Distinctive Serum miRNA Profile in Mouse Models of Striated Muscular Pathologies

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Vignier, Nicolas ^a,b   Amor, Fatima ^c   Fogel, Paul ^d   Duvallet, Angélique ^c   Poupiot, Jérôme ^c   Charrier, Sabine ^c   Arock, Michel ^e   Montus, Marie ^c   Nelson, Isabelle ^a,b   Richard, Isabelle ^c,f   Carrier, Lucie ^a,b,g   Servais, Laurent ^h   Voit, Thomas ^a,b   Bonne, Gisèle ^a,b,e   Israeli, David ^c  

^a Sorbonne Université   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c GÉNÉTHON   (France)

^d Statistical Consultant   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f Centre National de la Recherche Scientifique   (France)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^h Institut de Myologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 1; MICRORNA 122; MICRORNA 125A; MICRORNA 125B; MICRORNA 133A; MICRORNA 133B; MICRORNA 142; MICRORNA 149; MICRORNA 151; MICRORNA 152; MICRORNA 193B; MICRORNA 195; MICRORNA 199A; MICRORNA 200; MICRORNA 200B; MICRORNA 206; MICRORNA 22; MICRORNA 26A; MICRORNA 301B; MICRORNA 30A; MICRORNA 30D; MICRORNA 30E; MICRORNA 31; MICRORNA 378; MICRORNA 429; MICRORNA 672; MICRORNA 709; MICRORNA 93; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE MODEL; DOWN REGULATION; DUCHENNE MUSCULAR DYSTROPHY; EMERY DREIFUSS MUSCULAR DYSTROPHY; EXPERIMENTAL MOUSE; GENE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LIMB GIRDLE MUSCULAR DYSTROPHY; LIMB GIRDLE MUSCULAR DYSTROPHY TYPE 2B; LIMB GIRDLE MUSCULAR DYSTROPHY TYPE 2C; LMNA GENE; MALE; MDX GENE; MOUSE; MUSCLE DISEASE; MYBPC3 GENE; NONHUMAN; NULL ALLELE; QUANTITATIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SGCA GENE; SGCG GENE; SKELETAL MUSCLE; UPREGULATION;

ANIMALS; DISEASE MODELS, ANIMAL; MICE; MICRORNAS; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES;

EID: 84873895776     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055281     Document Type: Article

References (46)

1. Emery AE, (2002) The muscular dystrophies. Lancet 359: 687-695.
2. Hermans MC, Pinto YM, Merkies IS, de Die-Smulders CE, Crijns HJ, et al. (2010) Hereditary muscular dystrophies and the heart. Neuromuscul Disord 20: 479-492.
3. Jacoby D, McKenna WJ, (2012) Genetics of inherited cardiomyopathy. Eur Heart J 33: 296-304.
4. Gasper MC, Gilchrist JM (2005) Creatine kinase: a review of its use in the diagnosis of muscle disease. Med Health R I 88: 398, 400-394.
5. Meune C, Wahbi K, Gobeaux C, Duboc D, Pecker F, et al. (2010) N-terminal Pro brain natriuretic peptide is a reliable biomarker of reduced myocardial contractility in patients with lamin A/C gene mutations. Int J Cardiol 151: 160-163.
6. Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
7. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401-1414.
8. Liang Y, Ridzon D, Wong L, Chen C, (2007) Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 8: 166.
9. Rosenfeld N, Aharonov R, Meiri E, Rosenwald S, Spector Y, et al. (2008) MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol 26: 462-469.
10. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
11. Eisenberg I, Eran A, Nishino I, Moggio M, Lamperti C, et al. (2007) Distinctive patterns of microRNA expression in primary muscular disorders. Proc Natl Acad Sci U S A 104: 17016-17021.
12. Sylvius N, Bonne G, Straatman K, Reddy T, Gant TW, et al. (2011) MicroRNA expression profiling in patients with lamin A/C-associated muscular dystrophy. Faseb J 25: 3966-3978.
13. Sucharov C, Bristow MR, Port JD, (2008) miRNA expression in the failing human heart: functional correlates. J Mol Cell Cardiol 45: 185-192.
14. McCarthy JJ, Esser KA, Andrade FH, (2007) MicroRNA-206 is overexpressed in the diaphragm but not the hindlimb muscle of mdx mouse. Am J Physiol Cell Physiol 293: C451-457.
15. Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, et al. (2008) Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol 141: 672-675.
16. Chen X, Ba Y, Ma L, Cai X, Yin Y, et al. (2008) Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18: 997-1006.
17. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, et al. (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 105: 10513-10518.
18. Gilad S, Meiri E, Yogev Y, Benjamin S, Lebanony D, et al. (2008) Serum microRNAs are promising novel biomarkers. PLoS One 3: e3148.
19. Creemers EE, Tijsen AJ, Pinto YM, (2011) Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? Circ Res 110: 483-495.
20. Reid G, Kirschner MB, van Zandwijk N, (2011) Circulating microRNAs: Association with disease and potential use as biomarkers. Crit Rev Oncol Hematol 80: 193-208.
21. Mestdagh P, Van Vlierberghe P, De Weer A, Muth D, Westermann F, et al. (2009) A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol 10: R64.
22. Joe H, Ward J, (1963) Hierarchical Grouping to Optimize an Objective Function. Journal of the American Statistical Association. Journal of the American Statistical Association 58: 236-244.
23. Benjamini Y, Hochberg Y, (1995) Controlling the False Discovery Rate: a Practical and Powerful Approach to Multiple Testing. Journal of the Royal Statistical Society 57: 289-300.
24. Duclos F, Straub V, Moore SA, Venzke DP, Hrstka RF, et al. (1998) Progressive muscular dystrophy in alpha-sarcoglycan-deficient mice. J Cell Biol 142: 1461-1471.
25. Hack AA, Ly CT, Jiang F, Clendenin CJ, Sigrist KS, et al. (1998) Gamma-sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin. J Cell Biol 142: 1279-1287.
26. Chapman VM, Miller DR, Armstrong D, Caskey CT, (1989) Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice. Proc Natl Acad Sci U S A 86: 1292-1296.
27. Ozawa E, Mizuno Y, Hagiwara Y, Sasaoka T, Yoshida M, (2005) Molecular and cell biology of the sarcoglycan complex. Muscle Nerve 32: 563-576.
28. Sveen ML, Thune JJ, Kober L, Vissing J, (2008) Cardiac involvement in patients with limb-girdle muscular dystrophy type 2 and Becker muscular dystrophy. Arch Neurol 65: 1196-1201.
29. Lancioni A, Rotundo IL, Kobayashi YM, D'Orsi L, Aurino S, et al. (2011) Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex. Hum Mol Genet 20: 4644-4654.
30. Towbin JA, (1998) The role of cytoskeletal proteins in cardiomyopathies. Curr Opin Cell Biol 10: 131-139.
31. Arimura T, Helbling-Leclerc A, Massart C, Varnous S, Niel F, et al. (2005) Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies. Hum Mol Genet 14: 155-169.
32. Worman HJ, Bonne G, (2007) "Laminopathies": a wide spectrum of human diseases. Exp Cell Res 313: 2121-2133.
33. Vignier N, Schlossarek S, Fraysse B, Mearini G, Kramer E, et al. (2009) Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice. Circ Res 105: 239-248.
34. Olivotto I, Girolami F, Sciagra R, Ackerman MJ, Sotgia B, et al. (2011) Microvascular function is selectively impaired in patients with hypertrophic cardiomyopathy and sarcomere myofilament gene mutations. J Am Coll Cardiol 58: 839-848.
35. Fougerousse F, Delezoide AL, Fiszman MY, Schwartz K, Beckmann JS, et al. (1998) Cardiac myosin binding protein C gene is specifically expressed in heart during murine and human development. Circ Res 82: 130-133.
36. Cacchiarelli D, Legnini I, Martone J, Cazzella V, D'Amico A, et al. (2011) miRNAs as serum biomarkers for Duchenne muscular dystrophy. EMBO Mol Med 3: 258-265.
37. Gagan J, Dey BK, Layer R, Yan Z, Dutta A, (2011) MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiation. J Biol Chem 286: 19431-19438.
38. Cacchiarelli D, Incitti T, Martone J, Cesana M, Cazzella V, et al. (2011) miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy. EMBO Rep 12: 136-141.
39. Pritchard CC, Kroh E, Wood B, Arroyo JD, Dougherty KJ, et al. (2012) Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev Res (Phila) 5: 492-497.
40. Mizuno H, Nakamura A, Aoki Y, Ito N, Kishi S, et al. (2011) Identification of muscle-specific microRNAs in serum of muscular dystrophy animal models: promising novel blood-based markers for muscular dystrophy. PLoS One 6: e18388.
41. Greco S, De Simone M, Colussi C, Zaccagnini G, Fasanaro P, et al. (2009) Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia. Faseb J 23: 3335-3346.
42. Townley-Tilson WH, Callis TE, Wang D, (2010) MicroRNAs 1, 133, and 206: critical factors of skeletal and cardiac muscle development, function, and disease. Int J Biochem Cell Biol 42: 1252-1255.
43. Cacchiarelli D, Martone J, Girardi E, Cesana M, Incitti T, et al. (2010) MicroRNAs involved in molecular circuitries relevant for the Duchenne muscular dystrophy pathogenesis are controlled by the dystrophin/nNOS pathway. Cell Metab 12: 341-351.
44. Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, et al. (2010) Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem 285: 17442-17452.
45. Muchir A, Pavlidis P, Decostre V, Herron AJ, Arimura T, et al. (2007) Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy. J Clin Invest 117: 1282-1293.
46. Fichtlscherer S, Zeiher AM, Dimmeler S, (2011) Circulating microRNAs: biomarkers or mediators of cardiovascular diseases? Arterioscler Thromb Vasc Biol 31: 2383-2390.