.
9. Cheng TY, Wen SF, Astor BC, Tao XG, Samet JM, Wen CP,. Mortality risks for all causes and cardiovascular diseases and reduced GFR in a middle-aged working population in Taiwan. Am J Kidney Dis 2008; 52: 1051-1060.
10. Perkins RM, Bucaloiu ID, Kirchner HL, Ashouian N, Hartle JE, Yahya T,. GFR decline and mortality risk among patients with chronic kidney disease. Clin J Am Soc Nephrol 2011; 6: 1879-1886.
11. Fellstrom B, Jardine AG, Soveri I, et al. Renal dysfunction is a strong and independent risk factor for mortality and cardiovascular complications in renal transplantation. Am J Transplant 2005; 5: 1986-1991.
12. Meier-Kriesche HU, Baliga R, Kaplan B,. Decreased renal function is a strong risk factor for cardiovascular death after renal transplantation. Transplantation 2003; 75: 1291-1295.
13. Soveri I, Holdaas H, Jardine A, Gimpelewicz C, Staffler B, Fellstrom B,. Renal transplant dysfunction-importance quantified in comparison with traditional risk factors for cardiovascular disease and mortality. Nephrol Dial Transplant 2006; 21: 2282-2289.
14. Excerpts from the United States Renal Data System. 2008 Annual Data Report: Atlas of chronic kidney disease & end-stage renal disease in the United States. Am J Kidney Dis 2009; 53: S1-S372.
15. Schnitzler MA, Johnston K, Axelrod D, Gheorghian A, Lentine KL,. Associations of renal function at 1-year after kidney transplantation with subsequent return to dialysis, mortality, and healthcare costs. Transplantation 2011; 91: 1347-1356.
16. Al-Aly Z, Zeringue A, Fu J, et al. Rate of kidney function decline associates with mortality. J Am Soc Nephrol 2010; 21: 1961-1969.
17. Gill JS, Tonelli M, Mix CH, Pereira BJ,. The change in allograft function among long-term kidney transplant recipients. J Am Soc Nephrol 2003; 14: 1636-1642.
18. Kasiske BL, Gaston RS, Gourishankar S, et al. Long-term deterioration of kidney allograft function. Am J Transplant 2005; 5: 1405-1414.
19. Mariat C, Alamartine E, Barthelemy JC, et al. Assessing renal graft function in clinical trials: Can tests predicting glomerular filtration rate substitute for a reference method? Kidney Int z 2004; 65: 289-297.
20. Pantazis N, Touloumi G,. Robustness of a parametric model for informatively censored bivariate longitudinal data under misspecification of its distributional assumptions: A simulation study. Statistics Med 2007; 26: 5473-5485.
21. Laird NM, Ware JH,. Random-effects models for longitudinal data. Biometrics 1982; 38: 963-974.
22. Thiebaut R, Walker S,. When it is better to estimate a slope with only one point. QJM 2008; 101: 821-824.
23. Perkins BA, Nelson RG, Ostrander BE, et al. Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: Results of a 4-year follow-up study. JJ Am Soc Nephrol 2005; 16: 1404-1412.
24. Rule AD, Torres VE, Chapman AB, et al. Comparison of methods for determining renal function decline in early autosomal dominant polycystic kidney disease: The consortium of radiologic imaging studies of polycystic kidney disease cohort. J Am Soc Nephrol 2006; 17: 854-862.
25. Bland JM, Altman DG,. Transforming data. Br Med J 1996; 312: 770.
26. Meier-Kriesche HU, Kaplan B,. Death after graft loss: A novel endpoint for renal transplantation. Transplant Proc 2001; 33: 3405-3406.
27. Fine JP GR,. A proportional hazards models for the subdistribution of a competing risk. J Am Stat Assoc 1999; 94: 496-509.
28. Rizopoulos D. JM,. An R package for the joint modelling of longitudinal and time-to-event data. Journal of Statistical Software 2010; 35 (9).
29. Marcen R, Morales JM, Fernandez-Rodriguez A, et al. Long-term graft function changes in kidney transplant recipients. NDT Plus 2010; 3: ii2-ii8.
30. Gourishankar S, Hunsicker LG, Jhangri GS, Cockfield SM, Halloran PF,. The stability of the glomerular filtration rate after renal transplantation is improving. J Am Soc Nephrol 2003; 14: 2387-2394.
31. Gera M, Slezak JM, Rule AD, Larson TS, Stegall MD, Cosio FG,. Assessment of changes in kidney allograft function using creatinine-based estimates of glomerular filtration rate. Am J Transplant 2007; 7: 880-887.
32. Levey AS, Gassman JJ, Hall PM, Walker WG,. Assessing the progression of renal disease in clinical studies: Effects of duration of follow-up and regression to the mean. Modification of Diet in Renal Disease (MDRD) Study Group. JJ Am Soc Nephrol 1991; 1: 1087-1094.