Fascin-1 is a novel biomarker of aggressiveness in some carcinomas

BMC Medicine

Volumn 11, Issue 1, 2013, Pages

  Kulasingam, Vathany ^a,b   Diamandis, Eleftherios P ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

diagnosis; fascin 1; immunohistochemistry; prognosis; tumor markers

Indexed keywords

FASCIN; FASCIN 1; TUMOR MARKER; UNCLASSIFIED DRUG;

BILE DUCT CARCINOMA; BLADDER CANCER; BRAIN CANCER; BREAST CANCER; BREAST CARCINOMA; CANCER GROWTH; CANCER MORTALITY; CARCINOMA; COLORECTAL CANCER; DISTANT METASTASIS; ESOPHAGUS CANCER; HUMAN; KIDNEY CANCER; LIVER CANCER; LUNG CARCINOMA; LYMPH NODE METASTASIS; META ANALYSIS (TOPIC); NOTE; OVARY CANCER; PANCREAS CANCER; PROTEIN EXPRESSION; SYSTEMATIC REVIEW (TOPIC); TUMOR INVASION;

BIOLOGICAL MARKERS; CARCINOMA; CARRIER PROTEINS; FEMALE; HUMANS; MALE; MICROFILAMENT PROTEINS; NEOPLASM METASTASIS;

EID: 84874214606     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-11-53     Document Type: Note

References (8)

1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10. 2010, Lyon, France: International Agency for Research on Cancer., http://globocan.iarc.fr
2. Siegel R, Naishadham D, Jemal A. Cancer Statistics, 2013. CA Cancer J Clin 2013, 63:11-30. 10.3322/caac.21166, 23335087.
3. Etzioni R, Urban N, Ramsey S, McIntosh M, Schwartz S, Reid B, Radich J, Anderson G, Hartwell L. The case for early detection. Nat Rev Cancer 2003, 3:243-252.
4. Tan VY, Lewis SJ, Adams JC, Martin RM. Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis. BMC Medicine 2013, 11:52. 10.1186/1741-7015-11-52, 23442983.
5. Hashimoto Y, Kim DJ, Adams JC. The role of fascins in health and disease. J Pathol 2011, 224:289-300. 10.1002/path.2894, 21618240.
6. Hashimoto Y, Skacel M, Adams J. Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?. Int J Biochem Cell Biol 2005, 37:1787-804. 10.1016/j.biocel.2005.05.004, 16002322.
7. Hashimoto Y, Skacel M, Lavery IC, Mukherjee AL, Casey G, Adams JC. Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas. BMC Cancer 2006, 6:241. 10.1186/1471-2407-6-241, 1615879, 17029629.
8. Diamandis EP. The failure of protein cancer biomarkers to reach the clinic: Why and what can be done to address the problem?. BMC Med 2012, 10:87. 10.1186/1741-7015-10-87, 3425158, 22876833.