Prospective, multicenter study of ventricular assist device infections

Circulation

Volumn 127, Issue 6, 2013, Pages 691-702

  Gordon, Rachel J ^a,b   Weinberg, Alan D ^c   Pagani, Francis D ^f   Slaughter, Mark S ^g   Pappas, Pat S ^h   Naka, Yoshifumi ^a   Goldstein, Daniel J ⁱ   Dembitsky, Walter P ^j   Giacalone, Julie C ^a   Ferrante, Jennifer ^c   Ascheim, Deborah D ^c,d   Moskowitz, Alan J ^c   Rose, Eric A ^c   Gelijns, Annetine C ^e   Lowy, Franklin D ^a  

^a Columbia University College of Physicians ^*  (United States)

^b Department of Medicine   (United States)

^c International Center for Health Outcomes and Innovation Research   (United States)

^d Zena and Michael A Wiener Cardiovascular Institute   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^g University of Louisville School of Medicine   (United States)

^h ADVOCATE CHRIST MEDICAL CENTER   (United States)

ⁱ MONTEFIORE MEDICAL CENTER   (United States)

^j SHARP MEMORIAL HOSPITAL   (United States)

more..

Author keywords

Depression; Heart failure; Heart assist devices; Infection; Kidney

Indexed keywords

ALBUMIN; ANTIBIOTIC AGENT; BILIRUBIN; CREATININE; FRESH FROZEN PLASMA;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; CACHEXIA; CANDIDIASIS; CAUSE OF DEATH; CLINICAL STUDY; CLOSTRIDIUM DIFFICILE INFECTION; COAGULASE NEGATIVE STAPHYLOCOCCUS; COMORBIDITY; CONVALESCENCE; CORONARY ARTERY BYPASS SURGERY; CREATININE BLOOD LEVEL; DEPRESSION; DEVICE INFECTION; DIABETES MELLITUS; DISEASE DURATION; DISEASE SEVERITY; ENTEROCOCCUS FAECALIS; FEMALE; HEART ATRIUM FIBRILLATION; HEART INFARCTION; HEART VENTRICLE ARRHYTHMIA; HUMAN; INCIDENCE; INFECTION RISK; KIDNEY DYSFUNCTION; KIDNEY FAILURE; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; MORTALITY; NUTRITIONAL STATUS; OBESITY; PERCUTANEOUS CORONARY INTERVENTION; PEROPERATIVE CARE; PNEUMONIA; POSTOPERATIVE CARE; PREOPERATIVE CARE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSEUDOMONAS INFECTION; RESPIRATORY FAILURE; RISK FACTOR; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS INFECTION; TREATMENT OUTCOME; URINARY TRACT INFECTION; VENTRICULAR ASSIST DEVICE; WOUND INFECTION;

ADULT; AGED; CARDIOVASCULAR INFECTIONS; CREATININE; DEPRESSION; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HEART FAILURE; HEART-ASSIST DEVICES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROSTHESIS-RELATED INFECTIONS; PSEUDOMONAS INFECTIONS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STAPHYLOCOCCAL INFECTIONS; TREATMENT OUTCOME;

EID: 84873985667     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.128132     Document Type: Article

References (43)

1. Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, Poirier VL, Dasse KA; HeartMate LVAS Investigators, Left Ventricular Assist System. Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122:1186-1195.
2. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Long JW, Ascheim DD, Tierney AR, Levitan RG, Watson JT, Meier P, Ronan NS, Shapiro PA, Lazar RM, Miller LW, Gupta L, Frazier OH, Desvigne-Nickens P, Oz MC, Poirier VL; Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345: 1435-1443.
3. Kirklin JK, Naftel DC, Kormos RL, Stevenson LW, Pagani FD, Miller MA, Ulisney KL, Baldwin JT, Young JB. Second INTERMACS annual report: more than 1, 000 primary left ventricular assist device implants. J Heart Lung Transplant. 2010;29:1-10.
4. Holman WL, Park SJ, Long JW, Weinberg A, Gupta L, Tierney AR, Adamson RM, Watson JD, Raines EP, Couper GS, Pagani FD, Burton NA, Miller LW, Naka Y; REMATCH Investigators. Infection in permanent circulatory support: experience from the REMATCH trial. J Heart Lung Transplant. 2004;23:1359-1365.
5. Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD, Conte JV, Naka Y, Mancini D, Delgado RM, MacGillivray TE, Farrar DJ, Frazier OH; HeartMate II Clinical Investigators. Use of a continuous- flow device in patients awaiting heart transplantation. N Engl J Med. 2007;357:885-896.
6. Gordon RJ, Quagliarello B, Lowy FD. Ventricular assist device-related infections. Lancet Infect Dis. 2006;6:426-437.
7. Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, Sun B, Tatooles AJ, Delgado RM 3rd, Long JW, Wozniak TC, Ghumman W, Farrar DJ, Frazier OH; HeartMate II Investigators. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009;361:2241-2251.
8. Hannan MM, Husain S, Mattner F, Danziger-Isakov L, Drew RJ, Corey GR, Schueler S, Holman WL, Lawler LP, Gordon SM, Mahon NG, Herre JM, Gould K, Montoya JG, Padera RF, Kormos RL, Conte JV, Mooney ML; International Society for Heart and Lung Transplantation. Working formulation for the standardization of definitions of infections in patients using ventricular assist devices. J Heart Lung Transplant. 2011;30:375-384.
9. UAB School of Medicine. Interagency Registry for Mechanical Circulatory Support. www.uab.edu/intermacs. Accessed April 13, 2012.
10. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
11. Cox DR. Regression models and life tables (with discussion). J R Stat Soc. 1972;34:187-220.
12. Blackstone EH, Naftel DC, Turner ME Jr. The decomposition of timevarying hazard into phases, each incorporating a separate stream of concomitant information. J Am Stat Assoc. 1986;81:615-624.
13. Allison PD. Survival analysis using SAS: a practical guide. Cary, NC: SAS Institute Inc; 2010.
14. Simon D, Fischer S, Grossman A, Downer C, Hota B, Heroux A, Trenholme G. Left ventricular assist device-related infection: treatment and outcome. Clin Infect Dis. 2005;40:1108-1115.
15. Sivaratnam K, Duggan JM. Left ventricular assist device infections: three case reports and a review of the literature. ASAIO J. 2002;48:2-7.
16. Zierer A, Melby SJ, Voeller RK, Guthrie TJ, Ewald GA, Shelton K, Pasque MK, Moon MR, Damiano RJ Jr, Moazami N. Late-onset driveline infections: the Achilles' heel of prolonged left ventricular assist device support. Ann Thorac Surg. 2007;84:515-520.
17. Deng MC, Loebe M, El-Banayosy A, Gronda E, Jansen PG, Vigano M, Wieselthaler GM, Reichart B, Vitali E, Pavie A, Mesana T, Loisance DY, Wheeldon DR, Portner PM. Mechanical circulatory support for advanced heart failure: effect of patient selection on outcome. Circulation. 2001;103:231-237.
18. Monkowski DH, Axelrod P, Fekete T, Hollander T, Furukawa S, Samuel R. Infections associated with ventricular assist devices: epidemiology and effect on prognosis after transplantation. Transpl Infect Dis. 2007;9:114-120.
19. Sinha P, Chen JM, Flannery M, Scully BE, Oz MC, Edwards NM. Infections during left ventricular assist device support do not affect posttransplant outcomes. Circulation. 2000;102(suppl 3):III194-III199.
20. Kalya AV, Tector AJ, Crouch JD, Downey FX, McDonald ML, Anderson AJ, Bartoszewski CJ, Hosenpud JD. Comparison of Novacor and Heart- Mate vented electric left ventricular assist devices in a single institution. J Heart Lung Transplant. 2005;24:1973-1975.
21. Toba FA, Akashi H, Arrecubieta C, Lowy FD. Role of biofilm in Staphylococcus aureus and Staphylococcus epidermidis ventricular assist device driveline infections. J Thorac Cardiovasc Surg. 2011;141:1259-1264.
22. Arrecubieta C, Toba FA, von Bayern M, Akashi H, Deng MC, Naka Y, Lowy FD. SdrF, a Staphylococcus epidermidis surface protein, contributes to the initiation of ventricular assist device driveline-related infections. PLoS Pathog. 2009;5:e1000411.
23. Arrecubieta C, Asai T, Bayern M, Loughman A, Fitzgerald JR, Shelton CE, Baron HM, Dang NC, Deng MC, Naka Y, Foster TJ, Lowy FD. The role of Staphylococcus aureus adhesins in the pathogenesis of ventricular assist device-related infections. J Infect Dis. 2006;193:1109-1119.
24. Gordon SM, Schmitt SK, Jacobs M, Smedira NM, Goormastic M, Banbury MK, Yeager M, Serkey J, Hoercher K, McCarthy PM. Nosocomial bloodstream infections in patients with implantable left ventricular assist devices. Ann Thorac Surg. 2001;72:725-730.
25. Hauser AB, Stinghen AE, Kato S, Bucharles S, Aita C, Yuzawa Y, Pecoits- Filho R. Characteristics and causes of immune dysfunction related to uremia and dialysis. Perit Dial Int. 2008;28(suppl 3):S183-S187.
26. Malani PN, Dyke DB, Pagani FD, Chenoweth CE. Nosocomial infections in left ventricular assist device recipients. Clin Infect Dis. 2002;34:1295-1300.
27. Konstam V, Moser DK, De Jong MJ. Depression and anxiety in heart failure. J Card Fail. 2005;11:455-463.
28. Adams J, Kuchibhatla M, Christopher EJ, Alexander JD, Clary GL, Cuffe MS, Califf RM, Krishnan RR, O'Connor CM, Jiang W. Association of depression and survival in patients with chronic heart failure over 12 years. Psychosomatics. 2012;53:339-346.
29. Frasure-Smith N, Lespérance F, Habra M, Talajic M, Khairy P, Dorian P, Roy D; Atrial Fibrillation and Congestive Heart Failure Investigators. Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure. Circulation. 2009;120:134-140, 3p following 140.
30. Diez-Quevedo C, Lupon J, Gonzalez B, Urrutia A, Cano L, Cabanes R, Altimir S, Coll R, Pascual T, de Antonio M, Bayes-Genis A. Depression, antidepressants, and long-term mortality in heart failure [published online ahead of print April 14, 2012]. Int J Cardiol. doi:10.1016/j. ijcard.2012.03.143.
31. Rutledge T, Reis VA, Linke SE, Greenberg BH, Mills PJ. Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol. 2006;48:1527-1537.
32. Pelle AJ, Gidron YY, Szabó BM, Denollet J. Psychological predictors of prognosis in chronic heart failure. J Card Fail. 2008;14:341-350.
33. Jiang W, Kuchibhatla M, Clary GL, Cuffe MS, Christopher EJ, Alexander JD, Califf RM, Krishnan RR, O'Connor CM. Relationship between depressive symptoms and long-term mortality in patients with heart failure. Am Heart J. 2007;154:102-108.
34. Doering LV, Martínez-Maza O, Vredevoe DL, Cowan MJ. Relation of depression, natural killer cell function, and infections after coronary artery bypass in women. Eur J Cardiovasc Nurs. 2008;7:52-58.
35. Tully PJ, Pedersen SS, Winefield HR, Baker RA, Turnbull DA, Denollet J. Cardiac morbidity risk and depression and anxiety: a disorder, symptom and trait analysis among cardiac surgery patients. Psychol Health Med. 2011;16:333-345.
36. Owen JE, Bonds CL, Wellisch DK. Psychiatric evaluations of heart transplant candidates: predicting post-transplant hospitalizations, rejection episodes, and survival. Psychosomatics. 2006;47:213-222.
37. Doering LV, Cross R, Vredevoe D, Martinez-Maza O, Cowan MJ. Infection, depression, and immunity in women after coronary artery bypass: a pilot study of cognitive behavioral therapy. Altern Ther Health Med. 2007;13:18-21.
38. Casida JM, Parker J. A preliminary investigation of symptom pattern and prevalence before and up to 6 months after implantation of a left ventricular assist device. J Artif Organs. 2012;15:211-214.
39. Eshelman AK, Mason S, Nemeh H, Williams C. LVAD destination therapy: applying what we know about psychiatric evaluation and management from cardiac failure and transplant. Heart Fail Rev. 2009;14:21-28.
40. Baba A, Hirata G, Yokoyama F, Kenmoku K, Tsuchiya M, Kyo S, Toyoshima R. Psychiatric problems of heart transplant candidates with left ventricular assist devices. J Artif Organs. 2006;9:203-208.
41. Tigges-Limmer K, Schönbrodt M, Roefe D, Arusoglu L, Morshuis M, Gummert JF. Suicide after ventricular assist device implantation. J Heart Lung Transplant. 2010;29:692-694.
42. Minami K, El-Banayosy A, Sezai A, Arusoglu L, Sarnowsky P, Fey O, Koerfer R. Morbidity and outcome after mechanical ventricular support using Thoratec, Novacor, and HeartMate for bridging to heart transplantation. Artif Organs. 2000;24:421-426.
43. UAB School of Medicine. http://www.uab.edu/intermacs/images/Federal- Quarterly-Report/INTERMACS-Quarterly-Statistical-Report-2012-Q2-2.pdf. Accessed October 16, 2012.