Melamine-induced renal toxicity is mediated by the gut microbiota

Science Translational Medicine

Volumn 5, Issue 172, 2013, Pages

  Jia, Wei ^a,b,c   Zheng, Xiaojiao ^a,b   Zhao, Aihua ^a,b   Xie, Guoxiang ^c   Chi, Yi ^b   Zhao, Linjing ^b   Li, Houkai ^c   Wang, Congrong ^a   Bao, Yuqian ^a   Jia, Weiping ^a   Luther, Mike ^d   Su, Mingming ^d   Nicholson, Jeremy K ^e  

^a Center for Translational Medicine   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^d David H Murdock Research Institute   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYANURIC ACID; MELAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL METABOLISM; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; CONTROLLED STUDY; DEAMINATION; DNA SEQUENCE; FECES ANALYSIS; IN VITRO STUDY; INTESTINE FLORA; KLEBSIELLA; KLEBSIELLA TERRIGENA; MALE; MICROBIAL ACTIVITY; NEPHROLITHIASIS; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; URINARY EXCRETION;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOTRANSFORMATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FECES; GASTROINTESTINAL TRACT; KIDNEY CALCULI; KLEBSIELLA; KLEBSIELLA INFECTIONS; METABOLOMICS; MOLECULAR SEQUENCE DATA; RATS; RATS, WISTAR; RIBOTYPING; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; TIME FACTORS; TRIAZINES;

EID: 84874048883     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3005114     Document Type: Article

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