Dramatic resolution of choroidal neovascular abnormalities after single aflibercept injection following years of ranibizumab use

JAMA Ophthalmology

Volumn 131, Issue 2, 2013, Pages 260-262

  Chaikitmongkol, Voraporn ^a,b   Bressler, Neil M ^b  

^a THAMMASAT UNIVERSITY   (Thailand)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; BEVACIZUMAB; FLUORESCEIN; RANIBIZUMAB; VERTEPORFIN;

AGED; ANTIANGIOGENIC THERAPY; BLURRED VISION; CASE REPORT; CLINICAL FEATURE; DRUG EFFICACY; DRUG RESPONSE; HUMAN; LASER COAGULATION; LETTER; MACULAR THICKNESS; MALE; OPTICAL COHERENCE TOMOGRAPHY; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RETINA DETACHMENT; RETINA FLUORESCEIN ANGIOGRAPHY; SINGLE DRUG DOSE; SUBRETINAL NEOVASCULARIZATION; VISUAL ACUITY;

AGED; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; CAPILLARY PERMEABILITY; CHOROIDAL NEOVASCULARIZATION; FLUORESCEIN ANGIOGRAPHY; HUMANS; INTRAVITREAL INJECTIONS; MACULAR EDEMA; MALE; PHOTOCHEMOTHERAPY; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; REMISSION INDUCTION; TOMOGRAPHY, OPTICAL COHERENCE; VISUAL ACUITY;

EID: 84874101310     PISSN: 21686165     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaophthalmol.2013.1733     Document Type: Letter

References (4)

1. US Food and Drug Administration. Eylea. http://www.accessdata.fda.gov/ scripts/cder/drugsatfda/. Accessed August 29, 2012.
2. Stewart MW, Rosenfeld PJ. Predicted biological activity of intravitreal VEGF Trap. Br J Ophthalmol. 2008;92(5):667-668.
3. Holash J, Davis S, Papadopoulos N, et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci U S A. 2002;99(17):11393-11398.
4. Zweifel SA, Engelbert M, Laud K, Margolis R, Spaide RF, Freund KB. Outer retinal tubulation: a novel optical coherence tomography finding. Arch Ophthalmol. 2009;127(12):1596-1602.