Efficacy of dextromethorphan and cyclosporine a for acute encephalopathy

Pediatric Neurology

Volumn 48, Issue 3, 2013, Pages 200-205

  Matsuo, Muneaki ^a   Maeda, Toshiyuki ^a   Ono, Nobuyasu ^a,b   Sugihara, Susumu ^c   Kobayashi, Ikuko ^a   Koga, Daisuke ^a   Hamasaki, Yuhei ^a  

^a SAGA UNIVERSITY   (Japan)

^b Ureshino Medical Center   (Japan)

^c Gunma Children's Medical Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; CYCLOSPORIN A; DEXTROMETHORPHAN; DIAZEPAM; MIDAZOLAM; PHENOBARBITAL; VALPROIC ACID;

ACUTE BRAIN DISEASE; ACUTE ENCEPHALOPATHY WITH BIPHASIC SEIZURES AND LATE REDUCED DIFFUSION; ARTICLE; CHILD; CLINICAL ARTICLE; CONSCIOUSNESS DISORDER; CONTINUOUS INFUSION; DISEASE ASSOCIATION; DRUG EFFICACY; EXANTHEMA SUBITUM; FEBRILE CONVULSION; FEMALE; FEVER; FOCAL EPILEPSY; HUMAN; HYPERACTIVITY; INFANT; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; TONIC CLONIC SEIZURE;

CYCLOSPORINE; DEXTROMETHORPHAN; DRUG THERAPY, COMBINATION; ENCEPHALITIS; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HUMANS; INFANT; MALE; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; TREATMENT OUTCOME;

EID: 84873977083     PISSN: 08878994     EISSN: 18735150     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2012.11.003     Document Type: Article

References (19)

1. J. Takanashi, H. Oba, and A.J. Barkovich Diffusion MRI abnormalities after prolonged febrile seizures with encephalopathy Neurology 66 2006 1304 1309
2. J. Takanashi, M. Tsuji, K. Amemiya, H. Tada, and A.J. Barkovich Mild influenza encephalopathy with biphasic seizures and late reduced diffusion J Neurol Sci 256 2007 86 89
3. M. Mizuguchi, H. Yamanouchi, T. Ichiyama, and M. Shiomi Acute encephalopathy associated with influenza and other viral infections Acta Neurol Scand Suppl 186 2007 45 56
4. H. Yamanouchi, N. Kawaguchi, and M. Mori Acute infantile encephalopathy predominantly affecting the frontal lobes Pediatr Neurol 34 2006 93 100
5. J. Takanashi, H. Tada, H. Terada, and A.J. Barkovich Excitotoxicity in acute encephalopathy with biphasic seizures and late reduced diffusion AJNR Am J Neuroradiol 30 2009 132 135
6. M.P. Mattson Excitotoxic and excitoprotective mechanisms: Abundant targets for the prevention and treatment of neurodegenerative disorders NeuroMolecular Med 3 2003 65 94
7. T. Ichiyama, N. Suenaga, and M. Kajimoto Serum and CSF levels of cytokines in acute encephalopathy following prolonged febrile seizures Brain Dev 30 2008 47 52
8. Y. Sakamoto Diagnostics for pediatric neurology 1978 Kanehara Co. LTD (in Japanese)
9. M. Enjoji, N. Goya, and T. Kurokawa Enjoji Scale of Analytical Development for Infant and Toddler 1977 Keio University Press (in Japanese)
10. A. Hoshino, M. Saitoh, and A. Oka Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndromes Brain Dev 34 2012 337 343
11. M.M. Osman, D. Lulic, and L. Glover Cyclosporine-A as a neuroprotective agent against stroke: Its translation from laboratory research to clinical application Neuropeptides 45 2011 359 368
12. H. Friberg, and T. Wieloch Mitochondrial permeability transition in acute neurodegeneration Biochimie 84 2002 241 250
13. L. Khaspekov, H. Friberg, A. Halestrap, I. Viktorov, and T. Wieloch Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons Eur J Neurosci 11 1999 3194 3198
14. J. Hatton, B. Rosbolt, P. Empey, R. Kryscio, and B. Young Dosing and safety of cyclosporine in patients with severe brain injury: Clinical article J Neurosurg 109 2008 699 707
15. A.T. Mazzeo, G.M. Brophy, and C.B. Gilman Safety and tolerability of cyclosporin a in severe traumatic brain injury patients: Results from a prospective randomized trial J Neurotrauma 26 2009 2195 2206
16. A. Siu, and R. Drachtman Dextromethorphan: A review of N-methyl-D-aspartate receptor antagonist in the management of pain CNS Drug Rev 13 2007 96 106
17. R.A. Drachtman, P.D. Cole, and C.B. Golden Dextromethorphan is effective in the treatment of subacute methotrexate neurotoxicity Pediatr Hematol Oncol 19 2002 319 327
18. R. Alemzadeh, K. Gammeltoft, and K. Matteson Efficacy of low-dose dextromethorphan in the treatment of nonketotic hyperglycinemia Pediatrics 97 1996 924 926
19. Y. Maegaki, Y. Kurosawa, and A. Hayashi An early diagnosis of acute encephalopathy using early clinical, laboratory, and neuroimaging findings J Jpn Pediatr Soc 110 2006 1550 1557