A novel fully human antitumor ImmunoRNase resistant to the RNase inhibitor

Protein Engineering, Design and Selection

Volumn 26, Issue 3, 2013, Pages 243-248

  Riccio, Gennaro ^a   D'avino, Chiara ^a   Raines, Ronald T ^b   De Lorenzo, Claudia ^a,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

breast cancer; ErbB2; human RNase; immunotherapy; RNase inhibitor

Indexed keywords

BREAST CANCER; ERBB2; HUMAN RNASE; IMMUNOTHERAPY; RNASE INHIBITOR;

AMINO ACIDS; BENCHMARKING; TUMORS;

ANTIBODIES;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; PANCREATIC RIBONUCLEASE; RIBONUCLEASE INHIBITOR; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TRASTUZUMAB;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER IMMUNOTHERAPY; ENZYME ACTIVITY; ENZYME BINDING; HUMAN; HUMAN CELL; IMMUNOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FEMALE; HUMANS; IMMUNOTHERAPY; MICE; MIDDLE AGED; PROTEIN ENGINEERING; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE, PANCREATIC; SINGLE-CHAIN ANTIBODIES;

EID: 84874285226     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzs101     Document Type: Article

References (35)

1. Agus,D.B., Scher,H.I., Higgins,B., Fox,W.D., Heller,G., Fazzari,M., Cordon-Cardo,C. and Golde,D.W. (1999) Cancer Res., 59, 4761-4764
2. Bartholeyns,J., Wang,D., Blackburn,P., Wilson,G., Moore,S. and Stein,W.H. (1977) Int. J. Pept. Protein Res., 10, 172-175
3. Baselga,J. and Albanell,J. (2001) Ann. Oncol., 12(Suppl. 1), S35-41
4. Borriello,M., Laccetti,P., Terrazzano,G., D'Alessio,G. and De Lorenzo,C. (2011) Br. J. Cancer, 104, 1716-1723
5. Carter,P. (2001) Nat. Rev. Cancer, 1, 118-129
6. Castellano,I., Ruocco,M.R., Cecere,F., Di Maro,A., Chambery,A., Michniewicz,A., Parlato,G., Masullo,M. and De Vendittis,E. (2008 Biochim. Biophys. Acta, 1784, 816-826
7. De Lorenzo,C., Arciello,A., Cozzolino,R., Palmer,D.B., Laccetti,P., Piccoli,R. and D'Alessio,G. (2004) Cancer Res., 64, 4870-4874
8. De Lorenzo,C. and D'Alessio,G. (2008) Curr. Pharm. Biotechnol., 9, 210-214
9. De Lorenzo,C. and D'Alessio,G. (2009) FEBS J, 276, 1527-1535
10. De Lorenzo,C., Di Malta,C., Cali,G., Troise,F., Nitsch,L. and D'Alessio,G. (2007) FEBS Lett., 581, 296-300
11. De Lorenzo,C., Palmer,D.B., Piccoli,R., Ritter,M.A. and D'Alessio,G. (2002) Clin. Cancer Res., 8, 1710-1719
12. Dickson,K.A., Haigis,M.C. and Raines,R.T. (2005) Prog. Nucleic Acid Res. Mol. Biol., 80, 349-374
13. Fukushige,S., Matsubara,K., Yoshida,M., Sasaki,M., Suzuki,T., Semba,K., Toyoshima,K. and Yamamoto,T. (1986) Mol. Cell. Biol., 6, 955-958
14. Gelardi,T., Damiano,V., Rosa,R., Bianco,R., Cozzolino,R., Tortora,G., Laccetti,P., D'Alessio,G. and De Lorenzo,C. (2010) Br. J. Cancer, 102, 513-519
15. Gong,S.J., Jin,C.J., Rha,S.Y. and Chung,H.C. (2004) Cancer Lett., 214, 215-224
16. Haigis,M.C., Kurten,E.L. and Raines,R.T. (2003) Nucleic Acids Res., 31, 1024-1032
17. Johnson,R.J., Chao,T.Y., Lavis,L.D. and Raines,R.T. (2007a) Biochemistry, 46, 10308-10316
18. Johnson,R.J., McCoy,J.G., Bingman,C.A., Phillips,G.N., Jr and Raines,R.T. (2007b) J. Mol. Biol., 368, 434-449
19. Klapper,L.N., Kirschbaum,M.H., Sela,M. and Yarden,Y. (2000) Adv. Cancer Res., 77, 25-79
20. Kobe,B. and Deisenhofer,J. (1995) Nature, 374, 183-186
21. Nahta,R., Yu,D., Hung,M.C., Hortobagyi,G.N. and Esteva,F.J. (2006) Nat. Clin. Pract. Oncol., 3, 269-280
22. Pastan,I. and FitzGerald,D. (1991) Science, 254, 1173-1177
23. Press,M.F., Cordon-Cardo,C. and Slamon,D.J. (1990) Oncogene, 5, 953-962
24. Reiter,Y. and Pastan,I. (1998) Trends Biotechnol., 16, 513-520
25. Rybak,S.M. and Newton,D.L. (1999) Exp. Cell. Res., 253, 325-335
26. Schindler,J., Sausville,E., Messmann,R., Uhr,J.W. and Vitetta,E.S. (2001 Clin. Cancer Res., 7, 255-258
27. Seidman,A., Hudis,C., Pierri,M.K., Shak,S., Paton,V., Ashby,M., Murphy,M., Stewart,S.J. and Keefe,D. (2002) J. Clin. Oncol., 20, 1215-1221
28. Slamon,D.J., Clark,G.M., Wong,S.G., Levin,W.J., Ullrich,A. and McGuire,W.L. (1987) Science, 235, 177-182
29. Slamon,D.J., Godolphin,W., Jones,L.A., et al. (1989) Science, 244, 707-712
30. Slamon,D.J., Leyland-Jones,B., Shak,S., et al. (2001) N. Engl. J. Med., 344, 783-792
31. Stebbing,J., Copson,E. and O'Reilly,S. (2000) Cancer Treat. Rev., 26, 287-290
32. Tagliabue,E., Centis,F., Campiglio,M., et al. (1991) Int. J. Cancer, 47, 933-937
33. Troise,F., Monti,M., Merlino,A., Cozzolino,F., Fedele,C., Russo Krauss,I., Sica,F., Pucci,P., D'Alessio,G. and De Lorenzo,C. (2011) FEBS J., 278, 1156-1166
34. Weiner,L.M., O'Dwyer,J., Kitson,J., Comis,R.L., Frankel,A.E., Bauer,R.J., Konrad,M.S. and Groves,E.S. (1989) Cancer Res., 49, 4062-4067
35. Zhang,Q., Chen,G., Liu,X. and Qian,Q. (2007) Cell. Res., 17, 89-99