Improved assay to detect Plasmodium falciparum using an uninterrupted, semi-nested PCR and quantitative lateral flow analysis

Malaria Journal

Volumn 12, Issue 1, 2013, Pages

  Ongagna Yhombi, Serge Y ^a,e   Corstjens, Paul ^b   Geva, Eran ^a   Abrams, William R ^a   Barber, Cheryl A ^a   Malamud, Daniel ^a   Mharakurwa, Sungano ^c,d  

^a NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d Malaria Institute at Macha   (Zambia)

^e UNIVERSITY OF DELAWARE   (United States)

Author keywords

Detection; Lateral flow; Malaria; PCR; Plasmodium falciparum; Semi nested PCR

Indexed keywords

DIHYDROFOLATE REDUCTASE;

AMPLICON; ARTICLE; FLOW MEASUREMENT; MALARIA; MICROFLUIDIC ANALYSIS; NON INVASIVE PROCEDURE; NUCLEIC ACID AMPLIFICATION; PARASITEMIA; PLASMODIUM FALCIPARUM; POINT OF CARE TESTING; POLYMERASE CHAIN REACTION; SALIVA; SENSITIVITY AND SPECIFICITY; TECHNOLOGY; UP CONVERTING PHOSPHOR REPORTER TECHNOLOGY;

HUMANS; MALARIA, FALCIPARUM; PARASITE LOAD; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 84874100585     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-12-74     Document Type: Article

References (38)

1. WHO, World Malaria Report 2011 Geneva: World Health Organization 2011
2. Update on rapid diagnostic testing for malaria. Murray CK, Gasser RA Jr, Magill AJ, Miller RS, Clin Microbiol Rev 2008 21 97 110 10.1128/CMR.00035-07 18202438 (Pubitemid 351160011)
3. Comparison of HRP2- and pLDH-based rapid diagnostic tests for malaria with longitudinal follow-up in Kampala, Uganda. Hopkins H, Kambale W, Kamya MR, Staedke SG, Dorsey G, Rosenthal PJ, Am J Trop Med Hyg 2007 76 1092 1097 17556616 (Pubitemid 351837871)
4. Non-microscopic method for malaria diagnosis using OptiMAL IT, a second-generation dipstick for malaria pLDH antigen detection. Moody AH, Chiodini PL, Br J Biomed Sci 2002 59 228 231 12572958 (Pubitemid 38101998)
5. Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria. Ashley EA, Touabi M, Ahrer M, Hutagalung R, Htun K, Luchavez J, Dureza C, Proux S, Leimanis M, Lwin MM, Malar J 2009 8 241 10.1186/1475-2875-8-241 19860920
6. Rapid diagnostic tests for malaria diagnosis in the Peruvian Amazon: impact of pfhrp2 gene deletions and cross-reactions. Maltha J, Gamboa D, Bendezu J, Sanchez L, Cnops L, Gillet P, Jacobs J, PLoS One 2012 7 43094 10.1371/journal.pone.0043094 22952633
7. Test characteristics of two rapid antigen detection tests (SD FK50 and SD FK60) for the diagnosis of malaria in returned travellers. Van der Palen M, Gillet P, Bottieau E, Cnops L, Van Esbroeck M, Jacobs J, Malar J 2009 8 90 10.1186/1475-2875-8-90 19416497
8. Post treatment sensitivity studies with the ParaSight-F test for malaria diagnosis in Zimbabwe. Mharakurwa S, Shiff CJ, Acta Trop 1997 66 61 67 10.1016/S0001-706X(97)00674-8 9227798 (Pubitemid 27285945)
9. Adaptive changes in malaria transmission during scaled up interventions in Southern Zambia. Mharakurwa S, Siame M, Thuma P, American Society for Tropical Medicine & Hygiene 60th Annual Meeting. Philadelphia, Pennsylvania, USA 2011 23332563
10. Nested PCR analysis of Plasmodium parasites. Snounou G, Singh B, Methods Mol Med 2002 72 189 203 12125116
11. PCR detection of Plasmodium falciparum in human urine and saliva samples. Mharakurwa S, Simoloka C, Thuma PE, Shiff CJ, Sullivan DJ, Malar J 2006 5 103 10.1186/1475-2875-5-103 17092335 (Pubitemid 44785732)
12. PCR as a confirmatory technique for laboratory diagnosis of malaria. Johnston SP, Pieniazek NJ, Xayavong MV, Slemenda SB, Wilkins PP, da Silva AJ, J Clin Microbiol 2006 44 1087 1089 10.1128/JCM.44.3.1087-1089.2006 16517900
13. Comparative detection of Plasmodium vivax and Plasmodium falciparum DNA in saliva and urine samples from symptomatic malaria patients in a low endemic area. Buppan P, Putaporntip C, Pattanawong U, Seethamchai S, Jongwutiwes S, Malar J 2010 9 72 10.1186/1475-2875-9-72 20214828
14. Only viable parasites are detected by PCR following clearance of rodent malarial infections by drug treatment or immune responses. Jarra W, Snounou G, Infect Immun 1998 66 3783 3787 9673262 (Pubitemid 28347837)
15. Informed decision-making before changing to RDT: a comparison of microscopy, rapid diagnostic test and molecular techniques for the diagnosis and identification of malaria parasites in Kassala, eastern Sudan. Osman MM, Nour BY, Sedig MF, De Bes L, Babikir AM, Mohamedani AA, Mens PF, Trop Med Int Health 2010 15 1442 1448 10.1111/j.1365-3156.2010.02659.x 20973878
16. A genus- and species-specific nested polymerase chain reaction malaria detection assay for epidemiologic studies. Singh B, Bobogare A, Cox-Singh J, Snounou G, Abdullah MS, Rahman HA, Am J Trop Med Hyg 1999 60 687 692 10348249 (Pubitemid 29233131)
17. Development of a single tube hemi-nested PCR for genus-specific detection of Plasmodium in oligoparasitemic patients. Montenegro LM, Montenegro RA, Lima AS, Carvalho AB, Schindler HC, Abath FG, Trans R Soc Trop Med Hyg 2004 98 619 625 10.1016/j.trstmh.2003.11.011 15289099 (Pubitemid 39345163)
18. Real-time PCR assay and rapid diagnostic tests for the diagnosis of clinically suspected malaria patients in Bangladesh. Alam MS, Mohon AN, Mustafa S, Khan WA, Islam N, Karim MJ, Khanum H, Sullivan DJ Jr, Haque R, Malar J 2011 10 175 10.1186/1475-2875-10-175 21703009
19. Development of a real-time PCR assay for detection of Plasmodium falciparum, Plasmodium vivax and Plasmodium ovale for routine clinical diagnosis. Perandin F, Manca N, Calderaro A, Piccolo G, Galati L, Ricci L, Medici MC, Arcangeletti MC, Snounou G, Dettori G, Chezzi C, J Clin Microbiol 2004 42 1214 1219 10.1128/JCM.42.3.1214-1219.2004 15004078 (Pubitemid 38332850)
20. Real-time PCR in clinical microbiology: applications for routine laboratory testing. Espy MJ, Uhl JR, Sloan LM, Buckwalter SP, Jones MF, Vetter EA, Yao JD, Wengenack NL, Rosenblatt JE, Cockerill FR 3rd, Smith TF, Clin Microbiol Rev 2006 19 165 256 10.1128/CMR.19.1.165-256.2006 16418529 (Pubitemid 43158452)
21. Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV, and TB). Corstjens PL, Chen Z, Zuiderwijk M, Bau HH, Abrams WR, Malamud D, Sam Niedbala R, Tanke HJ, Ann N Y Acad Sci 2007 1098 437 445 10.1196/annals.1384.016 17435148 (Pubitemid 47092537)
22. A microfluidic system for saliva-based detection of infectious diseases. Chen Z, Mauk MG, Wang J, Abrams WR, Corstjens PL, Niedbala RS, Malamud D, Bau HH, Ann N Y Acad Sci 2007 1098 429 436 10.1196/annals.1384.024 17435147 (Pubitemid 47092545)
23. Development of a microfluidic device for detection of pathogens in oral samples using upconverting phosphor technology (UPT). Abrams WR, Barber CA, McCann K, Tong G, Chen Z, Mauk MG, Wang J, Volkov A, Bourdelle P, Corstjens PL, Zuiderwijk M, Kardos K, Li S, Tanke HJ, Sam Niedbala R, Malamud D, Bau H, Ann N Y Acad Sci 2007 1098 375 388 10.1196/annals.1384.020 17435143 (Pubitemid 47092541)
24. Point-of-care diagnostics for infectious diseases. Corstjens PLA, Malamud D, Salivary Diagnostics Wiley-Blackwell Publisher, Wong DT, 136 149
25. Malamud D, Niedbala RS, New York Academy of Sciences. Oral-based diagnostics Boston, Mass: Published by Blackwell Pub. on behalf of the New York Academy of Sciences 2007
26. Point detection of pathogens in oral samples. Malamud D, Bau H, Niedbala S, Corstjens P, Adv Dent Res 2005 18 12 16 10.1177/154407370501800104 15998938
27. Infrared up-converting phosphors for bioassays. Corstjens PL, Li S, Zuiderwijk M, Kardos K, Abrams WR, Niedbala RS, Tanke HJ, IEE Proc Nanobiotechnol 2005 152 64 72 10.1049/ip-nbt:20045014 16441160 (Pubitemid 40609587)
28. NIH Image to ImageJ: 25 years of image analysis. Schneider CA, Rasband WS, Eliceiri KW, Nat Methods 2012 9 671 675 10.1038/nmeth.2089 22930834
29. The importance of sensitive detection of malaria parasites in the human and insect hosts in epidemiological studies as shown by the analysis of field samples from Guinea-Bissau. Snounou G, Pinheiro L, Goncalves A, Fonseca L, Dias F, Brown KN, do Rosario V, Trans R Soc Trop Med Hyg 1993 87 649 653 10.1016/0035-9203(93)90274-T 8296364
30. Identification of the four human malaria parasite species in field samples by the polymerase chain reaction and detection of a high prevalence of mixed infections. Snounou G, Viriyakosol S, Jarra W, Thaithong S, Brown KN, Mol Biochem Parasitol 1993 58 283 292 10.1016/0166-6851(93)90050-8 8479452
31. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Snounou G, Viriyakosol S, Zhu XP, Jarra W, Pinheiro L, Do Rosario VE, Thaithong S, Brown KN, Mol Biochem Parasitol 1993 61 315 320 10.1016/0166-6851(93)90077-B 8264734
32. The importance of sensitive detection of malaria parasites in the human and insect hosts in epidemiological studies, as shown by the analysis of field samples from Guinea Bissau. Snounou G, Pinheiro L, Goncalves A, Fonseca L, Dias F, Brown KN, Do Rosario VE, Trans R Soc Trop Med Hyg 1993 87 649 653 10.1016/0035-9203(93)90274-T 8296364
33. Detection of malaria in Malaysia by nested polymerase chain reaction amplification of dried blood spots on filter papers. Singh B, Cox-Singh J, Miller AO, Abdullah MS, Snounou G, Rahman HA, Trans R Soc Trop Med Hyg 1996 90 519 521 10.1016/S0035-9203(96)90302-8 8944260 (Pubitemid 26356629)
34. A comparative analysis of PCR-based detection methods for avaian malaria. Richard FA, Sehgal RN, Jones HI, Smith TB, J Parasitol 2002 88 819 822 12197145 (Pubitemid 34875720)
35. Use of up-converting phosphor reporters in lateral-flow assays to detect specific nucleic acid sequences: a rapid, sensitive DNA test to identify human papillomavirus type 16 infection. Corstjens P, Zuiderwijk M, Brink A, Li S, Feindt H, Niedbala RS, Tanke H, Clin Chem 2001 47 1885 1893 11568115 (Pubitemid 32881216)
36. Real-time PCR versus conventional PCR for malaria parasite detection in low-grade parasitemia. Gama BE, Silva-Pires Fdo E, Lopes MN, Cardoso MA, Britto C, Torres KL, de Mendonca Lima L, de Souza JM, Daniel-Ribeiro CT, Ferreira-da-Cruz Mde F, Exp Parasitol 2007 116 427 432 10.1016/j.exppara.2007. 02.011 17433301 (Pubitemid 46856423)
37. Development of a generic microfluidic device for simultaneous detection of antibodies and nucleic acids in oral fluids. Chen Z, Abrams WR, Geva E, Dood CJ, González JM, Tanke HJ, Niedbala RS, Zhou P, Malamud D, Corstjens PLAM, BioMed Research International 2013 2013 12
38. A low-cost microfluidic chip for rapid genotyping of malaria-transmitting mosquitoes. Liu C, Mauk MG, Hart R, Bonizzoni M, Yan G, Bau HH, PLoS One 2012 7 42222 10.1371/journal.pone.0042222 22879919