Allele-specific polymerase chain reaction for the detection of Alzheimer's disease-related single nucleotide polymorphisms

BMC Medical Genetics

Volumn 14, Issue 1, 2013, Pages

  Darawi, Mohd Nazif ^a   Ai Vyrn, Chin ^b   Ramasamy, Kalavathy ^a   Hua, Philip Poi Jun ^b   Pin, Tan Maw ^b   Kamaruzzaman, Shahrul Bahyah ^b   Majeed, Abu Bakar Abdul ^a  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Allele specific polymerase chain reaction; Alzheimer's disease; Apolipoprotein E; ATP binding cassette sub family A member 7; Bridging integrator; Clusterin; Complement receptor 1; Phosphatidylinositol binding clathrin assembly protein; Single nucleotide polymorphism

Indexed keywords

GENOMIC DNA;

ALZHEIMER DISEASE; AMPLICON; ARTICLE; COST EFFECTIVENESS ANALYSIS; DNA DETERMINATION; DNA SEQUENCE; GENE AMPLIFICATION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; OUTPATIENT CARE; POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; CLUSTERIN; FEMALE; GENETICS, POPULATION; GENOME, HUMAN; GENOTYPE; GENOTYPING TECHNIQUES; HUMANS; MALE; MONOMERIC CLATHRIN ASSEMBLY PROTEINS; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, COMPLEMENT 3B; REPRODUCIBILITY OF RESULTS; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SOFTWARE; TUMOR SUPPRESSOR PROTEINS;

EID: 84873941708     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-14-27     Document Type: Article

References (21)

1. Wimo A, Winblad B, Jönsson L. The worldwide societal costs of dementia: estimates for 2009. Alzheimers Dement 2010, 6:98-103. 10.1016/j.jalz.2010.01.010, 20298969.
2. Bekris LM, Yu CE, Bird TD, Tsuang DW. Genetics of Alzheimer's disease. J Geriat Psychiatry Neurol 2010, 23:213-227.
3. Borenstein AR, Copenhaver CI, Mortimer JA. Early-life risk factors for Alzheimer's disease. Alzheimer Dis Assoc Disord 2006, 20:63-72. 10.1097/01.wad.0000201854.62116.d7, 16493239.
4. Bertram L, Tanzi RE. Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nat Rev Neurosci 2008, 9:768-778. 10.1038/nrn2494, 18802446.
5. Mayeux R, Saunders AM, Shea S, Mirra S, Evans D, Hyman BT, Crain B, Tang MX, Phelps CH. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. N Engl J Med 1998, 338:506-511. 10.1056/NEJM199802193380804, 9468467.
6. Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE. Systematic meta-analyses of Alzheimer's disease genetic association studies: the AlzGene database. Nat Genet 2007, 39:17-23. 10.1038/ng1934, 17192785.
7. Kwok PY, Chen X. Detection of single nucleotide polymorphisms. Curr Issues Mol Biol 2003, 5:43-60.
8. Newton CR, Graham A, Hepstinstall LE, Powell SJ, Summers C, Kalsheker N, Smith JC, Markham AF. Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res 1989, 17:2503-2516. 10.1093/nar/17.7.2503, 317639, 2785681.
9. Myakishev MV, Khiripin Y, Hu S, Hamer HD. High-throughput SNP genotyping by allele-specific PCR with universal energy-transfer-labeled primers. Genome Res 2001, 11:163-169. 10.1101/gr.157901, 311033, 11156625.
10. Germer S, Higuchi R. Single-tube genotyping without oligonucleotide probes. Genome Res 1999, 9:72-78. 310703, 9927486.
11. Teh LK, Lee WL, Amir J, Salleh MZ, Ismail R. Single step PCR for detection of allelic variation of MDR1 gene (P-glycoprotein) among three ethnic groups in Malaysia. J J Clin Pharm Ther 2007, 32:313-319.
12. Chen Q, Lu P, Jones AV, Cross NC, Silver RT, Wang L. Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders. J Mol Diagn 2007, 9:272-276. 10.2353/jmoldx.2007.060133, 1867436, 17384221.
13. Mirasena S, Shimbhu D, Sanguansermsri M, Sanguansermsri T. Detection of beta-thalassemia mutations using a multiplex amplification refractory mutation system assay. Hemoglobin 2008, 32:403-409. 10.1080/03630260701798391, 18654891.
14. Sapkota BR, Ranjit C, Neupane KD, Macdonald M. Development and evaluation of a novel multipleprimer PCR amplification refractory mutation system for the rapid detection of mutations conferring rifampicin resistance in codon 425 of the rpoB gene of mycobacterium leprae. J Med Microbiol 2008, 57:179-184. 10.1099/jmm.0.47534-0, 18201983.
15. Wenham PR, Newton CR, Price WH. Analysis of apolipoprotein E genotypes by the amplification refractory mutation system. Clin Chem 1991, 37:241-244.
16. Donohoe GG, Salomaki A, Lehtimaki T, Pulkki K, Kairisto V. Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis. Clin Chem 1999, 45:143-146.
17. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990, 215:403-410.
18. Mammedov TG, Pienaar E, Whitney SE, TerMaat JR, Carvill G, Goliath R, Subramaniam A, Viljoen HJ. A fundamental study of the PCR amplification of GC-rich DNA templates. Comput Biol Chem 2008, 32:452-457. 10.1016/j.compbiolchem.2008.07.021, 2727727, 18760969.
19. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hhal. J Lipid Res 1990, 31:545-548.
20. Koch W, Ehrenhaft A, Griesser K, Pfeufer A, Müller J, Schömig A, Kastrati A. TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E. Clin Chem Lab Med 2002, 40:1123-1131.
21. Aydin A, Toliat MR, Bähring S, Becker C, Nürnberg P. New universal primers facilitate pyrosequencing. Electrophoresis 2006, 27:394-397. 10.1002/elps.200500467, 16331584.