Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages

  Park, Chungoo ^a   Chen, Xiaoshu ^a   Yang, Jian Rong ^a   Zhang, Jianzhi ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Messenger RNA; Nonsynonymous substitution rate; Synonymous substitution rate

Indexed keywords

MESSENGER RNA; NUCLEOTIDE; PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CODON; GENE EXPRESSION; GENE MUTATION; MOLECULAR EVOLUTION; NATURAL SELECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA FOLDING; YEAST;

GENE EXPRESSION REGULATION, FUNGAL; MUTATION; NUCLEIC ACID CONFORMATION; PROTEINS; RNA, FUNGAL; RNA, MESSENGER;

EID: 84874250754     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1218066110     Document Type: Article

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