Local and long-range functional connectivity is reduced in concert in autism spectrum disorders

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages 3107-3112

  Khan, Sheraz ^a,b   Gramfort, Alexandre ^a,b   Shetty, Nandita R ^a,b   Kitzbichler, Manfred G ^a,b   Ganesan, Santosh ^a,b   Moran, Joseph M ^b,c   Lee, Su Mei ^b,c   Gabrieli, John D E ^b,c   Tager Flusberg, Helen B ^d   Joseph, Robert M ^e   Herbert, Martha R ^a,b   Hämäläinen, Matti S ^a,b   Kenet, Tal ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d BOSTON UNIVERSITY   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coherence; Parvalbumin

Indexed keywords

ADULT; ANTERIOR CINGULATE; ARTICLE; AUTISM; CLINICAL ARTICLE; CONNECTOME; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; EVOKED RESPONSE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUSIFORM FACE AREA; FUSIFORM GYRUS; HUMAN; INFERIOR FRONTAL GYRUS; MAGNETOENCEPHALOGRAPHY; MALE; OSCILLATION; PRECUNEUS; PRIORITY JOURNAL; VISUAL CORTEX;

ADOLESCENT; ADULT; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; ELECTROENCEPHALOGRAPHY; HUMANS; MAGNETOENCEPHALOGRAPHY; YOUNG ADULT;

EID: 84874248556     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214533110     Document Type: Article

References (62)

1. Uhlhaas P, et al. (2009) Neural synchrony in cortical networks: History, concept and current status. Frontiers in Integrative Neuroscience 3 (17):1-19.
2. Uhlhaas PJ, Singer W (2006) Neural synchrony in brain disorders: Relevance for cognitive dysfunctions and pathophysiology. Neuron 52 (1):155-168.
3. Uhlhaas PJ, Singer W (2007) What do disturbances in neural synchrony tell us about autism? Biol Psychiatry 62 (3):190-191.
4. Just MA, Cherkassky VL, Keller TA, Minshew NJ (2004) Cortical activation and synchronization during sentence comprehension in high-functioning autism: Evidence of underconnectivity. Brain 127 (Pt 8):1811-1821.
5. Belmonte MK, et al. (2004) Autism and abnormal development of brain connectivity. J Neurosci 24 (42):9228-9231.
6. Rubenstein JL, Merzenich MM (2003) Model of autism: Increased ratio of excitation/inhibition in key neural systems. Genes Brain Behav 2 (5):255-267.
7. Minshew NJ, Williams DL (2007) The new neurobiology of autism: Cortex, connectivity, and neuronal organization. Arch Neurol 64 (7):945-950.
8. Casanova MF, Buxhoeveden D, Gomez J (2003) Disruption in the inhibitory architecture of the cell minicolumn: Implications for autism. Neuroscientist 9 (6):496-507.
9. Fatemi SH, Reutiman TJ, Folsom TD, Thuras PD (2009) GABA (A) receptor down-regulation in brains of subjects with autism. J Autism Dev Disord 39 (2):223-230.
10. Ma DQ, et al. (2005) Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. Am J Hum Genet 77 (3):377-388.
11. Müller RA, et al. (2011) Underconnected, but how? A survey of functional connectivity MRI studies in autism spectrum disorders. Cereb Cortex 21 (10):2233-2243.
12. Murias M, Webb SJ, Greenson J, Dawson G (2007) Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Biol Psychiatry 62 (3):270-273.
13. Buzsáki G, Wang XJ (2012) Mechanisms of gamma oscillations. Annu Rev Neurosci 35:203-225.
14. Brown C, Gruber T, Boucher J, Rippon G, Brock J (2005) Gamma abnormalities during perception of illusory figures in autism. Cortex 41 (3):364-376.
15. Orekhova EV, et al. (2007) Excess of high frequency electroencephalogram oscillations in boys with autism. Biol Psychiatry 62 (9):1022-1029.
16. Braeutigam S, Swithenby SJ, Bailey AJ (2008) Contextual integration the unusual way: A magnetoencephalographic study of responses to semantic violation in individuals with autism spectrum disorders. Eur J Neurosci 27 (4):1026-1036.
17. Wilson TW, Rojas DC, Reite ML, Teale PD, Rogers SJ (2007) Children and adolescents with autism exhibit reduced MEG steady-state gamma responses. Biol Psychiatry 62 (3):192-197.
18. Rojas DC, Maharajh K, Teale P, Rogers SJ (2008) Reduced neural synchronization of gamma-band MEG oscillations in first-degree relatives of children with autism. BMC Psychiatry 8:66.
19. Gandal MJ, et al. (2010) Validating γ oscillations and delayed auditory responses as translational biomarkers of autism. Biol Psychiatry 68 (12):1100-1106.
20. Yuval-Greenberg S, Tomer O, Keren AS, Nelken I, Deouell LY (2008) Transient induced gamma-band response in EEG as a manifestation of miniature saccades. Neuron 58 (3):429-441.
21. Carl C, Açik A, König P, Engel AK, Hipp JF (2012) The saccadic spike artifact in MEG. Neuroimage 59 (2):1657-1667.
22. Kemner C, Verbaten MN, Cuperus JM, Camfferman G, van Engeland H (1998) Abnormal saccadic eye movements in autistic children. J Autism Dev Disord 28 (1):61-67.
23. Russo NM, et al. (2008) Deficient brainstem encoding of pitch in children with Autism Spectrum Disorders. Clin Neurophysiol 119 (8):1720-1731.
24. Wass S (2011) Distortions and disconnections: Disrupted brain connectivity in autism. Brain Cogn 75 (1):18-28.
25. Vissers ME, Cohen MX, Geurts HM (2012) Brain connectivity and high functioning autism: A promising path of research that needs refined models, methodological convergence, and stronger behavioral links. Neurosci Biobehav Rev 36 (1):604-625.
26. Canolty RT, Knight RT (2010) The functional role of cross-frequency coupling. Trends Cogn Sci 14 (11):506-515.
27. Canolty RT, et al. (2006) High gamma power is phase-locked to theta oscillations in human neocortex. Science 313 (5793):1626-1628.
28. Wulff P, et al. (2009) Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons. Proc Natl Acad Sci USA 106 (9):3561-3566.
29. Bartos M, Vida I, Jonas P (2007) Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci 8 (1):45-56.
30. Sohal VS, Zhang F, Yizhar O, Deisseroth K (2009) Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature 459 (7247):698-702.
31. Anderson WS, Kudela P, Weinberg S, Bergey GK, Franaszczuk PJ (2009) Phase-dependent stimulation effects on bursting activity in a neural network cortical simulation. Epilepsy Res 84 (1):42-55.
32. Lin FH, et al. (2004) Spectral spatiotemporal imaging of cortical oscillations and interactions in the human brain. Neuroimage 23 (2):582-595.
33. Gogolla N, et al. (2009) Common circuit defect of excitatory-inhibitory balance in mouse models of autism. J Neurodev Disorders 1 (2):172-181.
34. Fries P (2005) A mechanism for cognitive dynamics: Neuronal communication through neuronal coherence. Trends Cogn Sci 9 (10):474-480.
35. Sirota A, et al. (2008) Entrainment of neocortical neurons and gamma oscillations by the hippocampal theta rhythm. Neuron 60 (4):683-697.
36. Canolty RT, et al. (2010) Oscillatory phase coupling coordinates anatomically dispersed functional cell assemblies. Proc Natl Acad Sci USA 107 (40):17356-17361.
37. Dinstein I, et al. (2011) Disrupted neural synchronization in toddlers with autism. Neuron 70 (6):1218-1225.
38. Geschwind DH, Levitt P (2007) Autism spectrum disorders: Developmental disconnection syndromes. Curr Opin Neurobiol 17 (1):103-111.
39. de Lange FP, Jensen O, Bauer M, Toni I (2008) Interactions between posterior gamma and frontal alpha/beta oscillations during imagined actions. Front Hum Neurosci 2:7.
40. Griesmayr B, Gruber WR, Klimesch W, Sauseng P (2010) Human frontal midline theta and its synchronization to gamma during a verbal delayed match to sample task. Neurobiol Learn Mem 93 (2):208-215.
41. Weigelt S, Koldewyn K, Kanwisher N (2012) Face identity recognition in autism spectrum disorders: A review of behavioral studies. Neurosci Biobehav Rev 36 (3):1060-1084.
42. Kleinhans NM, et al. (2008) Abnormal functional connectivity in autism spectrum disorders during face processing. Brain 131 (Pt 4):1000-1012.
43. Bailey AJ, Braeutigam S, Jousmäki V, Swithenby SJ (2005) Abnormal activation of face processing systems at early and intermediate latency in individuals with autism spectrum disorder: A magnetoencephalographic study. Eur J Neurosci 21 (9):2575-2585.
44. Kanwisher N, McDermott J, Chun MM (1997) The fusiform face area: A module in human extrastriate cortex specialized for face perception. J Neurosci 17 (11):4302-4311.
45. Deffke I, et al. (2007) MEG/EEG sources of the 170-ms response to faces are co-localized in the fusiform gyrus. Neuroimage 35 (4):1495-1501.
46. Maris E, Schoffelen JM, Fries P (2007) Nonparametric statistical testing of coherence differences. J Neurosci Methods 163 (1):161-175.
47. Pantazatos SP, Talati A, Pavlidis P, Hirsch J (2012) Cortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing. Neuro-image 61 (4):1355-1363.
48. Osipova D, Hermes D, Jensen O (2008) Gamma power is phase-locked to posterior alpha activity. PLoS ONE 3 (12):e3990.
49. Voytek B, et al. (2010) Shifts in gamma phase-amplitude coupling frequency from theta to alpha over posterior cortex during visual tasks. Front Hum Neurosci 4:191.
50. Axmacher N, et al. (2010) Cross-frequency coupling supports multi-item working memory in the human hippocampus. Proc Natl Acad Sci USA 107 (7):3228-3233.
51. Deruelle C, Rondan C, Gepner B, Tardif C (2004) Spatial frequency and face processing in children with autism and Asperger syndrome. J Autism Dev Disord 34 (2):199-210.
52. Pedregosa F, Varoquaux G, Gramfort A, Michel V, Thirion B (2011) Scikit-learn: Machine learning in Python. J Mach Learn Res 12:2825-2830.
53. Tommerdahl M, Tannan V, Holden JK, Baranek GT (2008) Absence of stimulus-driven synchronization effects on sensory perception in autism: Evidence for local under-connectivity? Behav Brain Funct 4:19.
54. Shukla DK, Keehn B, Smylie DM, Müller RA (2011) Microstructural abnormalities of short-distance white matter tracts in autism spectrum disorder. Neuropsychologia 49 (5):1378-1382.
55. Taulu S, Simola J (2006) Spatiotemporal signal space separation method for rejecting nearby interference in MEG measurements. Phys Med Biol 51 (7):1759-1768.
56. Taulu S, Kajola M, Simola J (2004) Suppression of interference and artifacts by the Signal Space Separation Method. Brain Topogr 16 (4):269-275.
57. Destrieux C, Fischl B, Dale A, Halgren E (2010) Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature. Neuroimage 53 (1): 1-15.
58. Lin FH, et al. (2006) Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimates. Neuroimage 31 (1):160-171.
59. Delorme A, Makeig S (2004) EEGLAB: An open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J Neurosci Methods 134 (1):9-21.
60. Oostenveld R, Fries P, Maris E, Schoffelen JM (2011) FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data. Comput Intell Neurosci 2011:156869.
61. Maris E, Oostenveld R (2007) Nonparametric statistical testing of EEG-and MEG-data. J Neurosci Methods 164 (1):177-190.
62. Tadel F, Baillet S, Mosher JC, Pantazis D, Leahy RM (2011) Brainstorm: A user-friendly application for MEG/EEG analysis. Comput Intell Neurosci 2011:879716.