The importance of the intrauterine environment in shaping the human neonatal epigenome

Epigenomics

Volumn 5, Issue 1, 2013, Pages 1-4

  Novakovic, Boris ^a   Saffery, Richard ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

DNA methylation; environment; epigenetics; fetal programming; in utero

Indexed keywords

CELL DIFFERENTIATION; DIFFERENTIATION; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENETICS; HUMAN; HUMAN DEVELOPMENT; MATERNAL SMOKING; PHENOTYPE; PRIORITY JOURNAL; REVIEW; UTERUS;

CELLULAR MICROENVIRONMENT; EPIGENESIS, GENETIC; HUMANS;

EID: 84874090406     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.12.77     Document Type: Review

References (27)

1. Gluckman PD, Hanson MA, Beedle AS. Early life events and their consequences for later disease: A life history and evolutionary perspective. Am. J. Hum. Biol. 19(1), 1-19 (2007).
2. Waddington CH. Canalization of development and genetic assimilation of acquired characters. Nature 183(4676), 1654-1655 (1959).
3. Sebert S, Sharkey D, Budge H, Symonds ME. The early programming of metabolic health: is epigenetic setting the missing link? Am. J. Clin. Nutr. 94(Suppl. 6), S1953-S1958 (2011).
4. Hogg K, Price EM, Hanna CW, Robinson WP. Prenatal and perinatal environmental influences on the human fetal and placental epigenome. Clin. Pharmacol. Ther. 92(6), 716-726 (2012).
5. Joubert BR Håberg SE, Nilsen RM et al. 450K Epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ. Health Perspect. 120(10), 1425-1431 (2012).
6. Koldovsky O. Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences. Ciba Found. Symp. (70), 147-168 (1979).
7. Barker DJ, Bull AR, Osmond C, Simmonds SJ. Fetal and placental size and risk of hypertension in adult life. BMJ 301(6746), 259-262 (1990).
8. Barker DJ, Osmond C, Simmonds SJ, Wield GA. The relation of small head circumference and thinness at birth to death from cardiovascular disease in adult life. BMJ 306(6875), 422-426 (1993).
9. Osmond C, Barker DJ. Ischaemic heart disease in England and Wales around the year 2000. J. Epidemiol. Community Health 45(1), 71-72 (1991).
10. Barker DJ, Winter PD, Osmond C, Margetts B, Simmonds SJ. Weight in infancy and death from ischaemic heart disease. Lancet 2(8663), 577-580 (1989).
11. Roseboom TJ, van der Meulen JH, Ravelli AC, Osmond C, Barker DJ, Bleker OP. Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview. Mol. Cell. Endocrinol. 185(1-2), 93-98 (2001).
12. Bell JT, Saffery R. The value of twins in epigenetic epidemiology. Int. J. Epidemiol. 41(1), 140-150 (2012).
13. Gordon L, Joo JE, Powell JE et al. Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res. 22(8), 1395-1406 (2012).
14. Gartner K. 2 new aspects in laboratory animal science: "intangible variance" and population biology. Dtsch. Tierarztl. Wochenschr. 89(8), 318-322 (1982).
15. Morgan HD, Sutherland HG, Martin DI, Whitelaw E. Epigenetic inheritance at the agouti locus in the mouse. Nat. Genet. 23(3), 314-318 (1999).
16. Waterland RA, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol. Cell. Biol. 23(15), 5293-5300 (2003).
17. Blewitt ME, Chong S, Whitelaw E. How the mouse got its spots. Trends Genet. 20(11), 550-554 (2004).
18. Ollikainen M, Smith KR, Joo EJ et al. DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum. Mol. Genet. 19(21), 4176-4188 (2010).
19. Pujadas E, Feinberg AP. Regulated noise in the epigenetic landscape of development and disease. Cell 148(6), 1123-1131 (2012).
20. Fan S, Zhang X. CpG island methylation pattern in different human tissues and its correlation with gene expression. Biochem. Biophys. Res. Commun. 383(4), 421-425 (2009).
21. Flanagan JM, Popendikyte V, Pozdniakovaite N et al. Intra-and interindividual epigenetic variation in human germ cells. Am. J. Hum. Genet. 79(1), 67-84 (2006).
22. Rakyan VK, Chong S, Champ ME et al. Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission. Proc. Natl Acad. Sci. USA 100(5), 2538-2543 (2003).
23. Trasler JM. Epigenetics in spermatogenesis. Mol. Cell. Endocrinol. 306(1-2), 33-36 (2009).
24. Guibert S, Forné T, Weber M. Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res. 22(4), 633-641 (2012).
25. Okada Y, Yamagata K, Hong K, Wakayama T, Zhang Y. A role for the elongator complex in zygotic paternal genome demethylation. Nature 463(7280), 554-558 (2010).
26. Tao FB, Hao JH, Huang K et al. Cohort profile: the China-Anhui birth cohort study. Int. J. Epidemiol. doi:10.1093/ije/dys085 (2012) (Epub ahead of print).
27. Jaddoe VW, Mackenbach JP, Moll HA et al. The generation R study: design and cohort profile. Eur. J. Epidemiol. 21(6), 475-484 (2006).