Attenuation of androgenic regulation by brefeldin A in androgen-responsive prostate cancer cells

Urologic Oncology: Seminars and Original Investigations

Volumn 31, Issue 1, 2013, Pages 104-109

  Alexander, Bobby ^a   Fishman, Andrew I ^a   Green, David ^a   Choudhury, Muhammad S ^a   Konno, Sensuke ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Androgen receptor; Brefeldin A; Prostate cancer; Prostate specific antigen

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; BREFELDIN A; PROSTATE SPECIFIC ANTIGEN; TRYPAN BLUE;

ARTICLE; BINDING ASSAY; CELL GROWTH; CELL STRAIN LNCAP; CONTROLLED STUDY; DRUG ACTIVITY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER; SYNTHESIS;

ANDROGENS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREFELDIN A; CELL PROLIFERATION; DIHYDROTESTOSTERONE; HUMANS; MALE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; PROTEIN SYNTHESIS INHIBITORS; RECEPTORS, ANDROGEN; TUMOR CELLS, CULTURED;

EID: 84873998604     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2010.11.009     Document Type: Article

References (23)

1. Denis L. Prostate cancer: Primary hormonal treatment. Cancer 1993, 71:1050-1058.
2. McLeod D.G. Antiandrogenic drugs. Cancer 1993, 71:1046-1049.
3. Bilhartz D.L., Tindall D.J., Oesterling J.E. Prostate-specific antigen and prostatic acid phosphatase: Biomolecular and physiologic characteristics. Urology 1991, 38:95-102.
4. Stamey T.A., Yang N., Hay A.R., et al. Prostate specific antigen as a serum marker for adenocarcinoma of the prostate. N Engl J Med 1987, 317:909-916.
5. Catalona W.J., Smith D.S., Ratliff T.L., et al. Measurement of prostate-specific antigen in serum as a screening test for prostate cancer. N Engl J Med 1991, 324:1156-1161.
6. Gittes R.F. Carcinoma of the prostate. N Engl J Med 1991, 324:236-245.
7. Horoszewicz J.S., Leong S.S., Kawinski E., et al. LNCaP model of human prostatic carcinoma. Cancer Res 1983, 43:1809-1818.
8. Tamura G., Ando K., Suzuki S., et al. Antiviral activity of brefeldin A and verrucarin A. J Antibiot 1968, 21:160-161.
9. Misumi Y., Miki A., Takatsuki A., et al. Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J Biol Chem 1986, 261:11398-11403.
10. Fujiwara T., Oda K., Yokota S., et al. Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J Biol Chem 1988, 263:18545-18552.
11. Lippincott-Schwartz J., Yuan L.C., Bonifacino J.S., et al. Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER. Cell 1989, 56:801-813.
12. Trapman J., Ris-Stalpers C., Van der Korput J.A.G.M., et al. The androgen receptor: Functional structure and expression in transplanted human prostate tumors and prostate tumor cell lines. J Steroid Biochem Mol Biol 1990, 37:837-842.
13. Liu S., Yamauchi H. Hinokitiol, a metal chelator derived from natural plants, suppresses cell growth and disrupts androgen receptor signaling in prostate carcinoma cell lines. Biochem Biophys Res Commun 2006, 351:26-32.
14. Gau J.T., Salter R.D., Krill D., et al. Biosynthesis and secretion of prostate-specific antigen in LNCaP cells. Cancer Res 1997, 57:3830-3834.
15. Singh P., Hallur G., Anchoori R.K., et al. Rational design of novel antiandrogens for neutralizing androgen receptor function in hormone refractory prostate cancer. Prostate 2008, 68:1570-1581.
16. Culig Z., Hobisch A., Cronauer M.V., et al. Regulation of prostatic growth and function by peptide growth factors. Prostate 1996, 28:392-405.
17. Denis L.J., Griffiths K. Endocrine treatment in prostate cancer. Semin Surg Oncol 2000, 18:52-74.
18. Mollenhauer H.H., Morre D.J., Rowe L.D. Alteration of intracellular traffic by monensin; mechanism, specificity, and relationship to toxicity. Biochim Biophys Acta 1990, 1031:225-246.
19. Pow D.V., Morris J.F. Tunicamycin, puromycin, and brefeldin A influence the subcellular distribution of neuropeptides in hypothalamic magnocellular neurons of rat. Cell Tissue Res 1992, 269:547-560.
20. 2 phase of cell cycle in a p53-dependent manner. J Biol Chem 2005, 280:20059-20068.
21. Hastak K., Gupta S., Ahmad N., et al. Role of p53 and NF-κB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene 2003, 22:4851-4859.
22. Wallen E., Sellers R.G., Peehl D.M. Brefeldin A induces p53-independent apoptosis in primary cultures of human prostate cancer cells. J Urol 2000, 164:836-841.
23. Duksin D., Mahoney W.C. Relationship of the structure and biological activity of the natural homologues of tunicamycin. J Biol Chem 1982, 257:3105-3109.