Characterization of NCI-H295R cells as an in vitro model of hyperaldosteronism

Hormone and Metabolic Research

Volumn 45, Issue 2, 2013, Pages 124-129

  Lichtenauer, U D ^a   Shapiro, I ^a   Osswald, A ^a   Meurer, S ^a   Kulle, A ^b   Reincke, M ^a   Riepe, F ^b   Beuschlein, F ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

adrenal tumor; aldosterone producing cell line; Conn's syndrome

Indexed keywords

ANGIOTENSIN II; CORTICOTROPIN; CYTOCHROME P450 17; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; POTASSIUM; STEROID;

ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CULTURE MEDIUM; HUMAN; HUMAN CELL; HYDROCORTISONE RELEASE; HYPERALDOSTERONISM; IN VITRO STUDY; PRIORITY JOURNAL; SPHEROID CELL; STEM CELL;

ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL CARCINOMA; ALDOSTERONE; ALDOSTERONE SYNTHASE; CELL ADHESION; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROCORTISONE; HYPERALDOSTERONISM; NEOPLASM PROTEINS; OSMOLAR CONCENTRATION; POTASSIUM; RNA, MESSENGER; SPHEROIDS, CELLULAR;

EID: 84874113440     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0032-1323810     Document Type: Article

References (20)

1. Schirpenbach C., Reincke M. Primary aldosteronism: current knowledge and controversies in Conn's syndrome. Nat Clin Pract Endocrinol Metab: 2007; 3 220 227
2. Reincke M., Beuschlein F., Bidlingmaier M., Funder J. W., Bornstein S. R. Progress in primary aldosteronism. Horm Metab Res: 2010; 42 371 373
3. Rainey W. E., Saner K., Schimmer B. P. Adrenocortical cell lines. Mol Cell Endocrinol: 2004; 228 23 38
4. Bird I. M., Hanley N. A., Word R. A., Mathis J. M., McCarthy J. L., Mason J. I., Rainey W. E. Human NCI-H295 adrenocortical carcinoma cells: a model for angiotensin-II-responsive aldosterone secretion. Endocrinology: 1993; 133 1555 1561
5. Gazdar A. F., Oie H. K., Shackleton C. H., Chen T. R., Triche T. J., Myers C. E., Chrousos G. P., Brennan M. F., Stein C. A., La Rocca R. V. Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis. Cancer Res: 1990; 50 5488 5496
6. Singh S. K., Clarke I. D., Terasaki M., Bonn V. E., Hawkins C., Squire J., Dirks P. B. Identification of a cancer stem cell in human brain tumors. Cancer Res: 2003; 63 5821 5828
7. Al-Hajj M., Wicha M. S., Benito-Hernandez A., Morrison S. J., Clarke M. F. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA: 2003; 100 3983 3988
8. Hirschmann-Jax C., Foster A. E., Wulf G. G., Nuchtern J. G., Jax T. W., Gobel U., Goodell M. A., Brenner M. K. A distinct "side populationo" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci USA: 2004; 101 14228 14233
9. Lichtenauer U. D., Shapiro I., Geiger K., Quinkler M., Fassnacht M., Nitschke R., Ruckauer K. D., Beuschlein F. Side population does not define stem cell-like cancer cells in the adrenocortical carcinoma cell line NCI h295R. Endocrinology: 2008; 149 1314 1322
10. Carpenter M. K., Cui X., Hu Z. Y., Jackson J., Sherman S., Seiger A., Wahlberg L. U. In vitro expansion of a multipotent population of human neural progenitor cells. Exp Neurol: 1999; 158 265 278
11. Chung K. F., Sicard F., Vukicevic V., Hermann A., Storch A., Huttner W. B., Bornstein S. R., Ehrhart-Bornstein M. Isolation of neural crest derived chromaffin progenitors from adult adrenal medulla. Stem Cells: 2009; 27 2602 2613
12. Dontu G., Al-Hajj M., Abdallah W. M., Clarke M. F., Wicha M. S. Stem cells in normal breast development and breast cancer. Cell Prolif: 2003; 36 01 59 72
13. Uchida N., Buck D. W., He D., Reitsma M. J., Masek M., Phan T. V., Tsukamoto A. S., Gage F. H., Weissman I. L. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci USA: 2000; 97 14720 14725
14. Zwermann O., Schulte D. M., Reincke M., Beuschlein F. ACTH 1-24 inhibits proliferation of adrenocortical tumors in vivo. Eur J Endocrinol: 2005; 153 435 444
15. Kulle A. E., Riepe F. G., Melchior D., Hiort O., Holterhus P. M. A novel ultrapressure liquid chromatography tandem mass spectrometry method for the simultaneous determination of androstenedione, testosterone, and dihydrotestosterone in pediatric blood samples: age- and sex-specific reference data. J Clin Endocrinol Metab: 2010; 95 2399 2409
16. Manolopoulou J., Mulatero P., Maser-Gluth C., Rossignol P., Spyroglou A., Vakrilova Y., Petersenn S., Zwermann O., Plouin P. F., Reincke M., Bidlingmaier M. Saliva as a medium for aldosterone measurement in repeated sampling studies. Steroids: 2009; 74 853 858
17. Wang T., Rowland J. G., Parmar J., Nesterova M., Seki T., Rainey W. E. Comparison of aldosterone production among human adrenocortical cell lines. Horm Metab Res: 2012; 44 245 250
18. Matthews E. K., Saffran M. Ionic dependence of adrenal steroidogenesis and ACTH-induced changes in the membrane potential of adrenocortical cells. J Physiol: 1973; 234 43 64
19. Saruta T., Kondo K., Saito I., Misumi J., Nakamura R., Kidokoro S., Matsuki S. Effects of low salt plus upright posture, angiotensin II, ACTH, and potassium upon plasma renin activity, aldosterone, and cortisol (author's transl). Nihon Naibunpi Gakkai Zasshi: 1975; 51 740 744
20. Boyd J. E., Palmore W. P., Mulrow P. J. Role of potassium in the control of aldosterone secretion in the rat. Endocrinology: 1971; 88 556 565