Inhibition of peptidyl-arginine deiminases reverses protein- hypercitrullination and disease in mouse models of multiple sclerosis

DMM Disease Models and Mechanisms

Volumn 6, Issue 2, 2013, Pages 467-478

  Moscarello, Mario A ^a   Lei, Helena ^a   Mastronardi, Fabrizio G ^a   Winer, Shawn ^a   Tsui, Hubert ^a   Li, Zhen ^a   Ackerley, Cameron ^a   Zhang, Li ^a   Raijmakers, Reinout ^b,c   Wood, D Denise ^a  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLOROACETAMIDINE; ACETAMIDINE DERIVATIVE; CITRULLINE; EPITOPE; PROTEIN ARGININE DEIMINASE; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CELL INFILTRATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; HUMAN; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; SPINAL CORD; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; WHITE MATTER;

AMIDINES; ANIMALS; ANTIGENS, CD3; BRAIN; CITRULLINE; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME INHIBITORS; HUMANS; HYDROLASES; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MULTIPLE SCLEROSIS; OPTIC NERVE; SPLEEN; SURVIVAL ANALYSIS;

EID: 84873968855     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.010520     Document Type: Article

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