The efficacy of saline washout technique in the management of exfoliant and vesicant chemotherapy extravasation: A historical case series report

European Journal of Cancer Care

Volumn 22, Issue 2, 2013, Pages 169-178

  Harrold, K ^a   Gould, D ^b   Drey, N ^b  

^a MOUNT VERNON CANCER CENTRE   (United Kingdom)

^b CITY UNIVERSITY   (United Kingdom)

Author keywords

Exfoliant chemotherapy; Extravasation; Saline washout technique; Vesicant chemotherapy

Indexed keywords

ANTIDOTE; ANTINEOPLASTIC AGENT; SODIUM CHLORIDE;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTRAST MEDIUM EXTRAVASATION; FEMALE; HUMAN; LAVAGE; MALE; MIDDLE AGED; NEOPLASM; OUTCOME ASSESSMENT;

ADOLESCENT; ADULT; AGED; ANTIDOTES; ANTINEOPLASTIC AGENTS; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; OUTCOME ASSESSMENT (HEALTH CARE); SODIUM CHLORIDE; THERAPEUTIC IRRIGATION; YOUNG ADULT;

EID: 84873999219     PISSN: 09615423     EISSN: 13652354     Source Type: Journal    
DOI: 10.1111/ecc.12023     Document Type: Article

References (29)

1. Albanell J. & Baselga J. (2000) Systemic therapy emergencies. Seminars in Oncology 27, 347-361.
2. Allwood M., Stanley A. & Wright P., eds (2002) The Cytotoxic Handbook, 4th edn. Radcliffe Medical Press, Oxford, UK.
3. Arroyo P.A., Perez R.U., Feijoo M.A. & Hernandez M.A. (2010) Good clinical and cost outcomes using dexrazoxane to treat accidental epirubicin extravasation. Journal of Cancer Research and Therapeutics 6, 573-574. Available at: http://www.cancerjournal.net/text.asp?2010/6/4/573/77081
4. Cancer Research UK (2011) Info.cancerresearchuk.org/CancerStats (Online). Available at: http://publications.cancerresearchuk.org/downloads/product/CS_REPORT_TOP20INCMORT.pdf (last accessed 16 March 2012).
5. Cole T. (2006) Risks and benefits of needle use in patients after axillary node surgery. British Journal of Nursing 15, 969-974.
6. Department of Health (DOH) (2009) Chemotherapy Services in England: Ensuring Quality and Safety. A report from the National Chemotherapy Advisory Group. Gateway reference No.: 12208. Available at: http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/documents/digitalasset/dh_104501.pdf (last accessed 16 March 2012).
7. Department of Health (DOH) (2010a) The NHS QIPP Challenge: An Introduction for Clinicians. Available at: http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_113806 (last accessed 24 June 2011).
8. Department of Health (DOH) (2010b) The NHS White Paper - Equity and Excellence: Liberating the NHS. Available at: http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/dh/en/ps/documents/digitalas_117352.pdf (last accessed 24 June 2011).
9. Department of Health (DOH) (2011a) National Cancer Peer Review - National Cancer Action Team (NCAT). Chemotherapy Measures v1.0 (2011). Manual for Cancer Services. Gateway reference No.: 16104. Available at: http://www.dh.gov.uk/en/Consultations/Responsestoconsultations/DH_127744 (last accessed 16 March 2012).
10. Department of Health (DOH) (2011b) Improving Outcomes: A Strategy for Cancer. Gateway reference no:15108. Available at: http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_123371 (last accessed 6 May 2011).
11. Dougherty L. (2010) Extravasation: prevention, recognition and management. Nursing Standard 24, 48-55.
12. Dougherty L. & Lister S., eds (2008) Drug administration: cytotoxic drugs. In: The Royal Marsden Hospital Manual of Clinical Nursing Procedures, 7th edn (eds Dougherty L. & Lister S. ), pp. 255-288. Wiley-Blackwell Publishing, Chichester, UK.
13. Dougherty L. & Oakley C. (2011) Advanced practice in the management of extravasation. Cancer Nursing Practice 10, 16-22.
14. Electronic Medical Compendium (eMC) (2012). Available at: http://www.medicines.org.uk/emc (last accessed 1 April 2012).
15. Ener R., Meglathery S. & Styler M. (2004) Extravasation of systemic haemato-oncological therapies. Annals of Oncology 15, 858-862.
16. European Oncology Nursing Society (EONS) (2007) Extravasation Guidelines Implementation Toolkit. http://www.cancernurse.eu/documents/EONSClinicalGuidelinesSection6-en.pdf (last accessed 22 April 2011).
17. Fontaine C., Noens L., Pierre P. & DeGreve J. (2012) Savene (dexrazoxane) use in clinical practice. Supportive Care in Cancer. Short communication. Published on line Springer-Verlag. doi: 10.1007/s00520-012-1382-2 27/01/2012
18. Gault D.T. (1993) Extravasation injuries. British Journal of Plastic Surgery 46, 91-96.
19. Mourisden H.T., Langer S.W., Butler J., Eidtmann H., Rosti G., De Wit M., Knoblauch P., Rasmussen A., Dahlstrom K., Jensen P.B. & Giaccone G. (2007) Treatment of anthracycline extravasation with Savene® (Dexrazoxane): results from two prospective clinical multicentre studies. Annals of Oncology 18, 546-550.
20. Olsen A.L. & Mc Ginness J.M. (2010) Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice Based Approaches: Workshop Summary. IOM (Institute of Medicine). The National Academies Press, Washington DC, USA.
21. RCN (2010) Standards of Infusion Therapy. RCN IV Therapy Forum, 3rd edn. RCN Publishers, London, UK.
22. Roe H. (2011) Anthracycline extravasations: prevention and management. British Journal of Nursing 20 (Oncology supplement), 16-22.
23. Schrijvers D.L. (2003) Extravasation: a dreaded complication of chemotherapy. Annals of Oncology 14 (Suppl. 3), piii26-iiii30.
24. Schulmeister L. (2008) Managing vesicant extravasations. The Oncologist 13, 284-288.
25. Schulmeister L. (2011) Extravasation management: clinical update. Seminars in Oncology Nursing 27, 82-90.
26. Steiert A., Hille U., Burke W., Gohritz A., Zilz S., Herold C. & Vogt P.M. (2011) Subcutaneous wash-out procedure (SWOP) for the treatment of chemotherapeutic extravasations. Journal of Plastic, Reconstructive and Aesthetic Surgery 64, 240-247.
27. Thakur J.S., Chauhan C.G.S., Diwana V.K., Chauhan D.C. & Thakur A. (2008) Extravasational side effects of cytotoxic drugs; a preventable catastrophe. Indian Journal of Plastic Surgery 41, 145-150.
28. Tyson A.M. & Gay W.E. (2010) Successful experience utilizing dexrazoxane treatment for an anthracycline extravasation. The Annals of Pharmacotherapy 44, 922-925.
29. United Kingdom Oncology Nursing Society (UKONS) (2008) Anthracycline Extravasation Management Guidelines. Available at: http://www.ukons.org