GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas

Nature

Volumn 494, Issue 7438, 2013, Pages 484-488

  Atwood, Scott X ^a   Li, Mischa ^a   Lee, Alex ^a   Tang, Jean Y ^a   Oro, Anthony E ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN KINASE C LAMBDA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

CANCER; CELL ORGANELLE; DRUG; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; GROWTH RATE; GROWTH REGULATOR; INHIBITOR; MEMBRANE; PROTEIN; SIGNALING; TUMOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL CELL CARCINOMA; CANCER GROWTH; CANCER RESISTANCE; CELL PROLIFERATION; DNA BINDING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CARCINOMA, BASAL CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; CENTROSOME; DRUG RESISTANCE, NEOPLASM; FEEDBACK, PHYSIOLOGICAL; HEDGEHOG PROTEINS; HUMANS; ISOENZYMES; KERATINOCYTES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84874359079     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11889     Document Type: Article

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