Physicians' preparedness for integration of genomic and pharmacogenetic testing into practice within a major healthcare system

Genetic Testing and Molecular Biomarkers

Volumn 17, Issue 3, 2013, Pages 219-225

  Selkirk, Christina G ^a   Weissman, Scott M ^a   Anderson, Andy ^a   Hulick, Peter J ^a,b  

^a NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL PRACTICE; EDUCATION; EXPECTATION; GENOME; HEALTH CARE POLICY; HEALTH CARE SYSTEM; HUMAN; KNOWLEDGE; PERCEPTION; PHARMACOGENETICS; PHYSICIAN;

CHICAGO; DELIVERY OF HEALTH CARE; GENETIC TESTING; GENOMICS; HUMANS; PHARMACOGENETICS; PHYSICIANS;

EID: 84874317701     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2012.0165     Document Type: Article

References (32)

1. ABMG (2011) Number of Certified Genetic Specialists. American Board of Medical Genetics. http://www.abmg.org/pdf/ SpecalistsByState.pdf accessed 8-2-2012.
2. Avard D, Knoppers BM (2009) Genomic medicine: considerations for health professionals and the public. Genome Med 1:25.
3. Baars MJ, Henneman L, ten Kate LP (2005) Deficiency of knowledge of genetics and genetic tests among general practitioners, gynecologists, and pediatricians: a global problem. Genet Med 7:605-610. (Pubitemid 41753011)
4. Bloss CS, Schork NJ, Topol EJ (2011) Effect of direct-to-consumer genomewide profiling to assess disease risk. N Engl J Med 364:524-534.
5. Carroll JC, Brown JB, Blaine S, et al. (2003) Genetic susceptibility to cancer. Family physicians' experience. Can Fam Physician 49:45-52. (Pubitemid 36149891)
6. Cooksey JA, Forte G, Benkendorf J, et al. (2005) The state of the medical geneticist workforce: findings of the 2003 survey of American Board of Medical Genetics certified geneticists. Genet Med 7:439-443. (Pubitemid 41139629)
7. Drmanac R (2011) The advent of personal genome sequencing. Genet Med 13:188-190.
8. Emery J, Hayflick S (2001) The challenge of integrating genetic medicine into primary care. BMJ 322:1027-1030. (Pubitemid 32391838)
9. Emery J, Watson E, Rose P, et al. (1999) A systematic review of the literature exploring the role of primary care in genetic services. Fam Pract 16:426-445. (Pubitemid 29410766)
10. FDA (2011) Pharmacogenomic Biomarkers in Drug Labels. U.S.Department of Health and Human Services, Food and Drug Administration. www.fda.gov/Drugs/ ScienceResearch/ ResearchAreas/Pharmacogenetics/ucm083378.htm accessed 9/29/2011
11. Feero WG (2008) Genetics of common disease: a primary care priority aligned with a teachable moment? GenetMed 10:81-82. (Pubitemid 351271718)
12. Finn CT, Wilcox MA, Korf BR, et al. (2005) Psychiatric genetics: a survey of psychiatrists' knowledge, opinions, and practice patterns. J Clin Psychiatry 66:821-830. (Pubitemid 41032822)
13. Frueh FW (2011) Considerations for safety pharmacogenetics in clinical practice. Drug Discov Today 16:898-901.
14. Frueh FW, Gurwitz D (2004) From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community. Pharmacogenomics 5:571-579. (Pubitemid 39023073)
15. Fry A, Campbell H, Gudmunsdottir H, et al. (1999) GPs' views on their role in cancer genetics services and current practice. Family Pract 16:468-474. (Pubitemid 29486134)
16. Ginsburg GS (2008) ''Grand challenges'' in the translation of genomics to human health. Eur J Hum Genet 16:873-874.
17. Guttmacher AE, Porteous ME, McInerney JD (2007) Educating health-care professionals about genetics and genomics. Nat Rev Genet 8:151-157. (Pubitemid 46122843)
18. Haga S, Burke W, Ginsburg G, et al. (2012) Primary care physicians' knowledge of and experience with pharmacogenetic testing. Clin Genet 82:388-394.
19. Hofman KJ, Tambor ES, Chase GA, et al. (1993) Physicians' knowledge of genetics and genetic tests. Acad Med 68:625-632. (Pubitemid 23241825)
20. Houwink EJ, van Luijk SJ, Henneman L, et al. (2011) Genetic educational needs and the role of genetics in primary care: a focus group study with multiple perspectives. BMC Fam Pract 12:5.
21. Hunter A, Wright P, Cappelli M, et al. (1998) Physician knowledge and attitudes towards molecular genetic (DNA) testing of their patients. Clin Genet 53:447-455. (Pubitemid 28327737)
22. Kolor K, Liu T, St PJ, et al. (2009) Health care provider and consumer awareness, perceptions, and use of direct-toconsumer personal genomic tests, United States, 2008. Genet Med 11:595.
23. Metcalfe S, Hurworth R, Newstead J, et al. (2002) Needs assessment study of genetics education for general practitioners in Australia. Genet Med 4:71-77. (Pubitemid 44698581)
24. Ormond KE, Hudgins L, Ladd JM, et al. (2011) Medical and graduate students' attitudes toward personal genomics. Genet Med 13:400-408.
25. Powell KP, Cogswell WA, Christianson CA, et al. (2012) Primary care physicians' awareness, experience and opinions of directto- consumer genetic testing. J Genet Couns 21:113-126.
26. Scheuner MT, Sieverding P, Shekelle PG (2008) Delivery of genomic medicine for common chronic adult diseases: a systematic review. JAMA 299:1320-1334. (Pubitemid 351439078)
27. Stanek EJ, Sanders CL, Teagarden JR, et al. (2009) Who are adopters of pharmacogenomics among U.S. physicians? Poster presented at Am Society of Hum Genet, 59th Annual Meeting, Honolulu.
28. Stanek EJ, Sanders CL, Taber KA, et al. (2012) Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey. Clin Pharmacol Ther 91:450-458.
29. Suther S, Goodson P (2003) Barriers to the provision of genetic services by primary care physicians: a systematic review of the literature. Genet Med 5:70-76. (Pubitemid 36992615)
30. Valle D, Manolio T (2008) Applying genomics to clinical problems- diagnostics, preventive medicine, pharmacogenomics. A white paper for the National Human Genome Research Institute. http://www.genome.gov/27529204 accessed 9-29- 2011.
31. Wilkins-Haug L, Erickson K, Hill L, et al. (2000a) Obstetriciangynecologists' opinions and attitudes on the role of genetics in women's health. JWomens Health Gend Based Med 9:873- 879.
32. Wilkins-Haug L, Hill LD, Power ML, et al. (2000b) Gynecologists' training, knowledge, and experiences in genetics: a survey. Obstet Gynecol 95:421-424.