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Volumn 47, Issue 2, 2013, Pages 103-108

Decreased GABAA benzodiazepine binding site densities in postmortem brains of Cloninger type 1 and 2 alcoholics

Author keywords

Alcoholism; Autoradiography; Benzodiazepine; GABA; Globus pallidus; Hippocampus

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; DOPAMINE RECEPTOR; FLUNITRAZEPAM; SEROTONIN RECEPTOR; TRITIUM;

EID: 84874020465     PISSN: 07418329     EISSN: 18736823     Source Type: Journal    
DOI: 10.1016/j.alcohol.2012.12.008     Document Type: Article
Times cited : (11)

References (58)
  • 1
    • 84870465485 scopus 로고
    • American Psychiatric Association, American Psychiatric Press, Washington, DC
    • Diagnostic and Statistical Manual of Mental Disorders 1994, American Psychiatric Association, American Psychiatric Press, Washington, DC. 4rd ed.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 3
    • 78650825589 scopus 로고    scopus 로고
    • A population-specific HTR2B stop codon predisposes to severe impulsivity
    • Bevilacqua L., Doly S., Kaprio J., Yuan Q., Tikkanen R., Paunio T., et al. A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature 2010, 468(7327):1061-1066.
    • (2010) Nature , vol.468 , Issue.7327 , pp. 1061-1066
    • Bevilacqua, L.1    Doly, S.2    Kaprio, J.3    Yuan, Q.4    Tikkanen, R.5    Paunio, T.6
  • 5
    • 0033009422 scopus 로고    scopus 로고
    • Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content
    • Calon F., Morissette M., Goulet M., Grondin R., Blanchet P.J., Bédard P.J., et al. Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content. Neurochemistry International 1999, 35(1):81-91.
    • (1999) Neurochemistry International , vol.35 , Issue.1 , pp. 81-91
    • Calon, F.1    Morissette, M.2    Goulet, M.3    Grondin, R.4    Blanchet, P.J.5    Bédard, P.J.6
  • 6
    • 56049091710 scopus 로고    scopus 로고
    • Behavioral and electrophysiological effects of pallidal GABAB receptor activation and blockade on haloperidol-induced akinesia in rats
    • Chen L., Wang H.T., Han X.H., Li Y.L., Cui Q.L., Xie J.X. Behavioral and electrophysiological effects of pallidal GABAB receptor activation and blockade on haloperidol-induced akinesia in rats. Brain Research 2008, 1244:65-70.
    • (2008) Brain Research , vol.1244 , pp. 65-70
    • Chen, L.1    Wang, H.T.2    Han, X.H.3    Li, Y.L.4    Cui, Q.L.5    Xie, J.X.6
  • 7
    • 0029074084 scopus 로고
    • The psychobiological regulation of social co-operation
    • Cloninger C.R. The psychobiological regulation of social co-operation. Nature Medicine 1995, 1:623-624.
    • (1995) Nature Medicine , vol.1 , pp. 623-624
    • Cloninger, C.R.1
  • 11
    • 39149145477 scopus 로고    scopus 로고
    • Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene
    • Covault J., Gelernter J., Jensen K., Anton R., Kranzler H.R. Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene. Neuropsychopharmacology 2008, 33(4):837-848.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.4 , pp. 837-848
    • Covault, J.1    Gelernter, J.2    Jensen, K.3    Anton, R.4    Kranzler, H.R.5
  • 12
    • 0141829702 scopus 로고    scopus 로고
    • The role of GABAA receptors in mediating the effects of alcohol in the central nervous system
    • Davies M. The role of GABAA receptors in mediating the effects of alcohol in the central nervous system. Journal of Psychiatry and Neuroscience 2003, 28(4):263-274.
    • (2003) Journal of Psychiatry and Neuroscience , vol.28 , Issue.4 , pp. 263-274
    • Davies, M.1
  • 13
    • 66449135069 scopus 로고    scopus 로고
    • The role of GABRA2 in trajectories of externalizing behavior across development and evidence if moderation by parental monitoring
    • Dick D.M., Latendresse S.J., Landsford J.E., Budde J.P., Goate A., Dodge K.A., et al. The role of GABRA2 in trajectories of externalizing behavior across development and evidence if moderation by parental monitoring. Archives of General Psychiatry 2009, 66(6):649-657.
    • (2009) Archives of General Psychiatry , vol.66 , Issue.6 , pp. 649-657
    • Dick, D.M.1    Latendresse, S.J.2    Landsford, J.E.3    Budde, J.P.4    Goate, A.5    Dodge, K.A.6
  • 14
    • 0029876817 scopus 로고    scopus 로고
    • Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy
    • Dodd P.R., Kril J.J., Thomas G.J., Watson W.E., Johnston G.A., Harper C.G. Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy. Brain Research 1996, 710(1-2):215-228.
    • (1996) Brain Research , vol.710 , Issue.1-2 , pp. 215-228
    • Dodd, P.R.1    Kril, J.J.2    Thomas, G.J.3    Watson, W.E.4    Johnston, G.A.5    Harper, C.G.6
  • 15
    • 12144288685 scopus 로고    scopus 로고
    • Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations
    • Edenberg H.J., Dick D.M., Xuei X., Tian H., Almasy L., Bauer L.O., et al. Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. The American Journal of Human Genetics 2004, 74(4):705-714.
    • (2004) The American Journal of Human Genetics , vol.74 , Issue.4 , pp. 705-714
    • Edenberg, H.J.1    Dick, D.M.2    Xuei, X.3    Tian, H.4    Almasy, L.5    Bauer, L.O.6
  • 17
    • 71349086065 scopus 로고    scopus 로고
    • The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence
    • Enoch M.A., Hodgkinson C.A., Yuan Q., Shen P.H., Goldman D., Roy A. The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence. Biological Psychiatry 2010, 67(1):20-27.
    • (2010) Biological Psychiatry , vol.67 , Issue.1 , pp. 20-27
    • Enoch, M.A.1    Hodgkinson, C.A.2    Yuan, Q.3    Shen, P.H.4    Goldman, D.5    Roy, A.6
  • 19
    • 33646708528 scopus 로고    scopus 로고
    • Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis
    • Fehr C., Sander T., Tadic A., Lenzen K.P., Anghelescu I., Klawe C., et al. Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis. Psychiatric Genetics 2006, 16(1):9-17.
    • (2006) Psychiatric Genetics , vol.16 , Issue.1 , pp. 9-17
    • Fehr, C.1    Sander, T.2    Tadic, A.3    Lenzen, K.P.4    Anghelescu, I.5    Klawe, C.6
  • 20
    • 21044443874 scopus 로고    scopus 로고
    • Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652
    • Frankle W.G., Lombardo I., New A.S., Goodman M., Talbot P.S., Huang Y., et al. Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652. The American Journal of Psychiatry 2005, 162(5):915-923.
    • (2005) The American Journal of Psychiatry , vol.162 , Issue.5 , pp. 915-923
    • Frankle, W.G.1    Lombardo, I.2    New, A.S.3    Goodman, M.4    Talbot, P.S.5    Huang, Y.6
  • 21
    • 0024160148 scopus 로고
    • Decrease of benzodiazepine receptors in frontal cortex of alcoholics
    • Freund G., Ballinger W.E. Decrease of benzodiazepine receptors in frontal cortex of alcoholics. Alcohol 1988, 5(4):275-282.
    • (1988) Alcohol , vol.5 , Issue.4 , pp. 275-282
    • Freund, G.1    Ballinger, W.E.2
  • 23
    • 0024559228 scopus 로고
    • Loss of muscarinic and benzodiazepine neuroreceptors from hippocampus of alcohol abusers
    • Freund G., Ballinger W.E. Loss of muscarinic and benzodiazepine neuroreceptors from hippocampus of alcohol abusers. Alcohol 1989, 6:23-31.
    • (1989) Alcohol , vol.6 , pp. 23-31
    • Freund, G.1    Ballinger, W.E.2
  • 24
    • 0029831439 scopus 로고    scopus 로고
    • Positron emission tomographic studies of cerebral benzodiazepine-receptor binding in chronic alcoholics
    • Gilman S., Koeppe R.A., Adams K., Johnson-Greene D., Junck L., Kluin K.J., et al. Positron emission tomographic studies of cerebral benzodiazepine-receptor binding in chronic alcoholics. Annals of Neurology 1996, 40:163-171.
    • (1996) Annals of Neurology , vol.40 , pp. 163-171
    • Gilman, S.1    Koeppe, R.A.2    Adams, K.3    Johnson-Greene, D.4    Junck, L.5    Kluin, K.J.6
  • 25
    • 0031697522 scopus 로고    scopus 로고
    • The role of GABA(A) receptors in the acute and chronic effects of ethanol
    • Grobin A.C., Matthews D.B., Devaud L.L., Morrow A.L. The role of GABA(A) receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berl) 1998, 139(1-2):2-19.
    • (1998) Psychopharmacology (Berl) , vol.139 , Issue.1-2 , pp. 2-19
    • Grobin, A.C.1    Matthews, D.B.2    Devaud, L.L.3    Morrow, A.L.4
  • 26
    • 0032880799 scopus 로고    scopus 로고
    • Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior
    • Hallikainen T., Lachman H.M., Volavka J., Pohjalainen T., Ryynänen O.P., Kauhanen J., et al. Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior. Molecular Psychiatry 1999, 4(4):385-388.
    • (1999) Molecular Psychiatry , vol.4 , Issue.4 , pp. 385-388
    • Hallikainen, T.1    Lachman, H.M.2    Volavka, J.3    Pohjalainen, T.4    Ryynänen, O.P.5    Kauhanen, J.6
  • 27
    • 56349146098 scopus 로고    scopus 로고
    • The globus pallidus sends reward-related signals to the lateral habenula
    • Hong S., Hikosaka O. The globus pallidus sends reward-related signals to the lateral habenula. Neuron 2008, 60(4):720-729.
    • (2008) Neuron , vol.60 , Issue.4 , pp. 720-729
    • Hong, S.1    Hikosaka, O.2
  • 29
    • 0034080696 scopus 로고    scopus 로고
    • Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis
    • Jalan R., Turjanski N., Taylor-Robinson S., Koepp M.J., Richardson M.P., Wilson J.A., et al. Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis. Gut 2000, 46:546-552.
    • (2000) Gut , vol.46 , pp. 546-552
    • Jalan, R.1    Turjanski, N.2    Taylor-Robinson, S.3    Koepp, M.J.4    Richardson, M.P.5    Wilson, J.A.6
  • 31
    • 4644342311 scopus 로고    scopus 로고
    • A role for GABA mechanisms in the motivational effects of alcohol
    • Koob G.F. A role for GABA mechanisms in the motivational effects of alcohol. Biochemical Pharmacology 2004, 68(8):1515-1525.
    • (2004) Biochemical Pharmacology , vol.68 , Issue.8 , pp. 1515-1525
    • Koob, G.F.1
  • 33
    • 33748316516 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment
    • Krystal J.H., Staley J., Mason G., Petrakis I.L., Kaufman J., Harris R.A., et al. Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry 2006, 63(9):957-968.
    • (2006) Archives of General Psychiatry , vol.63 , Issue.9 , pp. 957-968
    • Krystal, J.H.1    Staley, J.2    Mason, G.3    Petrakis, I.L.4    Kaufman, J.5    Harris, R.A.6
  • 36
    • 0031010266 scopus 로고    scopus 로고
    • Zolpidem binding sites on the GABA(A) receptor in brain from human cirrhotic and non-cirrhotic alcoholics
    • Lewohl J.M., Crane D.I., Dodd P.R. Zolpidem binding sites on the GABA(A) receptor in brain from human cirrhotic and non-cirrhotic alcoholics. European Journal of Pharmacology 1997, 326(2-3):265-272.
    • (1997) European Journal of Pharmacology , vol.326 , Issue.2-3 , pp. 265-272
    • Lewohl, J.M.1    Crane, D.I.2    Dodd, P.R.3
  • 38
    • 0034310739 scopus 로고    scopus 로고
    • Role of the GABA(A)Abeta2, GABA(A)alpha6, GABA(A)alpha1 and GABA(A)gamma2 receptor subunit genes cluster in drug responses and the development of alcohol dependence
    • Loh E.W., Ball D. Role of the GABA(A)Abeta2, GABA(A)alpha6, GABA(A)alpha1 and GABA(A)gamma2 receptor subunit genes cluster in drug responses and the development of alcohol dependence. Neurochemistry International 2000, 37(5-6):413-423.
    • (2000) Neurochemistry International , vol.37 , Issue.5-6 , pp. 413-423
    • Loh, E.W.1    Ball, D.2
  • 39
    • 0032496340 scopus 로고    scopus 로고
    • Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population
    • Long J.C., Knowler W.C., Hanson R.L., Robin R.W., Urbanek M., Moore E., et al. Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population. American Journal of Medical Genetics 1998, 81(3):216-221.
    • (1998) American Journal of Medical Genetics , vol.81 , Issue.3 , pp. 216-221
    • Long, J.C.1    Knowler, W.C.2    Hanson, R.L.3    Robin, R.W.4    Urbanek, M.5    Moore, E.6
  • 40
    • 0036212571 scopus 로고    scopus 로고
    • Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: a whole-hemisphere autoradiography study
    • Mantere T., Tupala E., Hall H., Särkioja T., Bergström K., Tiihonen J. Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: a whole-hemisphere autoradiography study. The American Journal of Psychiatry 2002, 159(4):599-606.
    • (2002) The American Journal of Psychiatry , vol.159 , Issue.4 , pp. 599-606
    • Mantere, T.1    Tupala, E.2    Hall, H.3    Särkioja, T.4    Bergström, K.5    Tiihonen, J.6
  • 41
    • 1842328604 scopus 로고    scopus 로고
    • Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors
    • Mihic S.J., Ye Q., Wick M.J., Koltchine V.V., Krasowski M.D., Finn S.E., et al. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature 1997, 389(6649):385-389.
    • (1997) Nature , vol.389 , Issue.6649 , pp. 385-389
    • Mihic, S.J.1    Ye, Q.2    Wick, M.J.3    Koltchine, V.V.4    Krasowski, M.D.5    Finn, S.E.6
  • 42
    • 33748925413 scopus 로고    scopus 로고
    • GABA(A) receptor diversity and pharmacology
    • Möhler H. GABA(A) receptor diversity and pharmacology. Cell and Tissue Research 2006, 326(2):505-516.
    • (2006) Cell and Tissue Research , vol.326 , Issue.2 , pp. 505-516
    • Möhler, H.1
  • 43
    • 84856094645 scopus 로고    scopus 로고
    • Limbic responses to reward cues correlate with antisocial trait density in heavy drinkers
    • Oberlin B.G., Dzemidzic M., Bragulat V., Lehigh C.A., Talavage T., O'Connor S.J., et al. Limbic responses to reward cues correlate with antisocial trait density in heavy drinkers. Neuroimage 2012, 60(1):644-652.
    • (2012) Neuroimage , vol.60 , Issue.1 , pp. 644-652
    • Oberlin, B.G.1    Dzemidzic, M.2    Bragulat, V.3    Lehigh, C.A.4    Talavage, T.5    O'Connor, S.J.6
  • 46
    • 37749005257 scopus 로고    scopus 로고
    • Correlation between the SERT binding densities in hypothalamus and amygdala in Cloninger type 1 and 2 alcoholics
    • Storvik M., Haukijärvi T., Tupala E., Tiihonen J. Correlation between the SERT binding densities in hypothalamus and amygdala in Cloninger type 1 and 2 alcoholics. Alcohol and Alcoholism 2008, 43(1):25-30.
    • (2008) Alcohol and Alcoholism , vol.43 , Issue.1 , pp. 25-30
    • Storvik, M.1    Haukijärvi, T.2    Tupala, E.3    Tiihonen, J.4
  • 47
    • 85042599958 scopus 로고    scopus 로고
    • 5-HT(1A) receptors in the frontal cortical brain areas in Cloninger type 1 and 2 alcoholics measured by whole-hemisphere autoradiography
    • Storvik M., Häkkinen M., Tupala E., Tiihonen J. 5-HT(1A) receptors in the frontal cortical brain areas in Cloninger type 1 and 2 alcoholics measured by whole-hemisphere autoradiography. Alcohol and Alcoholism 2009, 44(1):2-7.
    • (2009) Alcohol and Alcoholism , vol.44 , Issue.1 , pp. 2-7
    • Storvik, M.1    Häkkinen, M.2    Tupala, E.3    Tiihonen, J.4
  • 48
    • 34047105847 scopus 로고    scopus 로고
    • Nucleus accumbens serotonin transporters in alcoholics measured by whole-hemisphere autoradiography
    • Storvik M., Tiihonen J., Haukijärvi T., Tupala E. Nucleus accumbens serotonin transporters in alcoholics measured by whole-hemisphere autoradiography. Alcohol 2006, 40(3):177-184.
    • (2006) Alcohol , vol.40 , Issue.3 , pp. 177-184
    • Storvik, M.1    Tiihonen, J.2    Haukijärvi, T.3    Tupala, E.4
  • 49
    • 0027429280 scopus 로고
    • No age-related changes in human benzodiazepine receptor binding measured by PET with 11C Ro 15-4513
    • Suhara T., Inoue O., Kobayashi K., Suzuki K., Itoh T., Tateno Y. No age-related changes in human benzodiazepine receptor binding measured by PET with 11C Ro 15-4513. Neuroscience Letters 1993, 159(1-2):207-210.
    • (1993) Neuroscience Letters , vol.159 , Issue.1-2 , pp. 207-210
    • Suhara, T.1    Inoue, O.2    Kobayashi, K.3    Suzuki, K.4    Itoh, T.5    Tateno, Y.6
  • 50
    • 0036704933 scopus 로고    scopus 로고
    • Frontal-subcortical neuronal circuits and clinical neuropsychiatry: an update
    • Tekin S., Cummings J.L. Frontal-subcortical neuronal circuits and clinical neuropsychiatry: an update. Journal of Psychosomatic Research 2002, 53(2):647-654.
    • (2002) Journal of Psychosomatic Research , vol.53 , Issue.2 , pp. 647-654
    • Tekin, S.1    Cummings, J.L.2
  • 51
  • 53
    • 0035059958 scopus 로고    scopus 로고
    • Dopamine D(2)/D(3)-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics
    • Tupala E., Hall H., Bergström K., Särkioja T., Räsänen P., Mantere T., et al. Dopamine D(2)/D(3)-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics. Molecular Psychiatry 2001, 6(3):261-267.
    • (2001) Molecular Psychiatry , vol.6 , Issue.3 , pp. 261-267
    • Tupala, E.1    Hall, H.2    Bergström, K.3    Särkioja, T.4    Räsänen, P.5    Mantere, T.6
  • 54
    • 0034728072 scopus 로고    scopus 로고
    • Dopamine-transporter density in nucleus accumbens of type-1 alcoholics
    • Tupala E., Hall H., Särkioja T., Räsänen P., Tiihonen J. Dopamine-transporter density in nucleus accumbens of type-1 alcoholics. Lancet 2000, 355(9201):380.
    • (2000) Lancet , vol.355 , Issue.9201 , pp. 380
    • Tupala, E.1    Hall, H.2    Särkioja, T.3    Räsänen, P.4    Tiihonen, J.5
  • 56
    • 0028053207 scopus 로고
    • CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers
    • Virkkunen M., Rawlings R., Tokola R., Poland R.E., Guidotti A., Nemeroff C., et al. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry 1994, 51(1):20-27.
    • (1994) Archives of General Psychiatry , vol.51 , Issue.1 , pp. 20-27
    • Virkkunen, M.1    Rawlings, R.2    Tokola, R.3    Poland, R.E.4    Guidotti, A.5    Nemeroff, C.6
  • 57
    • 0023891829 scopus 로고
    • Benzodiazepine receptor sites in the human brain: autoradiographic mapping
    • Zezula J., Cortés R., Probst A., Palacios J.M. Benzodiazepine receptor sites in the human brain: autoradiographic mapping. Neuroscience 1988, 25(3):771-795.
    • (1988) Neuroscience , vol.25 , Issue.3 , pp. 771-795
    • Zezula, J.1    Cortés, R.2    Probst, A.3    Palacios, J.M.4


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