메뉴 건너뛰기




Volumn 31, Issue 5, 2013, Pages 522-530

Insulin-like growth factor pathway: A link between androgen deprivation therapy (ADT), insulin resistance, and disease progression in patients with prostate cancer?

Author keywords

Androgen deprivation therapy; Castration resistant; Insulin resistance; Insulin like growth factor; Prostate cancer

Indexed keywords

ANTINEOPLASTIC AGENT; CIXUTUMUMAB; DOCETAXEL; FIGITUMUMAB; GANITUMAB; MITOXANTRONE; NORDIHYDROGUAREACETIC ACID; SOMATOMEDIN; UNCLASSIFIED DRUG;

EID: 84874102233     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2011.05.001     Document Type: Review
Times cited : (25)

References (61)
  • 1
    • 33748474608 scopus 로고    scopus 로고
    • Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy
    • Braga-Basaria M., Dobs A.S., Muller D.C., et al. Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy. J Clin Oncol 2006, 24:3979-3983.
    • (2006) J Clin Oncol , vol.24 , pp. 3979-3983
    • Braga-Basaria, M.1    Dobs, A.S.2    Muller, D.C.3
  • 2
    • 31544440178 scopus 로고    scopus 로고
    • Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen deprivation therapy
    • Basaria S., Muller D.C., Carducci M.A., et al. Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen deprivation therapy. Cancer 2006, 106:581-588.
    • (2006) Cancer , vol.106 , pp. 581-588
    • Basaria, S.1    Muller, D.C.2    Carducci, M.A.3
  • 3
    • 0037326906 scopus 로고    scopus 로고
    • Testosterone suppression in men with prostate cancer leads to an increase in arterial stiffness and hyperinsulinaemia
    • Dockery F., Bulpitt C.J., Agarwal S., et al. Testosterone suppression in men with prostate cancer leads to an increase in arterial stiffness and hyperinsulinaemia. Clin Sci (Lond) 2003, 104:195-201.
    • (2003) Clin Sci (Lond) , vol.104 , pp. 195-201
    • Dockery, F.1    Bulpitt, C.J.2    Agarwal, S.3
  • 4
    • 0034847215 scopus 로고    scopus 로고
    • The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer
    • Smith J.C., Bennett S., Evans L.M., et al. The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab 2001, 86:4261-4267.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4261-4267
    • Smith, J.C.1    Bennett, S.2    Evans, L.M.3
  • 5
    • 0036173823 scopus 로고    scopus 로고
    • Changes in body composition during androgen deprivation therapy for prostate cancer
    • Smith M.R., Finkelstein J.S., McGovern F.J., et al. Changes in body composition during androgen deprivation therapy for prostate cancer. J Clin Endocrinol Metab 2002, 87:599-603.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 599-603
    • Smith, M.R.1    Finkelstein, J.S.2    McGovern, F.J.3
  • 6
    • 33646029746 scopus 로고    scopus 로고
    • Insulin sensitivity during combined androgen blockade for prostate cancer
    • Smith M.R., Lee H., Nathan D.M. Insulin sensitivity during combined androgen blockade for prostate cancer. J Clin Endocrinol Metab 2006, 91:1305-1308.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1305-1308
    • Smith, M.R.1    Lee, H.2    Nathan, D.M.3
  • 7
    • 33749058933 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer
    • Keating N.L., O'Malley J., Smith M.R. Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J Clin Oncol 2006, 24:4448-4455.
    • (2006) J Clin Oncol , vol.24 , pp. 4448-4455
    • Keating, N.L.1    O'Malley, J.2    Smith, M.R.3
  • 8
    • 70349251631 scopus 로고    scopus 로고
    • Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer
    • Albanes D., Weinstein S.J., Wright M.E., et al. Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer. J Natl Cancer Inst 2009, 101:1272-1279.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1272-1279
    • Albanes, D.1    Weinstein, S.J.2    Wright, M.E.3
  • 9
    • 0028952799 scopus 로고
    • Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada
    • Whittemore A.S., Kolonel L.N., Wu A.H., et al. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995, 87:652-661.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 652-661
    • Whittemore, A.S.1    Kolonel, L.N.2    Wu, A.H.3
  • 10
    • 0037248713 scopus 로고    scopus 로고
    • Insulin resistance and prostate cancer risk
    • Hsing A.W., Gao Y.T., Chua S., et al. Insulin resistance and prostate cancer risk. J Natl Cancer Inst 2003, 95:67-71.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 67-71
    • Hsing, A.W.1    Gao, Y.T.2    Chua, S.3
  • 11
    • 0034653160 scopus 로고    scopus 로고
    • Anthropometry in relation to prostate cancer risk in The Netherlands Cohort Study
    • Schuurman A.G., Goldbohm R.A., Dorant E., et al. Anthropometry in relation to prostate cancer risk in The Netherlands Cohort Study. Am J Epidemiol 2000, 151:541-549.
    • (2000) Am J Epidemiol , vol.151 , pp. 541-549
    • Schuurman, A.G.1    Goldbohm, R.A.2    Dorant, E.3
  • 12
    • 0034525928 scopus 로고    scopus 로고
    • Body size and prostate cancer: A population-based case-control study in China
    • Hsing A.W., Deng J., Sesterhenn I.A., et al. Body size and prostate cancer: A population-based case-control study in China. Cancer Epidemiol Biomarkers Prev 2000, 9:1335-1341.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 1335-1341
    • Hsing, A.W.1    Deng, J.2    Sesterhenn, I.A.3
  • 13
    • 34547736129 scopus 로고    scopus 로고
    • Risk factors for prostate cancer incidence and progression in the health professionals follow up study
    • Giovannucci E., Liu Y., Platz E.A., et al. Risk factors for prostate cancer incidence and progression in the health professionals follow up study. Int J Cancer 2007, 121:1571-1578.
    • (2007) Int J Cancer , vol.121 , pp. 1571-1578
    • Giovannucci, E.1    Liu, Y.2    Platz, E.A.3
  • 14
    • 11144357623 scopus 로고    scopus 로고
    • Clinical, hemodynamic, anthropometric, metabolic, and insulin profile of men with high-stage and high-grade clinical prostate cancer
    • Hammarsten J., Hogstedt B. Clinical, hemodynamic, anthropometric, metabolic, and insulin profile of men with high-stage and high-grade clinical prostate cancer. Blood Pressure 2004, 13:47-55.
    • (2004) Blood Pressure , vol.13 , pp. 47-55
    • Hammarsten, J.1    Hogstedt, B.2
  • 15
    • 0036138904 scopus 로고    scopus 로고
    • Increased serum insulin associated with increased risk of prostate cancer recurrence
    • Lehrer S., Diamond E.J., Stagger S., et al. Increased serum insulin associated with increased risk of prostate cancer recurrence. Prostate 2002, 50:1-3.
    • (2002) Prostate , vol.50 , pp. 1-3
    • Lehrer, S.1    Diamond, E.J.2    Stagger, S.3
  • 16
    • 27744444278 scopus 로고    scopus 로고
    • Impact of obesity on prostate cancer recurrence after radical prostatectomy: Data from CaPSURE
    • Bassett W.W., Cooperberg M.R., Sadetsky N., et al. Impact of obesity on prostate cancer recurrence after radical prostatectomy: Data from CaPSURE. Journal of Urology 2005, 66:1060-1065.
    • (2005) Journal of Urology , vol.66 , pp. 1060-1065
    • Bassett, W.W.1    Cooperberg, M.R.2    Sadetsky, N.3
  • 17
    • 1442265961 scopus 로고    scopus 로고
    • Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomy
    • Amling C.L., Riffenburgh R.H., Sun L., et al. Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomy. J Clin Oncol 2004, 22:439-445.
    • (2004) J Clin Oncol , vol.22 , pp. 439-445
    • Amling, C.L.1    Riffenburgh, R.H.2    Sun, L.3
  • 18
    • 33947202141 scopus 로고    scopus 로고
    • Obesity is associated with increased risks of prostate cancer metastasis and death after initial cancer diagnosis in middle-aged men
    • Gong Z., Agalliu I., Lin D.W., et al. Obesity is associated with increased risks of prostate cancer metastasis and death after initial cancer diagnosis in middle-aged men. Cancer 2007, 109:1192-1202.
    • (2007) Cancer , vol.109 , pp. 1192-1202
    • Gong, Z.1    Agalliu, I.2    Lin, D.W.3
  • 19
    • 52649084792 scopus 로고    scopus 로고
    • Obesity and positive surgical margins by anatomic location after radical prostatectomy: Results from the Shared Equal Access Regional Cancer Hospital database
    • Jayachandran J., Aronson W.J., Terris M.K., et al. Obesity and positive surgical margins by anatomic location after radical prostatectomy: Results from the Shared Equal Access Regional Cancer Hospital database. BJU Int 2008, 102:964-968.
    • (2008) BJU Int , vol.102 , pp. 964-968
    • Jayachandran, J.1    Aronson, W.J.2    Terris, M.K.3
  • 20
    • 54349083481 scopus 로고    scopus 로고
    • Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: A long-term survival analysis
    • Ma J., Haojie L., Giovannucci E., et al. Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: A long-term survival analysis. Lancet Oncol 2008, 9:1039-1047.
    • (2008) Lancet Oncol , vol.9 , pp. 1039-1047
    • Ma, J.1    Haojie, L.2    Giovannucci, E.3
  • 21
    • 28244481524 scopus 로고    scopus 로고
    • Hyperinsulinaemia: A prospective risk factor for lethal clinical prostate cancer
    • Hammarsten J., Hogstedt B. Hyperinsulinaemia: A prospective risk factor for lethal clinical prostate cancer. Eur J Cancer 2005, 41:2887-2895.
    • (2005) Eur J Cancer , vol.41 , pp. 2887-2895
    • Hammarsten, J.1    Hogstedt, B.2
  • 22
    • 79953328519 scopus 로고    scopus 로고
    • Presence of the metabolic syndrome is associated with shorter time to castration-resistant prostate cancer
    • Flanagan J., Gray P.K., Hahn N., et al. Presence of the metabolic syndrome is associated with shorter time to castration-resistant prostate cancer. Ann Oncol 2011, 22:801-807.
    • (2011) Ann Oncol , vol.22 , pp. 801-807
    • Flanagan, J.1    Gray, P.K.2    Hahn, N.3
  • 23
    • 34648825008 scopus 로고    scopus 로고
    • Inverse correlation between body mass index and clinical outcomes in men with advanced castration-recurrent prostate cancer
    • Halabi S., Ou S., Vogelzang N.J., et al. Inverse correlation between body mass index and clinical outcomes in men with advanced castration-recurrent prostate cancer. Cancer 2007, 110:1478-1484.
    • (2007) Cancer , vol.110 , pp. 1478-1484
    • Halabi, S.1    Ou, S.2    Vogelzang, N.J.3
  • 25
    • 0033713982 scopus 로고    scopus 로고
    • Differential effects of insulin-like growth factor (IGF)-binding protein-3 and its proteolytic fragments on ligand binding, cell surface association, and IGF-I receptor signaling
    • Devi G., Doo-Hyun Y., Rosenfeld R.G., et al. Differential effects of insulin-like growth factor (IGF)-binding protein-3 and its proteolytic fragments on ligand binding, cell surface association, and IGF-I receptor signaling. Endocrinology 2000, 141:4171-4179.
    • (2000) Endocrinology , vol.141 , pp. 4171-4179
    • Devi, G.1    Doo-Hyun, Y.2    Rosenfeld, R.G.3
  • 26
    • 84894511002 scopus 로고
    • Human osteoblast-derived insulin-like growth factor (IGF-I) binding protein-5 stimulates osteoblast mitogenesis and potentiates IGF-I action
    • Andress D.L., Birnbaum R.S. Human osteoblast-derived insulin-like growth factor (IGF-I) binding protein-5 stimulates osteoblast mitogenesis and potentiates IGF-I action. J Biol Chem 1992, 267:467-472.
    • (1992) J Biol Chem , vol.267 , pp. 467-472
    • Andress, D.L.1    Birnbaum, R.S.2
  • 27
    • 0041419377 scopus 로고    scopus 로고
    • Acute in vivo elevation in IGFBP-1 decreases plasma free IGF-I and muscle protein synthesis
    • Lang C.H., Vary T.C., Frost R.A. Acute in vivo elevation in IGFBP-1 decreases plasma free IGF-I and muscle protein synthesis. Endocrinology 2003, 144:3922-3933.
    • (2003) Endocrinology , vol.144 , pp. 3922-3933
    • Lang, C.H.1    Vary, T.C.2    Frost, R.A.3
  • 28
    • 0028169507 scopus 로고
    • Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells
    • Yee D., Jackson J.G., Kozelsky T.W., et al. Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells. Cell Growth Diff 1994, 5:73-77.
    • (1994) Cell Growth Diff , vol.5 , pp. 73-77
    • Yee, D.1    Jackson, J.G.2    Kozelsky, T.W.3
  • 29
    • 0032455855 scopus 로고    scopus 로고
    • Phosphorylated insulin-like growth factor (IGF)-binding protein-1 (IGFBP-1) inhibits while non-phosphorylated IGFBP-1 stimulates IGF-I-induced amino acid uptake by cultured trophoblast cells
    • Yu J., Iwashita M., Kudo Y., et al. Phosphorylated insulin-like growth factor (IGF)-binding protein-1 (IGFBP-1) inhibits while non-phosphorylated IGFBP-1 stimulates IGF-I-induced amino acid uptake by cultured trophoblast cells. Growth Hormone IGF Res 1998, 8:65-70.
    • (1998) Growth Hormone IGF Res , vol.8 , pp. 65-70
    • Yu, J.1    Iwashita, M.2    Kudo, Y.3
  • 30
    • 0030032795 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes
    • Moses A.C., Young S.C., Morrow L.A., et al. Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes 1996, 45:91.
    • (1996) Diabetes , vol.45 , pp. 91
    • Moses, A.C.1    Young, S.C.2    Morrow, L.A.3
  • 31
    • 65549095726 scopus 로고    scopus 로고
    • The role of insulin-like growth factor-1 and its binding proteins in glucose homeostasis and type 2 diabetes
    • Rajpathak S.N., Gunter M.J., Wylie-Rosett J., et al. The role of insulin-like growth factor-1 and its binding proteins in glucose homeostasis and type 2 diabetes. Diabetes Metab Res Rev 2009, 25:3-12.
    • (2009) Diabetes Metab Res Rev , vol.25 , pp. 3-12
    • Rajpathak, S.N.1    Gunter, M.J.2    Wylie-Rosett, J.3
  • 32
    • 0026550016 scopus 로고
    • Differential expression of the insulin-like growth factor binding proteins in spontaneously diabetic rats
    • Luo J., Murphy L.J. Differential expression of the insulin-like growth factor binding proteins in spontaneously diabetic rats. J Mol Endocrinol 1992, 8:155-163.
    • (1992) J Mol Endocrinol , vol.8 , pp. 155-163
    • Luo, J.1    Murphy, L.J.2
  • 33
    • 15944371521 scopus 로고    scopus 로고
    • Sex hormone-binding globulin and insulin-like growth factor-binding protein-1 as indicators of metabolic syndrome, cardiovascular risk, and mortality in elderly men
    • Kalme T., Seppala M., Qiao Q., et al. Sex hormone-binding globulin and insulin-like growth factor-binding protein-1 as indicators of metabolic syndrome, cardiovascular risk, and mortality in elderly men. J Clin Endocrinol Metab 2005, 90:1550-1556.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1550-1556
    • Kalme, T.1    Seppala, M.2    Qiao, Q.3
  • 34
    • 0031808690 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-1 as a marker of the metabolic syndrome-a study in borderline hypertension
    • Lemne C., Brismar K. Insulin-like growth factor binding protein-1 as a marker of the metabolic syndrome-a study in borderline hypertension. Blood Pressure 1998, 7:88-95.
    • (1998) Blood Pressure , vol.7 , pp. 88-95
    • Lemne, C.1    Brismar, K.2
  • 35
    • 39749087521 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-axis, inflammation, and glucose intolerance among older adults
    • Rajpathak S.N., McGinn A.P., Strickler H.D., et al. Insulin-like growth factor (IGF)-axis, inflammation, and glucose intolerance among older adults. Growth Hormone IGF Res 2008, 18:166-173.
    • (2008) Growth Hormone IGF Res , vol.18 , pp. 166-173
    • Rajpathak, S.N.1    McGinn, A.P.2    Strickler, H.D.3
  • 36
    • 0036324156 scopus 로고    scopus 로고
    • Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes
    • Heald A.H., Siddals K.W., Fraser W., et al. Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes. Diabetes 2002, 51:2629-2636.
    • (2002) Diabetes , vol.51 , pp. 2629-2636
    • Heald, A.H.1    Siddals, K.W.2    Fraser, W.3
  • 37
    • 0030059487 scopus 로고    scopus 로고
    • Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)
    • Gibson J.M., Westwood M., Young R.J., et al. Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM). J Clin Endocrinol Metab 1996, 81:860-863.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 860-863
    • Gibson, J.M.1    Westwood, M.2    Young, R.J.3
  • 38
    • 53749097826 scopus 로고    scopus 로고
    • Insulin-like growth factors, their binding proteins, and prostate cancer risk: Analysis of individual patient data from 12 prospective studies
    • Roddam A.W., Allen N.E., Appleby P., et al. Insulin-like growth factors, their binding proteins, and prostate cancer risk: Analysis of individual patient data from 12 prospective studies. Ann Internal Med 2008, 149:461-471.
    • (2008) Ann Internal Med , vol.149 , pp. 461-471
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3
  • 39
    • 0028048974 scopus 로고
    • Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease
    • Cohen P., Peehl D.M., Graves H.C.B., et al. Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease. J Endocrinol 1994, 142:407-415.
    • (1994) J Endocrinol , vol.142 , pp. 407-415
    • Cohen, P.1    Peehl, D.M.2    Graves, H.C.B.3
  • 40
    • 0037125383 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 as predictors of advanced-stage prostate cancer
    • Chan J.M., Meir J.S., Ma J., et al. Insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. J Natl Cancer Inst 2002, 94:1099-1106.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1099-1106
    • Chan, J.M.1    Meir, J.S.2    Ma, J.3
  • 41
    • 64249111139 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor peptides and prostate cancer risk: A systematic review and meta-analysis.
    • Rowlands M, Gunnell D, Harris R, et al. Circulating insulin-like growth factor peptides and prostate cancer risk: A systematic review and meta-analysis. Int J Cancer 124:2416-29.
    • Int J Cancer , vol.124 , pp. 2416-29
    • Rowlands, M.1    Gunnell, D.2    Harris, R.3
  • 42
    • 0035881876 scopus 로고    scopus 로고
    • In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR)
    • Nickerson T., Chang F., Lorimer D., et al. In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR). Cancer Res 2001, 61:6276-6280.
    • (2001) Cancer Res , vol.61 , pp. 6276-6280
    • Nickerson, T.1    Chang, F.2    Lorimer, D.3
  • 43
    • 0037092971 scopus 로고    scopus 로고
    • Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
    • Hellawell G.O., Turner G.D.H., Davies D.R., et al. Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res 2002, 62:2942-2950.
    • (2002) Cancer Res , vol.62 , pp. 2942-2950
    • Hellawell, G.O.1    Turner, G.D.H.2    Davies, D.R.3
  • 44
    • 9244242088 scopus 로고    scopus 로고
    • Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model
    • Krueckl S.L., Sikes R.A., Edlund N.M., et al. Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res 2004, 64:8620-8629.
    • (2004) Cancer Res , vol.64 , pp. 8620-8629
    • Krueckl, S.L.1    Sikes, R.A.2    Edlund, N.M.3
  • 45
    • 0029937307 scopus 로고    scopus 로고
    • Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo
    • Burfeind P., Chernicky C.L., Rininsland F., et al. Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo. Proc Natl Acad Sci U S A 1996, 93:7263-7268.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 7263-7268
    • Burfeind, P.1    Chernicky, C.L.2    Rininsland, F.3
  • 46
    • 4344591505 scopus 로고    scopus 로고
    • Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors
    • Goya M., Miyamoto S., Nagai K., et al. Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors. Cancer Res 2004, 64:6252-6258.
    • (2004) Cancer Res , vol.64 , pp. 6252-6258
    • Goya, M.1    Miyamoto, S.2    Nagai, K.3
  • 47
    • 9244242088 scopus 로고    scopus 로고
    • Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model
    • Krueckl S.L., Sikes R.A., Edlund N.M., et al. Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res 2004, 64:8620-8629.
    • (2004) Cancer Res , vol.64 , pp. 8620-8629
    • Krueckl, S.L.1    Sikes, R.A.2    Edlund, N.M.3
  • 48
    • 0033589283 scopus 로고    scopus 로고
    • Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays
    • Bubendorf L., Kolmer M., Kononen J., et al. Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays. J Natl Cancer Inst 1999, 91:1758-1764.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1758-1764
    • Bubendorf, L.1    Kolmer, M.2    Kononen, J.3
  • 49
    • 0030071847 scopus 로고    scopus 로고
    • Immunohistochemical localization of insulin-like growth factor binding proteins 2 and 3 in prostate tissue: Clinical correlations
    • Thrasher B., Tennant M., Twomey P., et al. Immunohistochemical localization of insulin-like growth factor binding proteins 2 and 3 in prostate tissue: Clinical correlations. J Urol 1996, 155:999-1003.
    • (1996) J Urol , vol.155 , pp. 999-1003
    • Thrasher, B.1    Tennant, M.2    Twomey, P.3
  • 50
    • 0038756444 scopus 로고    scopus 로고
    • Castration-induced increases in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors
    • Kiyama S., Morrison K., Zellweger T., et al. Castration-induced increases in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors. Cancer Res 2003, 63:3575-3584.
    • (2003) Cancer Res , vol.63 , pp. 3575-3584
    • Kiyama, S.1    Morrison, K.2    Zellweger, T.3
  • 51
    • 0031897867 scopus 로고    scopus 로고
    • Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer
    • Figueroa J., De Raad S., Tadlock L., et al. Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer. J Urol 1998, 159:1379-1383.
    • (1998) J Urol , vol.159 , pp. 1379-1383
    • Figueroa, J.1    De Raad, S.2    Tadlock, L.3
  • 52
    • 0034213320 scopus 로고    scopus 로고
    • Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models
    • Miyake H., Pollak M., Gleave M.E. Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models. Cancer Res 2000, 60:3058-3064.
    • (2000) Cancer Res , vol.60 , pp. 3058-3064
    • Miyake, H.1    Pollak, M.2    Gleave, M.E.3
  • 53
    • 35648935091 scopus 로고    scopus 로고
    • Regulation of global gene expression in the bone marrow microenvironment by androgen: Androgen ablation increases insulin-like growth factor binding protein-5 expression
    • Xu C., Graf L.F., Fazli L., et al. Regulation of global gene expression in the bone marrow microenvironment by androgen: Androgen ablation increases insulin-like growth factor binding protein-5 expression. Prostate 2007, 67:1621-1629.
    • (2007) Prostate , vol.67 , pp. 1621-1629
    • Xu, C.1    Graf, L.F.2    Fazli, L.3
  • 54
    • 33847374107 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer
    • Ryan C.J., Hagg C.M., Simko J., et al. Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer. Urol Oncol 2007, 25:134-140.
    • (2007) Urol Oncol , vol.25 , pp. 134-140
    • Ryan, C.J.1    Hagg, C.M.2    Simko, J.3
  • 55
    • 84879462698 scopus 로고    scopus 로고
    • A phase II study of cixutumumab (IMC-A12), a monoclonal antibody (MAb) against the insulin-like growth factor 1 receptor (IGF-IR), monotherapy in metastatic castration-resistant prostate cancer (mCRPC): Feasibility of every 3-week dosing and updated results. Proceedings of the ASCO Genitourinary Cancers Symposium, March 2010, San Francisco, CA. [Abstract].
    • Higano CS, Alumkal JJ, Ryan CJ, et al. A phase II study of cixutumumab (IMC-A12), a monoclonal antibody (MAb) against the insulin-like growth factor 1 receptor (IGF-IR), monotherapy in metastatic castration-resistant prostate cancer (mCRPC): Feasibility of every 3-week dosing and updated results. Proceedings of the ASCO Genitourinary Cancers Symposium, March 2010, San Francisco, CA. [Abstract].
    • Higano, C.S.1    Alumkal, J.J.2    Ryan, C.J.3
  • 56
    • 84879460260 scopus 로고    scopus 로고
    • Phase I trial involving the pharmacodynamic (PD) study of circulating tumor cells, of CP-751,871 (C), a monoclonal antibody against the insulin-like growth factor 1 receptor (IGF-1R), with docetaxel (D) in patients (p) with advanced cancer. Proceedings of the ASCO Annual Meeting, June, Atlanta, GA. [Abstract].
    • Attard G, Fong PC, Molife R, et al. Phase I trial involving the pharmacodynamic (PD) study of circulating tumor cells, of CP-751,871 (C), a monoclonal antibody against the insulin-like growth factor 1 receptor (IGF-1R), with docetaxel (D) in patients (p) with advanced cancer. Proceedings of the ASCO Annual Meeting, June 2006, Atlanta, GA. [Abstract].
    • (2006)
    • Attard, G.1    Fong, P.C.2    Molife, R.3
  • 57
    • 38549094538 scopus 로고    scopus 로고
    • A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer
    • Ryan C.J., Harzstark A.H., Rosenberg J., et al. A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer. BJUI 2008, 101:436-439.
    • (2008) BJUI , vol.101 , pp. 436-439
    • Ryan, C.J.1    Harzstark, A.H.2    Rosenberg, J.3
  • 58
    • 48749104761 scopus 로고    scopus 로고
    • Inhibitory effects of nordihydroguareacetic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells
    • Ryan C.J., Zavodovskaya M., Youngren J.F., et al. Inhibitory effects of nordihydroguareacetic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells. The Prostate 2008, 68:1232-1240.
    • (2008) The Prostate , vol.68 , pp. 1232-1240
    • Ryan, C.J.1    Zavodovskaya, M.2    Youngren, J.F.3
  • 59
    • 73349099049 scopus 로고    scopus 로고
    • Phase I, Pharmacokinetic, and Pharmacodynamic Study of AMG 479, a Fully Human Monoclonal Antibody to Insulin-Like Growth Factor Receptor 1
    • Tolcher A.W., Sarantopoulos J., Patnaik A., et al. Phase I, Pharmacokinetic, and Pharmacodynamic Study of AMG 479, a Fully Human Monoclonal Antibody to Insulin-Like Growth Factor Receptor 1. J Clin Oncol 2009, 27:5800-5807.
    • (2009) J Clin Oncol , vol.27 , pp. 5800-5807
    • Tolcher, A.W.1    Sarantopoulos, J.2    Patnaik, A.3
  • 60
    • 80053504259 scopus 로고    scopus 로고
    • Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients
    • [Epub ahead of print]
    • He X.X., Tu S.M., Lee M.H., et al. Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients. Ann Oncol 2011 March 17, [Epub ahead of print].
    • (2011) Ann Oncol
    • He, X.X.1    Tu, S.M.2    Lee, M.H.3
  • 61
    • 4844219655 scopus 로고    scopus 로고
    • Rosiglitazone versus placebo for men with prostate carcinoma and a rising serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy
    • Smith M.R., Manola J., Kaufman D.S., et al. Rosiglitazone versus placebo for men with prostate carcinoma and a rising serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy. Cancer 2004, 101:1569-1574.
    • (2004) Cancer , vol.101 , pp. 1569-1574
    • Smith, M.R.1    Manola, J.2    Kaufman, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.