Novel formulation strategies for enhancing oral delivery of methoxyflavones in Kaempferia parviflora by SMEDDS or complexation with 2-hydroxypropyl-β- cyclodextrin

International Journal of Pharmaceutics

Volumn 445, Issue 1-2, 2013, Pages 1-11

  Mekjaruskul, Catheleeya ^a   Yang, Yu Tsai ^b   Leed, Marina G D ^b   Sadgrove, Matthew P ^b   Jay, Michael ^b   Sripanidkulchai, Bungorn ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

^b University of North Carolina   (United States)

Author keywords

2 Hydroxypropyl cyclodextrin; Bioavailability; Kaempferia parviflora; Methoxyflavones; Self microemulsifying drug delivery system

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 3,5,7,3',4' PENTAMETHOXYFLAVONE; 5,7 DIMETHOXYFLAVONE; 5,7,4' TRIMETHOXYFLAVONE; ALCOHOL; APHRODISIAC AGENT; COCONUT OIL; FLAVONE DERIVATIVE; HYDROCHLORIC ACID; MACROGOL; MACROGOL 400; PHOSPHATE BUFFERED SALINE; PROPYLENE GLYCOL; RICINOMACROGOL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; FREEZE DRYING; HUMAN; IN VITRO STUDY; IN VIVO CULTURE; KAEMPFERIA PARVIFLORA; MALE; NONHUMAN; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM; ZINGIBERACEAE;

ADMINISTRATION, ORAL; ANIMALS; BETA-CYCLODEXTRINS; CACO-2 CELLS; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FLAVONOIDS; HUMANS; MALE; PERMEABILITY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RHIZOME; SOLUBILITY; ZINGIBERACEAE;

EID: 84874007720     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.01.052     Document Type: Article

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