Reamputation after Minor Foot Amputation in Diabetic Patients: Risk Factors Leading to Limb Loss

Journal of Foot and Ankle Surgery

Volumn 52, Issue 2, 2013, Pages 184-187

  Nerone, Vincent S ^a   Springer, Kevin D ^a   Woodruff, Darren M ^a   Atway, Said A ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Complication; Diabetes; Failure to heal; Foot ulcer; Neuropathy; Surgery; Vasculopathy

Indexed keywords

HEMOGLOBIN A1C;

ADULT; AGE; ARTERY BYPASS; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DIABETIC PATIENT; DIALYSIS; DISEASE SEVERITY; FEMALE; FOLLOW UP; FOOT AMPUTATION; GLYCEMIC CONTROL; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY PANCREAS TRANSPLANTATION; KIDNEY TRANSPLANTATION; LEG AMPUTATION; MAJOR CLINICAL STUDY; MAJOR SURGERY; MALE; MINOR SURGERY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; REOPERATION; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SMOKING;

AMPUTATION; DIABETIC FOOT; FEMALE; HUMANS; LOWER EXTREMITY; MALE; MIDDLE AGED; PERIPHERAL ARTERIAL DISEASE; REOPERATION; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TIME-TO-TREATMENT;

EID: 84873927915     PISSN: 10672516     EISSN: 15422224     Source Type: Journal    
DOI: 10.1053/j.jfas.2012.11.015     Document Type: Article

References (28)

1. Izumi Y., Satterfield K., Lee S., Harkless L.B. Risk of reamputation in diabetic patients stratified by limb and level of amputation: a 10-year observation. Diabetes Care 2006, 29:566-570.
2. Aulivola B., Hile C.N., Hamdan A.D., Sheahan M.G., Veraldi J.R., Skillman J.J., Campbell D.R., Scovell S.D., LoGerfo F.W., Pomposelli F.B. Major lower extremity amputation: outcome of a modern series. Arch Surg 2004, 139:395-399.
3. Snyder D.C., Salameh J.R., Clericuzio C.P. Retrospective review of forefoot amputations at a Veterans Affairs hospital and evaluation of post-amputation follow-up. Am J Surg 2006, 192:e51-e54.
4. Waters R.L., Perry J., Antonelli D., Hislop H. Energy cost of walking of amputees: the influence of level of amputation. J Bone Joint Surg Am 1976, 58:42-46.
5. Eckman M.H., Greenfield S., Mackey W.C., Wong J.B., Kaplan S., Sullivan L., Dukes K., Pauker S.G. Foot infections in diabetic patients: decision and cost-effectiveness analyses. JAMA 1995, 273:712-720.
6. Veterans Health Administration. Veterans Health Administration Preservation-Amputation Care and Treatment program directive (2012), 2012-020, August. Available at: Accessed December 24, 2012. http://www.va.gov/vhapublications/ViewPublication.asp?pub_ID=2778.
7. Selby J.V., Zhang D. Risk factors for lower extremity amputation in persons with diabetes. Diabetes Care 1995, 18:509-516.
8. Reiber G.E., Pecoraro R.E., Koepsell T.D. Risk factors for amputation in patients with diabetes mellitus: a case-control study. Ann Intern Med 1992, 117:97-105.
9. Reiber G.E., Vileikyte L., Boyko E.J., del Aguila M., Smith D.G., Lavery L.A., Boulton A.J. Causal pathways for incident lower-extremity ulcers in patients with diabetes from two settings. Diabetes Care 1999, 22:157-162.
10. Young B.A., Maynard C., Reiber G., Boyko E.J. Effects of ethnicity and nephropathy on lower-extremity amputation risk among diabetic veterans. Diabetes Care 2003, 26:495-501.
11. Lehto S., Ronnemaa T., Pyorala K., Laakso M. Risk factors predicting lower extremity amputations in patients with NIDDM. Diabetes Care 1996, 19:607-612.
12. Malay D.S., Margolis D.J., Hoffstad O.J., Bellamy S. The incidence and risks of failure to heal after lower extremity amputation for the treatment of diabetic neuropathic foot ulcer. J Foot Ankle Surg 2006, 45:366-374.
13. Boyko E.J., Ahroni J.H., Stensel V., Forsberg R.C., Davignon D.R., Smith D.G. A prospective study of risk factors for diabetic foot ulcer: the Seattle Diabetic Foot study. Diabetes Care 1999, 22:1036-1042.
14. Reichard P., Nilsson B.Y., Rosenqvist U. The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus. N Engl J Med 1993, 329:304-309.
15. Duckworth W., Abraira C., Moritz T., Reda D., Emanuele N., Reaven P.D., Zieve F.J., Marks J., Davis S.N., Hayward R., Warren S.R., Goldman S., McCarren M., Vitek M.E., Henderson W.G., Huang G.D. VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009, 360:129-139.
16. O'Connor DJ, Gargiulo NJ, Jang J. Hemoglobin A1c as a measure of disease severity and outcome in limb threatening ischemia. J Surg Res Epub 2011 Jul 23.
17. Nather A., Bee C.S., Huak C.Y., Chew J.L., Lin C.B., Neo S., Sim E.Y. Epidemiology of diabetic foot problems and predictive factors for limb loss. J Diabetes Complications 2008, 22:77-82.
18. Selvin E., Marinopoulos S., Berkenblit G., Rami T., Brancati F.L., Powe N.R., Golden S.H. Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus. Ann Intern Med 2004, 141:421-431.
19. Adler A.I., Boyko E.J., Ahroni J.H., Smith D.G. Lower-extremity amputation in diabetes: the independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers. Diabetes Care 1999, 22:1029-1035.
20. Younger A.S., Awwad M.A., Kalla T.P., de Vries G. Risk factors for failure of transmetatarsal amputation in diabetic patients: a cohort study. Foot Ankle Int 2009, 30:1177-1182.
21. Morbach S., Quante C., Ochs H.R., Gaschler F., Pallast J.M., Knevels U. Increased risk of lower-extremity amputation among Caucasian diabetic patients on dialysis. Diabetes Care 2001, 24:1689-1690.
22. McGrath N.M., Curran B.A. Recent commencement of dialysis is a risk factor for lower-extremity amputation in a high-risk diabetic population. Diabetes Care 2000, 23:432-433.
23. Ndip A., Rutter M.K., Vileikyte L., Vardhan A., Asari A., Jameel M., Tahir H.A., Lavery L.A., Boulton A.J. Dialysis treatment is an independent risk factor for foot ulceration in patients with diabetes and stage 4 or 5 chronic kidney disease. Diabetes Care 2010, 33:1811-1816.
24. Woeste G., Wullstein C., Pridohl O., Lübke P., Schwarz R., Kohlhaw K., Bechstein W.O. Incidence of minor and major amputations after pancreas/kidney transplantation. Transpl Int 2003, 16:128-132.
25. Knight R.J., Zela S., Schoenberg L., Podder H., Kerman R.H., Katz S., Van Buren C.T., Kahan B.D. The effect of pancreas transplantation on peripheral vascular disease complications. Transplant Proc 2004, 36:1069-1071.
26. Faglia E., Clerici G., Clerissi J., Gabrielli L., Losa S., Mantero M., Caminiti M., Curci V., Lupattelli T., Morabito A. Early and five-year amputation and survival rate of diabetic patients with critical limb ischemia: data of a cohort study of 564 patients. Eur J Vasc Endovasc Surg 2006, 32:484-490.
27. Dick F., Diehm N., Galimanis A., Husmann M., Schmidli J., Baumgartner I. Surgical or endovascular revascularization in patients with critical limb ischemia: influence of diabetes mellitus on clinical outcome. J Vasc Surg 2007, 45:751-761.
28. Hirsch A.T., Haskal Z.J., Hertzer N.R., Bakal C.W., Creager M.A., Halperin J.L., Hiratzka L.F., Murphy W.R.C., Olin J.W., Puschett J.B., Rosenfield K.A., Sacks D., Stanley J.C., Taylor L.M., White C.J., White J., White R.A., Antman E.M., Smith S.C., Adams C.D., Anderson J.L., Faxon D.P., Fuster V., Gibbons R.J., Halperin J.L., Hiratzka L.F., Hunt S.A., Jacobs A.K., Nishimura R., Ornato J.P., Page R.L., Riegel B. ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): executive summary-a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease) endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. J Am Coll Cardiol 2006, 47:1239-1312.