Obesity in Patients Undergoing Dialysis and Kidney Transplantation

Advances in Chronic Kidney Disease

Volumn 20, Issue 2, 2013, Pages 128-134

  Friedman, Allon N ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dialysis; Diet; Obesity; Transplantation; Weight

Indexed keywords

AMFEBUTAMONE; PHENTERMINE; RIMONABANT; SERTRALINE; SIBUTRAMINE; TETRAHYDROLIPSTATIN;

AGE DISTRIBUTION; ANXIETY DISORDER; BODY COMPOSITION; BODY MASS; CARDIOVASCULAR MORTALITY; COMORBIDITY; CREATININE URINE LEVEL; DELAYED GRAFT FUNCTION; DEPRESSION; ETHNICITY; FAT MASS; FATIGUE; FECES INCONTINENCE; GLOMERULUS FILTRATION RATE; HEMODIALYSIS PATIENT; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; INSOMNIA; INSULIN RESISTANCE; INTRAABDOMINAL FAT; KIDNEY TRANSPLANTATION; LIFESTYLE; LIPID STORAGE; LIVING DONOR; MUSCLE MASS; NAUSEA; OBESITY; OUTCOME ASSESSMENT; PERITONEAL DIALYSIS; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; SKINFOLD THICKNESS; SLEEP DISORDER; SOCIAL STATUS; SUICIDE; SURGICAL INFECTION; SYSTEMATIC REVIEW (TOPIC); TACHYCARDIA; WAIST CIRCUMFERENCE; WEIGHT GAIN; WEIGHT REDUCTION; WOUND DEHISCENCE; XEROSTOMIA;

BODY MASS INDEX; CARDIOVASCULAR DISEASES; HUMANS; KIDNEY TRANSPLANTATION; OBESITY; PREVALENCE; RENAL DIALYSIS; RENAL INSUFFICIENCY, CHRONIC; WEIGHT LOSS;

EID: 84874244552     PISSN: 15485595     EISSN: 15485609     Source Type: Journal    
DOI: 10.1053/j.ackd.2012.10.009     Document Type: Review

References (57)

1. Agarwal R., Bills J.E., Light R.P. Diagnosing obesity by body mass index in chronic kidney disease: an explanation for the "obesity paradox?" Hypertension 2010, 56:893-900.
2. Leinig C., Pecoits-Filho R., Nascimento M.M., Goncalves S., Riella M.C., Martins C. Association between body mass index and body fat in chronic kidney disease stages 3 to 5, hemodialysis, and peritoneal dialysis patients. J Ren Nutr 2008, 18:424-429.
3. Bergman R.N., Kim S.P., Catalano K.J., et al. Why visceral fat is bad: mechanisms of the metabolic syndrome. Obesity (Silver Spring) 2006, 14(suppl 1):16S-19S.
4. Kramer H., Shoham D., McClure L.A., et al. Association of waist circumference and body mass index with all-cause mortality in CKD: The REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study. Am J Kidney Dis 2011, 58:177-185.
5. Postorino M., Marino C., Tripepi G., Zoccali C. Abdominal obesity and all-cause and cardiovascular mortality in end-stage renal disease. J Am Coll Cardiol 2009, 53:1265-1272.
6. World Health Organization Fact Sheet on obesity. Available at: Accessed October 5, 2012. http://www.who.int/dietphysicalactivity/media/en/gsfs_obesity.pdf.
7. Kramer H.J., Saranathan A., Luke A., et al. Increasing body mass index and obesity in the incident ESRD population. J Am Soc Nephrol 2006, 17:1453-1459.
8. Abbott K.C., Glanton C.W., Trespalacios F.C., et al. Body mass index, dialysis modality, and survival: analysis of the United States Renal Data System Dialysis Morbidity and Mortality Wave II Study. Kidney Int 2004, 65:597-605.
9. Friedman A.N., Miskulin D.C., Rosenberg I.H., Levey A.S. Demographics and trends in overweight and obesity in patients at time of kidney transplantation. Am J Kidney Dis 2003, 41:480-487.
10. Potluri K., Hou S. Obesity in kidney transplant recipients and candidates. Am J Kidney Dis 2010, 56:143-156.
11. Lentine K.L., Axelrod D., Abbott K.C. Interpreting body composition in kidney transplantation: weighing candidate selection, prognostication, and interventional strategies to optimize health. Clin J Am Soc Nephrol 2011, 6:1238-1240.
12. US Renal Data System, USRDS 2011 annual data report: atlas of end-stage renal disease in the United States 2011, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
13. Jolly S., Chatatalsingh C., Bargman J., Vas S., Chu M., Oreopoulos D.G. Excessive weight gain during peritoneal dialysis. Int J Artif Organs 2001, 24:197-202.
14. Rogers C.C., Alloway R.R., Buell J.F., et al. Body weight alterations under early corticosteroid withdrawal and chronic corticosteroid therapy with modern immunosuppression. Transplantation 2005, 80:26-33.
15. Levin N.W., Handelman G.J., Coresh J., Port F.K., Kaysen G.A. Reverse epidemiology: a confusing, confounding, and inaccurate term. Semin Dial 2007, 20:586-592.
16. Friedman A.N. Adiposity in dialysis: good or bad?. Semin Dial 2006, 19:136-140.
17. Calle E.E., Thun M.J., Petrelli J.M., Rodriguez C., Heath C.W. Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med 1999, 341:1097-1105.
18. Degoulet P., Legrain M., Reach I., et al. Mortality risk factors in patients treated by chronic hemodialysis. Report of the Diaphane collaborative study. Nephron 1982, 31:103-110.
19. Herselman M., Esau N., Kruger J.M., Labadarios D., Moosa M.R. Relationship between body mass index and mortality in adults on maintenance hemodialysis: a systematic review. J Ren Nutr 2010, 20:281-292. 7 p following 92.
20. Snyder J.J., Foley R.N., Gilbertson D.T., Vonesh E.F., Collins A.J. Body size and outcomes on peritoneal dialysis in the United States. Kidney Int 2003, 64:1838-1844.
21. Stack A.G., Murthy B.V., Molony D.A. Survival differences between peritoneal dialysis and hemodialysis among "large" ESRD patients in the United States. Kidney Int 2004, 65:2398-2408.
22. Ricks J., Molnar M.Z., Kovesdy C.P., et al. Racial and ethnic differences in the association of body mass index and survival in maintenance hemodialysis patients. Am J Kidney Dis 2011, 58:574-582.
23. Hoogeveen E.K., Halbesma N., Rothman K.J., et al. Obesity and mortality risk among younger dialysis patients. Clin J Am Soc Nephrol 2012, 7:280-288.
24. McDonald S.P., Collins J.F., Johnson D.W. Obesity is associated with worse peritoneal dialysis outcomes in the Australia and New Zealand patient populations. J Am Soc Nephrol 2003, 14:2894-2901.
25. Johansen K.L., Young B., Kaysen G.A., Chertow G.M. Association of body size with outcomes among patients beginning dialysis. Am J Clin Nutr 2004, 80:324-332.
26. Beddhu S., Pappas L.M., Ramkumar N., Samore M. Effects of body size and body composition on survival in hemodialysis patients. J Am Soc Nephrol 2003, 14:2366-2372.
27. Kalantar-Zadeh K., Streja E., Kovesdy C.P., et al. The obesity paradox and mortality associated with surrogates of body size and muscle mass in patients receiving hemodialysis. Mayo Clin Proc 2010, 85:991-1001.
28. Huang C.X., Tighiouart H., Beddhu S., et al. Both low muscle mass and low fat are associated with higher all-cause mortality in hemodialysis patients. Kidney Int 2010, 77:624-629.
29. Kakiya R., Shoji T., Tsujimoto Y., et al. Body fat mass and lean mass as predictors of survival in hemodialysis patients. Kidney Int 2006, 70:549-556.
30. Campbell K.L., MacLaughlin H.L. Unintentional weight loss is an independent predictor of mortality in a hemodialysis population. J Ren Nutr 2010, 20:414-418.
31. Kalantar-Zadeh K., Ikizler T.A., Block G., Avram M.M., Kopple J.D. Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences. Am J Kidney Dis 2003, 42:864-881.
32. Gregg E.W., Cheng Y.J., Cadwell B.L., et al. Secular trends in cardiovascular disease risk factors according to body mass index in US adults. JAMA 2005, 293:1868-1874.
33. Zoccali C., Postorino M., Marino C., Pizzini P., Cutrupi S., Tripepi G. Waist circumference modifies the relationship between the adipose tissue cytokines leptin and adiponectin and all-cause and cardiovascular mortality in haemodialysis patients. J Intern Med 2011, 269:172-181.
34. Chan M.R., Young H.N., Becker Y.T., Yevzlin A.S. Obesity as a predictor of vascular access outcomes: analysis of the USRDS DMMS Wave II study. Semin Dial 2008, 21:274-279.
35. Plumb T.J., Adelson A.B., Groggel G.C., Johanning J.M., Lynch T.G., Lund B. Obesity and hemodialysis vascular access failure. Am J Kidney Dis 2007, 50:450-454.
36. Aslam N., Bernardini J., Fried L., Piraino B. Large body mass index does not predict short-term survival in peritoneal dialysis patients. Perit Dial Int 2002, 22:191-196.
37. Johnson D.W., Isbel N.M., Brown A.M., et al. The effect of obesity on renal transplant outcomes. Transplantation 2002, 74:675-681.
38. Segev D.L., Simpkins C.E., Thompson R.E., Locke J.E., Warren D.S., Montgomery R.A. Obesity impacts access to kidney transplantation. J Am Soc Nephrol 2008, 19:349-355.
39. Glanton C.W., Kao T.C., Cruess D., Agodoa L.Y., Abbott K.C. Impact of renal transplantation on survival in end-stage renal disease patients with elevated body mass index. Kidney Int 2003, 63:647-653.
40. Meier-Kriesche H.U., Arndorfer J.A., Kaplan B. The impact of body mass index on renal transplant outcomes: a significant independent risk factor for graft failure and patient death. Transplantation 2002, 73:70-74.
41. Molnar M.Z., Kovesdy C.P., Mucsi I., et al. Higher recipient body mass index is associated with post-transplant delayed kidney graft function. Kidney Int 2011, 80:218-224.
42. Hoogeveen E.K., Aalten J., Rothman K.J., et al. Effect of obesity on the outcome of kidney transplantation: a 20-year follow-up. Transplantation 2011, 91:869-874.
43. Lentine K.L., Rocca-Rey L.A., Bacchi G., et al. Obesity and cardiac risk after kidney transplantation: experience at one center and comprehensive literature review. Transplantation 2008, 86:303-312.
44. Kovesdy C.P., Czira M.E., Rudas A., et al. Body mass index, waist circumference and mortality in kidney transplant recipients. Am J Transplant 2010, 10:2644-2651.
45. Streja E., Molnar M.Z., Kovesdy C.P., et al. Associations of pretransplant weight and muscle mass with mortality in renal transplant recipients. Clin J Am Soc Nephrol 2011, 6:1463-1473.
46. Molnar M.Z., Streja E., Kovesdy C.P., et al. Associations of body mass index and weight loss with mortality in transplant-waitlisted maintenance hemodialysis patients. Am J Transpl 2011, 11:725-736.
47. Schold J.D., Srinivas T.R., Guerra G., et al. A "weight-listing" paradox for candidates of renal transplantation?. Am J Transpl 2007, 7:550-559.
48. Kalantar-Zadeh K., Kopple J.D., Kilpatrick R.D., et al. Association of morbid obesity and weight change over time with cardiovascular survival in hemodialysis population. Am J Kidney Dis 2005, 46:489-500.
49. Navaneethan S., Kirwan J., Arrigain S., Schreiber M., Sehgal A., Schold S. Overweight, obesity and intentional weight loss in chronic kidney disease: NHANES 1999-2006. Int J Obes (Lond) 2012 Jan 31, [Epub ahead of print].
50. Modanlou K.A., Muthyala U., Xiao H., et al. Bariatric surgery among kidney transplant candidates and recipients: analysis of the United States renal data system and literature review. Transplantation 2009, 87:1167-1173.
51. Koshy A.N., Coombes J.S., Wilkinson S., Fassett R.G. Laparoscopic gastric banding surgery performed in obese dialysis patients prior to kidney transplantation. Am J Kidney Dis 2008, 52:e15-e17.
52. Jezior D., Krajewska M., Madziarska K., et al. Weight reduction in renal transplant recipients program: the first successes. Transplant Proc 2007, 39:2769-2771.
53. Patel M.G. The effect of dietary intervention on weight gains after renal transplantation. J Ren Nutr 1998, 8:137-141.
54. Rogers C.C., Alloway R.R., Alexander J.W., Cardi M., Trofe J., Vinks A.A. Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study. Clin Transplant 2008, 22:281-291.
55. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults 1998, National Institutes of Health: National Heart, Lung, and Blood Institute, Bethesda, MD.
56. Weir M.A., Beyea M.M., Gomes T., et al. Orlistat and acute kidney injury: an analysis of 953 patients. Arch Intern Med 2011, 171:703-704.
57. Kramer H., Tuttle K.R., Leehey D., et al. Obesity management in adults with CKD. Am J Kidney Dis 2009, 53:151-165.