Long-term outcome of human cord blood-derived hematopoietic progenitor cells in murine lungs

Experimental Lung Research

Volumn 39, Issue 2, 2013, Pages 59-69

  De Paepe, Monique E ^a,b   Mao, Quanfu ^a,b   Chu, Sharon ^a   Padbury, James F ^a,c  

^a WOMEN AND INFANTS HOSPITAL   (United States)

^b BROWN UNIVERSITY   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Alveolar type II cell; Bronchopulmonary dysplasia; Chronic lung disease of newborn; Regeneration; Stem cell

Indexed keywords

CD34 ANTIGEN; FAS LIGAND; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INOCULATION; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS MACROPHAGE; LUNG DEVELOPMENT; LUNG DYSPLASIA; LUNG PARENCHYMA; MORPHOMETRICS; MOUSE; NEWBORN; NONHUMAN; OUTCOME ASSESSMENT; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SHAM PROCEDURE; STEREOMETRY; TOTAL LUNG CAPACITY; TRANSGENIC MOUSE; UMBILICAL CORD BLOOD; VOLUMETRY;

ANIMALS; ANTIGENS, CD34; BRONCHOPULMONARY DYSPLASIA; CELL DIFFERENTIATION; CELL SURVIVAL; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT, NEWBORN; MALE; MICE; MICE, TRANSGENIC; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84874028464     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.3109/01902148.2012.752548     Document Type: Article

References (49)

1. Jobe AH, Bancalari E: Bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2001;163:1723-1729.
2. Husain AN, Siddiqui NH, Stocker JT: Pathology of arrested acinar development in postsurfactant bronchopulmonary dysplasia. Hum Pathol. 1998;29:710-717.
3. Jobe AJ: The new BPD: an arrest of lung development. Pediatr Res. 1999;46:641-643.
4. De Paepe ME,Mao Q, Powell J, Rubin SE, DeKoninck P, Appel N, Dixon M, Gundogan F: Growth of pulmonary microvasculature in ventilated preterm infants. Am J Respir Crit CareMed. 2006;173:204-211.
5. Wong P, Murray C, Louw J, French N, Chambers D: Adult bronchopulmonary dysplasia: computed tomography pulmonary findings. J Med Imaging Radiat Oncol. 2011;55:373-378.
6. Wong PM, Lees AN, Louw J, Lee FY, French N, Gain K, Murray CP, Wilson A, Chambers DC: Emphysema in young adult survivors of moderate-to-severe bronchopulmonary dysplasia. Eur Respir J. 2008;32:321-328.
7. Hargitai B, Szabo V, Hajdu J, Harmath A, Pataki M, Farid P, Papp Z, Szende B: Apoptosis in various organs of preterm infants: histopathologic study of lung, kidney, liver, and brain of ventilated infants. Pediatr Res. 2001;50:110-114.
8. Lukkarinen HP, Laine J, Kaapa PO: Lung epithelial cells undergo apoptosis in neonatal respiratory distress syndrome. Pediatr Res. 2003;53:254-259.
9. May M, Strobel P, Preisshofen T, Seidenspinner S, Marx A, Speer CP: Apoptosis and proliferation in lungs of ventilated and oxygen-treated preterminfants. Eur Respir J. 2004;23:113-121.
10. De PaepeME, Gundavarapu S, Tantravahi U, Pepperell JR,Haley SA, Luks FI,Mao Q: Fas-ligand-induced apoptosis of respiratory epithelial cells causes disruption of postcanalicular alveolar development. Am J Pathol. 2008;173:42-56.
11. Sueblinvong V, Loi R, Eisenhauer PL, Bernstein IM, Suratt BT, Spees JL, Weiss DJ: Derivation of lung epithelium from human cord blood-derived mesenchymal stem cells. Am J Respir Crit Care Med. 2008;177:701-711.
12. Macpherson H, Keir P, Webb S, Samuel K, Boyle S, Bickmore W, Forrester L, Dorin J: Bone marrow-derived SP cells can contribute to the respiratory tract of mice in vivo. J Cell Sci. 2005;118:2441-2450.
13. MacPherson H, Keir PA, Edwards CJ, Webb S, Dorin JR: Following damage, the majority of bone marrow-derived airway cells express an epithelial marker. Respir Res. 2006;7:145.
14. Loi R, Beckett T, Goncz KK, Suratt BT, Weiss DJ: Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells. Am J Respir Crit Care Med. 2006;173:171-179.
15. Yan C, Lian X, Dai Y, Wang X, Qu P, White A, Qin Y, Du H: Gene delivery by the hSP-B promoter to lung alveolar type II epithelial cells in LAL-knockout mice through bone marrow mesenchymal stem cells. Gene Ther. 2007;14:1461-1470.
16. Serikov VB, Popov B, Mikhailov VM, Gupta N, MatthayMA: Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice. Anat Rec (Hoboken). 2007;290:1033-1045.
17. Wong AP, Dutly AE, Sacher A, Lee H, Hwang DM, Liu M, Keshavjee S, Hu J,Waddell TK: Targeted cell replacement with bone marrow cells for airway epithelial regeneration. Am J Physiol Lung Cell Mol Physiol. 2007;293:L740-L752.
18. Bruscia EM, Price JE, Cheng EC,Weiner S, Caputo C, Ferreira EC, Egan ME, Krause DS: Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTRnull mice after bone marrow transplantation. Proc Natl Acad Sci USA. 2006;103:2965-2970.
19. Bruscia EM, Ziegler EC, Price JE, Weiner S, Egan ME, Krause DS: Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice. Stem Cells. 2006;24:2299-2308.
20. Spees JL, Pociask DA, Sullivan DE, Whitney MJ, Lasky JA, Prockop DJ, Brody AR: Engraftment of bone marrow progenitor cells in a rat model of asbestos-induced pulmonary fibrosis. Am J Respir Crit Care Med. 2007;176:385-394.
21. Raoul W, Wagner-Ballon O, Saber G, Hulin A, Marcos E, Giraudier S, Vainchenker W, Adnot S, Eddahibi S, Maitre B: Effects of bone marrow-derived cells on monocrotaline-and hypoxia-induced pulmonary hypertension in mice. Respir Res. 2007;8:8.
22. Weiss DJ, Kolls JK, Ortiz LA, Panoskaltsis-Mortari A, Prockop DJ: Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc. 2008;5:637-667.
23. De Paepe ME, Mao Q, Ghanta S, Hovanesian V, Padbury JF: Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells. Am J Pathol. 2011;178:1329-1339.
24. Aslam M, Baveja R, Liang OD, Fernandez-Gonzalez A, Lee C, Mitsialis SA, Kourembanas S: Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am J Respir Crit Care Med. 2009;180:1122-1130.
25. van Haaften T, Byrne R, Bonnet S, Rochefort GY, Akabutu J, Bouchentouf M, Rey-Parra GJ, Galipeau J, Haromy A, Eaton F, Chen M, Hashimoto K, Abley D, Korbutt G, Archer SL, Thebaud B: Airway delivery ofmesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med. 2009;180:1131-1142.
26. Hansmann G, Fernandez-Gonzalez A, Aslam M, Vitali SH, Martin T, Mitsialis SA, Kourembanas S: Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension. Pulm Circ. 2012;2: 170-181.
27. Chang YS, Oh W, Choi SJ, Sung DK, Kim SY, Choi EY, Kang S, Jin HJ, Yang YS, Park WS: Human umbilical cord bloodderived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats. Cell Transplant. 2009;18:869-886.
28. Alphonse RS, Rajabali S, Thebaud B: Lung injury in preterm neonates: the role and therapeutic potential of stem cells. Antioxid Redox Signal. 2012;17:1013-1040.
29. Nakahata T, Ogawa M: Hemopoietic colony-forming cells in umbilical cord blood with extensive capability to generate mono-and multipotential hemopoietic progenitors. J Clin Invest. 1982;70:1324-1328.
30. Broxmeyer HE, Douglas GW, Hangoc G, Cooper S, Bard J, English D, Arny M, Thomas L, Boyse EA: Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc Natl Acad Sci USA. 1989;86:3828-3832.
31. Erices A, Conget P, Minguell JJ: Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol. 2000;109:235-242.
32. Berger MJ, Adams SD, Tigges BM, Sprague SL, Wang XJ, Collins DP, McKenna DH: Differentiation of umbilical cord blood-derived multilineage progenitor cells into respiratory epithelial cells. Cytotherapy. 2006;8:480-487.
33. Kim JW, Kim SY, Park SY, Kim YM, Kim JM, Lee MH, Ryu HM: Mesenchymal progenitor cells in the human umbilical cord. Ann Hematol. 2004;83:733-738.
34. Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, Prockop DJ, Fibbe WE, Blazar BR: Sarcoma derived from cultured mesenchymal stem cells. Stem Cells. 2007;25:371-379.
35. Wang Y, Huso DL, Harrington J, Kellner J, Jeong DK, Turney J, McNiece IK: Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture. Cytotherapy. 2005;7:509-519.
36. Aguilar S, Nye E, Chan J, Loebinger M, Spencer-Dene B, Fisk N, Stamp G, Bonnet D, Janes SM:Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung. Stem Cells. 2007;25:1586-1594.
37. Buckley RH: Transplantation of hematopoietic stem cells in human severe combined immunodeficiency: longterm outcomes. Immunol Res. 2011;49:25-43.
38. Fritzell JA, Jr., Mao Q, Gundavarapu S, Pasquariello T, Aliotta JM, Ayala A, Padbury JF, De Paepe ME: Fate and effects of adult bone marrow cells in lungs of normoxic and hyperoxic newborn mice. Am J Respir Cell Mol Biol. 2009;40:575-587.
39. De Paepe ME, Haley SA, Lacourse Z, Mao Q: Effects of Fasligand overexpression on alveolar type II cell growth kinetics in perinatal murine lungs. Pediatr Res. 2010;68:57-62.
40. Tichelaar JW, Lu W, Whitsett JA: Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J Biol Chem. 2000;275:11858-11864.
41. De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI: Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004;287:L730-L742.
42. Amy RW, Bowes D, Burri PH, Haines J, Thurlbeck WM: Postnatal growth of the mouse lung. J Anat. 1977;124:131-151.
43. De Paepe ME: Lung growth and development. Thurlbeck's pathology of the lung. In: Churg AM, Myers JL, Tazelaar HD, Wright JL, eds. New York: Thieme Medical Publishers; 2005:39-84.
44. Schormann W, Hammersen FJ, Brulport M, Hermes M, Bauer A, Rudolph C, Schug M, Lehmann T, Nussler A, Ungefroren H, Hutchinson J, Fandrich F, Petersen J, Wursthorn K, Burda MR, Brustle O, Krishnamurthi K, von Mach M, Hengstler JG: Tracking of human cells in mice. Histochem Cell Biol. 2008;130:329-338.
45. De PaepeME, Johnson BD, PapadakisK, Luks FI: Lung growth response after tracheal occlusion in fetal rabbits is gestational age-dependent. Am J Respir Cell Mol Biol. 1999;21:65-76.
46. De Paepe ME, Johnson BD, Papadakis K, Sueishi K, Luks FI: Temporal pattern of accelerated lung growth after tracheal occlusion in the fetal rabbit. Am J Pathol. 1998;152: 179-190.
47. Aherne WA, Dunnill, MS: The estimation of whole organ volume. In: AherneWA, Dunnill MS, eds.Morphometry, London: Edward Arnold Ltd; 1982:10-18.
48. Huang P, Duda DG, Jain RK, Fukumura D: Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB/N mice. Comp Med. 2008;58:253-263.
49. Mahler JF, Stokes W, Mann PC, Takaoka M, Maronpot RR: Spontaneous lesions in aging FVB/N mice. Toxicol Pathol. 1996;24:710-716.