HIF-1α is a protective factor in conditional PHD2-βdeficient mice suffering from severe HIF-2-induced excessive erythropoiesis

Blood

Volumn 121, Issue 8, 2013, Pages 1436-1445

  Franke, Kristin ^a   Kalucka, Joanna ^a   Mamlouk, Soulafa ^a   Singh, Rashim Pal ^a   Muschter, Antje ^a   Weidemann, Alexander ^b   Iyengar, Vasuprada ^a   Jahn, Steffen ^a   Wieczorek, Kathrin ^a   Geiger, Kathrin ^a   Muders, Michael ^a   Sykes, Alex M ^c   Poitz, David M ^a   Ripich, Tatsiana ^a   Otto, Teresa ^d   Bergmann, Sybille ^a   Breier, Georg ^a,e   Baretton, Gustavo ^a   Fong, Guo Hua ^f   Greaves, David R ^g   Bornstein, Stefan ^h   Chavakis, Triantafyllos ^h   Joachim Fandrey, Max Gassmann ^d,i,j   Wielockx, Ben ^a,e   more..

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^f UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

ⁱ UNIVERSITY OF ZURICH   (Switzerland)

^j UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

more..

Author keywords

hif 1 protects conditional phd2 deficient mice; loss of phd2 induces hif 2 induced erythrocytosis

Indexed keywords

ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

ANEMIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; ENZYME INACTIVATION; ERYTHROCYTOSIS; ERYTHROPOIESIS; FEMALE; GENE INACTIVATION; GENE LOSS; GENE OVEREXPRESSION; HUMAN; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; THROMBOCYTOPENIA;

EID: 84874351409     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-08-449181     Document Type: Article

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