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Volumn 58, Issue 3, 2013, Pages 535-542

MicroRNA-29a-c decrease fasting blood glucose levels by negatively regulating hepatic gluconeogenesis

Author keywords

Diabetes; Gluconeogenesis; Glucose tolerance; miR 29a c; PGC 1

Indexed keywords

GLUCOSE; GLUCOSE 6 PHOSPHATASE; MICRORNA 29; MICRORNA 29A; MICRORNA 29B; MICRORNA 29C; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; UNCLASSIFIED DRUG;

EID: 84874113046     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.10.024     Document Type: Article
Times cited : (95)

References (32)
  • 1
    • 25144482864 scopus 로고    scopus 로고
    • Foxa2 integrates the transcriptional response of the hepatocyte to fasting
    • L. Zhang, N.E. Rubins, R.S. Ahima, L.E. Greenbaum, and K.H. Kaestner Foxa2 integrates the transcriptional response of the hepatocyte to fasting Cell Metab 2 2005 141 148
    • (2005) Cell Metab , vol.2 , pp. 141-148
    • Zhang, L.1    Rubins, N.E.2    Ahima, R.S.3    Greenbaum, L.E.4    Kaestner, K.H.5
  • 2
    • 0035936763 scopus 로고    scopus 로고
    • New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
    • A.R. Saltiel New perspectives into the molecular pathogenesis and treatment of type 2 diabetes Cell Metab 104 2001 517 529
    • (2001) Cell Metab , vol.104 , pp. 517-529
    • Saltiel, A.R.1
  • 3
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
    • S.J. Pilkis, and D.K. Granner Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis Annu Rev Physiol 54 1992 885 909
    • (1992) Annu Rev Physiol , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 4
    • 0035855905 scopus 로고    scopus 로고
    • CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
    • S. Herzig, F. Long, U.S. Jhala, S. Hedrick, R. Quinn, and A. Bauer CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nat Methods 413 2001 179 183
    • (2001) Nat Methods , vol.413 , pp. 179-183
    • Herzig, S.1    Long, F.2    Jhala, U.S.3    Hedrick, S.4    Quinn, R.5    Bauer, A.6
  • 5
    • 0035855858 scopus 로고    scopus 로고
    • Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    • J.C. Yoon, P. Puigserver, G. Chen, J. Donovan, Z. Wu, and J. Rhee Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 Nat Methods 413 2001 131 138
    • (2001) Nat Methods , vol.413 , pp. 131-138
    • Yoon, J.C.1    Puigserver, P.2    Chen, G.3    Donovan, J.4    Wu, Z.5    Rhee, J.6
  • 6
    • 0038187621 scopus 로고    scopus 로고
    • Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
    • P. Puigserver, J. Rhee, J. Donovan, C.J. Walkey, J.C. Yoon, and F. Oriente Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction Nat Methods 423 2003 550 555
    • (2003) Nat Methods , vol.423 , pp. 550-555
    • Puigserver, P.1    Rhee, J.2    Donovan, J.3    Walkey, C.J.4    Yoon, J.C.5    Oriente, F.6
  • 7
    • 0033522897 scopus 로고    scopus 로고
    • Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway
    • J. Nakae, B.C. Park, and D. Accili Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway J Biol Chem 274 1999 15982 15985
    • (1999) J Biol Chem , vol.274 , pp. 15982-15985
    • Nakae, J.1    Park, B.C.2    Accili, D.3
  • 8
    • 34548349302 scopus 로고    scopus 로고
    • Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor FOXO1 in liver
    • M. Matsumoto, A. Pocai, L. Rossetti, R.A. Depinho, and D. Accili Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor FOXO1 in liver Cell Metab 6 2007 208 216
    • (2007) Cell Metab , vol.6 , pp. 208-216
    • Matsumoto, M.1    Pocai, A.2    Rossetti, L.3    Depinho, R.A.4    Accili, D.5
  • 9
    • 33845596500 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
    • C. Handschin, and B.M. Spiegelman Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism Endocr Rev 27 2006 728 735
    • (2006) Endocr Rev , vol.27 , pp. 728-735
    • Handschin, C.1    Spiegelman, B.M.2
  • 10
    • 18244399631 scopus 로고    scopus 로고
    • Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1
    • P. Puigserver, J. Rhee, J. Lin, Z. Wu, J.C. Yoon, and C.Y. Zhang Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1 Mol Cell 8 2001 971 982
    • (2001) Mol Cell , vol.8 , pp. 971-982
    • Puigserver, P.1    Rhee, J.2    Lin, J.3    Wu, Z.4    Yoon, J.C.5    Zhang, C.Y.6
  • 11
    • 34250740323 scopus 로고    scopus 로고
    • Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator
    • X. Li, B. Monks, Q. Ge, and M.J. Birnbaum Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator Nat Methods 447 2007 1012 1016
    • (2007) Nat Methods , vol.447 , pp. 1012-1016
    • Li, X.1    Monks, B.2    Ge, Q.3    Birnbaum, M.J.4
  • 12
    • 72649098153 scopus 로고    scopus 로고
    • Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis
    • J.T. Rodgers, W. Haas, S.P. Gygi, and P. Puigserver Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis Cell Metab 11 2010 23 34
    • (2010) Cell Metab , vol.11 , pp. 23-34
    • Rodgers, J.T.1    Haas, W.2    Gygi, S.P.3    Puigserver, P.4
  • 13
    • 33744534726 scopus 로고    scopus 로고
    • GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha
    • C. Lerin, J.T. Rodgers, D.E. Kalume, S.H. Kim, A. Pandey, and P. Puigserver GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha Cell Metab 3 2006 429 438
    • (2006) Cell Metab , vol.3 , pp. 429-438
    • Lerin, C.1    Rodgers, J.T.2    Kalume, D.E.3    Kim, S.H.4    Pandey, A.5    Puigserver, P.6
  • 15
    • 2442701392 scopus 로고    scopus 로고
    • PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
    • S.H. Koo, H. Satoh, S. Herzig, C.H. Lee, S. Hedrick, and R. Kulkarni PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3 Nat Med 10 2004 530 534
    • (2004) Nat Med , vol.10 , pp. 530-534
    • Koo, S.H.1    Satoh, H.2    Herzig, S.3    Lee, C.H.4    Hedrick, S.5    Kulkarni, R.6
  • 16
    • 5344252327 scopus 로고    scopus 로고
    • Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
    • J. Lin, P.H. Wu, P.T. Tarr, K.S. Lindenberg, J. St-Pierre, and C.Y. Zhang Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice Cell Metab 119 2004 121 135
    • (2004) Cell Metab , vol.119 , pp. 121-135
    • Lin, J.1    Wu, P.H.2    Tarr, P.T.3    Lindenberg, K.S.4    St-Pierre, J.5    Zhang, C.Y.6
  • 17
    • 21144446106 scopus 로고    scopus 로고
    • PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
    • T.C. Leone, J.J. Lehman, B.N. Finck, P.J. Schaeffer, A.R. Wende, and S. Boudina PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis PLoS Biol 3 2005 e101
    • (2005) PLoS Biol , vol.3 , pp. 101
    • Leone, T.C.1    Lehman, J.J.2    Finck, B.N.3    Schaeffer, P.J.4    Wende, A.R.5    Boudina, S.6
  • 18
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • V. Ambros The functions of animal microRNAs Nat Methods 431 2004 350 355
    • (2004) Nat Methods , vol.431 , pp. 350-355
    • Ambros, V.1
  • 20
    • 80052099673 scopus 로고    scopus 로고
    • MicroRNAs in beta-cell biology, insulin resistance, diabetes and its complications
    • S.L. Fernandez-Valverde, R.J. Taft, and J.S. Mattick MicroRNAs in beta-cell biology, insulin resistance, diabetes and its complications Diabetes 60 2011 1825 1831
    • (2011) Diabetes , vol.60 , pp. 1825-1831
    • Fernandez-Valverde, S.L.1    Taft, R.J.2    Mattick, J.S.3
  • 21
    • 80052102044 scopus 로고    scopus 로고
    • Diabetes complications: The microRNA perspective
    • P. Kantharidis, B. Wang, R.M. Carew, and H.Y. Lan Diabetes complications: the microRNA perspective Diabetes 60 2011 1832 1837
    • (2011) Diabetes , vol.60 , pp. 1832-1837
    • Kantharidis, P.1    Wang, B.2    Carew, R.M.3    Lan, H.Y.4
  • 22
    • 35649011441 scopus 로고    scopus 로고
    • Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes
    • A. He, L. Zhu, N. Gupta, Y. Chang, and F. Fang Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes Mol Endocrinol 21 2007 2785 2794
    • (2007) Mol Endocrinol , vol.21 , pp. 2785-2794
    • He, A.1    Zhu, L.2    Gupta, N.3    Chang, Y.4    Fang, F.5
  • 23
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • M.S. Ebert, J.R. Neilson, and P.A. Sharp MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells Nat Methods 4 2007 721 726
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 24
    • 79960729651 scopus 로고    scopus 로고
    • Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis
    • A. Qiao, J. Liang, Y. Ke, C. Li, Y. Cui, and L. Shen Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis Hepatology 54 2011 509 521
    • (2011) Hepatology , vol.54 , pp. 509-521
    • Qiao, A.1    Liang, J.2    Ke, Y.3    Li, C.4    Cui, Y.5    Shen, L.6
  • 25
    • 0037262963 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells
    • J.N. Boustead, B.T. Stadelmaier, A.M. Eeds, P.O. Wiebe, C.A. Svitek, and J.K. Oeser Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells Biochem J 369 2003 17 22
    • (2003) Biochem J , vol.369 , pp. 17-22
    • Boustead, J.N.1    Stadelmaier, B.T.2    Eeds, A.M.3    Wiebe, P.O.4    Svitek, C.A.5    Oeser, J.K.6
  • 26
    • 28444483953 scopus 로고    scopus 로고
    • Insulin regulation of PEPCK gene expression: A model for rapid and reversible modulation
    • P.G. Quinn, and D. Yeagley Insulin regulation of PEPCK gene expression: a model for rapid and reversible modulation Curr Drug Targets Immune Endocr Metabol Disord 5 2005 423 437
    • (2005) Curr Drug Targets Immune Endocr Metabol Disord , vol.5 , pp. 423-437
    • Quinn, P.G.1    Yeagley, D.2
  • 27
    • 79951672283 scopus 로고    scopus 로고
    • Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas
    • E. Mutel, A. Abdul-Wahed, N. Ramamonjisoa, A. Stefanutti, and I. Houberdon Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas J Hepatol 54 2011 529 537
    • (2011) J Hepatol , vol.54 , pp. 529-537
    • Mutel, E.1    Abdul-Wahed, A.2    Ramamonjisoa, N.3    Stefanutti, A.4    Houberdon, I.5
  • 28
    • 39849095077 scopus 로고    scopus 로고
    • E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer
    • F. Petrocca, R. Visone, M.R. Onelli, M.H. Shah, M.S. Nicoloso, and I. de Martino E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer Cancer Cell 13 2008 272 286
    • (2008) Cancer Cell , vol.13 , pp. 272-286
    • Petrocca, F.1    Visone, R.2    Onelli, M.R.3    Shah, M.H.4    Nicoloso, M.S.5    De Martino, I.6
  • 29
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • K.D. Taganov, M.P. Boldin, K.J. Chang, and D. Baltimore NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses Proc Natl Acad Sci USA 103 2006 12481 12486
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 30
    • 34249819336 scopus 로고    scopus 로고
    • MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
    • J. Tsang, J. Zhu, and A. van Oudenaarden MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals Mol Cell 26 2007 753 767
    • (2007) Mol Cell , vol.26 , pp. 753-767
    • Tsang, J.1    Zhu, J.2    Van Oudenaarden, A.3
  • 32
    • 58149382580 scopus 로고    scopus 로고
    • MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc
    • B.D. Aguda, Y. Kim, M.G. Piper-Hunter, A. Friedman, and C.B. Marsh MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc Proc Natl Acad Sci USA 105 2008 19678 19683
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19678-19683
    • Aguda, B.D.1    Kim, Y.2    Piper-Hunter, M.G.3    Friedman, A.4    Marsh, C.B.5


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