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Volumn 5, Issue 1, 2012, Pages 19-25

Nanomedical Theranostics in Cardiovascular Disease

Author keywords

Cardiac molecular imaging; Cardiovascular disease; Diagnostics; Nanoparticle; Theranostics; Therapeutics

Indexed keywords


EID: 84873882639     PISSN: 19419066     EISSN: 19419074     Source Type: Journal    
DOI: 10.1007/s12410-011-9120-6     Document Type: Review
Times cited : (50)

References (39)
  • 1
    • 79751531393 scopus 로고    scopus 로고
    • Heart Disease and Stroke Statistics-2011 Update: A Report From the American Heart Association
    • This article provides statistics of cardiovascular disease in the United States
    • Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM et al. Heart Disease and Stroke Statistics-2011 Update: A Report From the American Heart Association. Circulation. 123(4): e18-e209. This article provides statistics of cardiovascular disease in the United States.
    • Circulation , vol.123 , Issue.4
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3    Adams, R.J.4    Berry, J.D.5    Brown, T.M.6
  • 2
    • 27744522317 scopus 로고    scopus 로고
    • The forgotten majority: unfinished business in cardiovascular risk reduction
    • Libby P. The forgotten majority: unfinished business in cardiovascular risk reduction. J Am Coll Cardiol. 2005; 46(7): 1225-8.
    • (2005) J Am Coll Cardiol. , vol.46 , Issue.7 , pp. 1225-1228
    • Libby, P.1
  • 3
    • 77953033326 scopus 로고    scopus 로고
    • The vascular biology of atherosclerosis and imaging targets
    • Libby P, DiCarli M, Weissleder R. The vascular biology of atherosclerosis and imaging targets. J Nucl Med. 2010; 51 Suppl 1: 33S-7S.
    • (2010) J Nucl Med , vol.51 , Issue.SUPPL. 1
    • Libby, P.1    DiCarli, M.2    Weissleder, R.3
  • 4
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • This article explains the pathophysiology of atherosclerosis
    • Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006; 6(7): 508-19. This article explains the pathophysiology of atherosclerosis.
    • (2006) Nat Rev Immunol , vol.6 , Issue.7 , pp. 19-508
    • Hansson, G.K.1    Libby, P.2
  • 5
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: entering the mainstream
    • Allen TM, Cullis PR. Drug delivery systems: entering the mainstream. Science. 2004; 303(5665): 1818-22.
    • (2004) Science. , vol.303 , Issue.5665 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 6
    • 77955175216 scopus 로고    scopus 로고
    • Strategies in the design of nanoparticles for therapeutic applications
    • Petros RA, DeSimone JM. Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov. 2010; 9(8): 615-27.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.8 , pp. 615-627
    • Petros, R.A.1    DeSimone, J.M.2
  • 7
    • 33748579995 scopus 로고    scopus 로고
    • Angiogenesis in atherosclerosis: gathering evidence beyond speculation
    • Moulton KS. Angiogenesis in atherosclerosis: gathering evidence beyond speculation. Curr Opin Lipidol. 2006; 17(5): 548-55.
    • (2006) Curr Opin Lipidol. , vol.17 , Issue.5 , pp. 548-555
    • Moulton, K.S.1
  • 8
    • 77955653139 scopus 로고    scopus 로고
    • Theragnostics for tumor and plaque angiogenesis with perfluorocarbon nanoemulsions
    • Lanza GM, Winter PM, Caruthers SD, Hughes MS, Hu G, Schmieder AH, et al. Theragnostics for tumor and plaque angiogenesis with perfluorocarbon nanoemulsions. Angiogenesis. 2010; 13(2): 189-202.
    • (2010) Angiogenesis , vol.13 , Issue.2 , pp. 189-202
    • Lanza, G.M.1    Winter, P.M.2    Caruthers, S.D.3    Hughes, M.S.4    Hu, G.5    Schmieder, A.H.6
  • 11
    • 78649330634 scopus 로고    scopus 로고
    • Imaging and drug delivery using theranostic nanoparticles
    • Janib SM, Moses AS, MacKay JA. Imaging and drug delivery using theranostic nanoparticles. Adv Drug Deliv Rev. 2010; 62(11): 1052-63.
    • (2010) Adv Drug Deliv Rev. , vol.62 , Issue.11 , pp. 1052-1063
    • Janib, S.M.1    Moses, A.S.2    MacKay, J.A.3
  • 13
    • 0038179627 scopus 로고    scopus 로고
    • Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging
    • Kooi ME, Cappendijk VC, Cleutjens KB, Kessels AG, Kitslaar PJ, Borgers M, et al. Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation. 2003; 107(19): 2453-8.
    • (2003) Circulation. , vol.107 , Issue.19 , pp. 2453-2458
    • Kooi, M.E.1    Cappendijk, V.C.2    Cleutjens, K.B.3    Kessels, A.G.4    Kitslaar, P.J.5    Borgers, M.6
  • 14
    • 0035936540 scopus 로고    scopus 로고
    • Magnetic resonance imaging of atherosclerotic plaque with ultrasmall superparamagnetic particles of iron oxide in hyperlipidemic rabbits
    • Ruehm SG, Corot C, Vogt P, Kolb S, Debatin JF. Magnetic resonance imaging of atherosclerotic plaque with ultrasmall superparamagnetic particles of iron oxide in hyperlipidemic rabbits. Circulation. 2001; 103(3): 415-22.
    • (2001) Circulation. , vol.103 , Issue.3 , pp. 415-422
    • Ruehm, S.G.1    Corot, C.2    Vogt, P.3    Kolb, S.4    Debatin, J.F.5
  • 15
    • 38549156318 scopus 로고    scopus 로고
    • p38 MAPK inhibition reduces aortic ultrasmall superparamagnetic iron oxide uptake in a mouse model of atherosclerosis: MRI assessment
    • Morris JB, Olzinski AR, Bernard RE, Aravindhan K, Mirabile RC, Boyce R, et al. p38 MAPK inhibition reduces aortic ultrasmall superparamagnetic iron oxide uptake in a mouse model of atherosclerosis: MRI assessment. Arterioscler Thromb Vasc Biol. 2008; 28(2): 265-71.
    • (2008) Arterioscler Thromb Vasc Biol. , vol.28 , Issue.2 , pp. 265-271
    • Morris, J.B.1    Olzinski, A.R.2    Bernard, R.E.3    Aravindhan, K.4    Mirabile, R.C.5    Boyce, R.6
  • 16
    • 65649123771 scopus 로고    scopus 로고
    • The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study. Evaluation using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging in carotid disease
    • This is the first clinical study that uses USPIO-enhanced MRI to evaluate therapeutic effects of high-dose statin treatment. JM UK-I
    • Tang TY, Howarth SP, Miller SR, Graves MJ, Patterson AJ, JM UK-I et al. The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study. Evaluation using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging in carotid disease. J Am Coll Cardiol. 2009; 53(22): 2039-50. This is the first clinical study that uses USPIO-enhanced MRI to evaluate therapeutic effects of high-dose statin treatment.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.22 , pp. 50-2039
    • Tang, T.Y.1    Howarth, S.P.2    Miller, S.R.3    Graves, M.J.4    Patterson, A.J.5
  • 17
    • 79960940789 scopus 로고    scopus 로고
    • Peripheral artery disease. Part 2: medical and endovascular treatment
    • Weinberg MD, Lau JF, Rosenfield K, Olin JW. Peripheral artery disease. Part 2: medical and endovascular treatment. Nat Rev Cardiol. 2011; 8(8): 429-41.
    • (2011) Nat Rev Cardiol , vol.8 , Issue.8 , pp. 429-441
    • Weinberg, M.D.1    Lau, J.F.2    Rosenfield, K.3    Olin, J.W.4
  • 18
    • 77955119834 scopus 로고    scopus 로고
    • Molecular imaging of angiogenic therapy in peripheral vascular disease with alphanubeta3-integrin-targeted nanoparticles
    • Winter PM, Caruthers SD, Allen JS, Cai K, Williams TA, Lanza GM, et al. Molecular imaging of angiogenic therapy in peripheral vascular disease with alphanubeta3-integrin-targeted nanoparticles. Magn Reson Med. 2010; 64(2): 369-76.
    • (2010) Magn Reson Med , vol.64 , Issue.2 , pp. 369-376
    • Winter, P.M.1    Caruthers, S.D.2    Allen, J.S.3    Cai, K.4    Williams, T.A.5    Lanza, G.M.6
  • 19
    • 64249168271 scopus 로고    scopus 로고
    • The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: a review
    • O'Brien B, Carroll W. The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: a review. Acta Biomater. 2009; 5(4): 945-58.
    • (2009) Acta Biomater. , vol.5 , Issue.4 , pp. 945-958
    • O'Brien, B.1    Carroll, W.2
  • 20
    • 42149149916 scopus 로고    scopus 로고
    • Intramural delivery of rapamycin with alphavbeta3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury
    • Cyrus T, Zhang H, Allen JS, Williams TA, Hu G, Caruthers SD, et al. Intramural delivery of rapamycin with alphavbeta3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury. Arterioscler Thromb Vasc Biol. 2008; 28(5): 820-6.
    • (2008) Arterioscler Thromb Vasc Biol. , vol.28 , Issue.5 , pp. 820-826
    • Cyrus, T.1    Zhang, H.2    Allen, J.S.3    Williams, T.A.4    Hu, G.5    Caruthers, S.D.6
  • 21
    • 77952358653 scopus 로고    scopus 로고
    • Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields
    • Chorny M, Fishbein I, Yellen BB, Alferiev IS, Bakay M, Ganta S, et al. Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields. Proc Natl Acad Sci U S A. 2010; 107(18): 8346-51.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.18 , pp. 8346-8351
    • Chorny, M.1    Fishbein, I.2    Yellen, B.B.3    Alferiev, I.S.4    Bakay, M.5    Ganta, S.6
  • 22
    • 79851473442 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis
    • Kim J, Cao L, Shvartsman D, Silva EA, Mooney DJ. Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. Nano Lett. 2011; 11(2): 694-700.
    • (2011) Nano Lett. , vol.11 , Issue.2 , pp. 694-700
    • Kim, J.1    Cao, L.2    Shvartsman, D.3    Silva, E.A.4    Mooney, D.J.5
  • 23
    • 20344394410 scopus 로고    scopus 로고
    • A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II)
    • Ross AM, Gibbons RJ, Stone GW, Kloner RA, Alexander RW. A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II). J Am Coll Cardiol. 2005; 45(11): 1775-80.
    • (2005) J Am Coll Cardiol. , vol.45 , Issue.11 , pp. 1775-1780
    • Ross, A.M.1    Gibbons, R.J.2    Stone, G.W.3    Kloner, R.A.4    Alexander, R.W.5
  • 24
    • 60049093877 scopus 로고    scopus 로고
    • Prolonged targeting of ischemic/reperfused myocardium by liposomal adenosine augments cardioprotection in rats
    • Takahama H, Minamino T, Asanuma H, Fujita M, Asai T, Wakeno M, et al. Prolonged targeting of ischemic/reperfused myocardium by liposomal adenosine augments cardioprotection in rats. J Am Coll Cardiol. 2009; 53(8): 709-17.
    • (2009) J Am Coll Cardiol. , vol.53 , Issue.8 , pp. 709-717
    • Takahama, H.1    Minamino, T.2    Asanuma, H.3    Fujita, M.4    Asai, T.5    Wakeno, M.6
  • 25
    • 79959858154 scopus 로고    scopus 로고
    • Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis
    • Myerson J, He L, Lanza G, Tollefsen D, Wickline S. Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis. J Thromb Haemost. 2011; 9(7): 1292-300.
    • (2011) J Thromb Haemost , vol.9 , Issue.7 , pp. 1292-1300
    • Myerson, J.1    He, L.2    Lanza, G.3    Tollefsen, D.4    Wickline, S.5
  • 28
    • 0037180413 scopus 로고    scopus 로고
    • Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent implications for rational therapy of restenosis
    • Lanza GM, Yu X, Winter PM, Abendschein DR, Karukstis KK, Scott MJ, et al. Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent implications for rational therapy of restenosis. Circulation. 2002; 106(22): 2842-7.
    • (2002) Circulation. , vol.106 , Issue.22 , pp. 2842-2847
    • Lanza, G.M.1    Yu, X.2    Winter, P.M.3    Abendschein, D.R.4    Karukstis, K.K.5    Scott, M.J.6
  • 31
    • 78649932571 scopus 로고    scopus 로고
    • Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis
    • This study exemplifies that a theranostic approach can facilitate the development of nanotherapy
    • Lobatto ME, Fayad ZA, Silvera S, Vucic E, Calcagno C, Mani V et al. Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis. Mol Pharm. 2010; 7(6): 2020-9. This study exemplifies that a theranostic approach can facilitate the development of nanotherapy.
    • (2010) Mol Pharm , vol.7 , Issue.6 , pp. 9-2020
    • Lobatto, M.E.1    Fayad, Z.A.2    Silvera, S.3    Vucic, E.4    Calcagno, C.5    Mani, V.6
  • 32
    • 77956943493 scopus 로고    scopus 로고
    • A light-activated theranostic nanoagent for targeted macrophage ablation in inflammatory atherosclerosis
    • McCarthy JR, Korngold E, Weissleder R, Jaffer FA. A light-activated theranostic nanoagent for targeted macrophage ablation in inflammatory atherosclerosis. Small. 2010; 6(18): 2041-9.
    • (2010) Small. , vol.6 , Issue.18 , pp. 2041-2049
    • McCarthy, J.R.1    Korngold, E.2    Weissleder, R.3    Jaffer, F.A.4
  • 33
    • 79952934528 scopus 로고    scopus 로고
    • Standardization of models and methods used to assess nanoparticles in cardiovascular applications
    • Fitzgerald KT, Holladay CA, McCarthy C, Power KA, Pandit A, Gallagher WM. Standardization of models and methods used to assess nanoparticles in cardiovascular applications. Small. 2011; 7(6): 705-17.
    • (2011) Small , vol.7 , Issue.6 , pp. 705-717
    • Fitzgerald, K.T.1    Holladay, C.A.2    McCarthy, C.3    Power, K.A.4    Pandit, A.5    Gallagher, W.M.6
  • 34
    • 77957583441 scopus 로고    scopus 로고
    • Atherosclerotic lesions in mouse and man: is it the same disease?
    • Bentzon JF, Falk E. Atherosclerotic lesions in mouse and man: is it the same disease? Curr Opin Lipidol. 2010; 21(5): 434-40.
    • (2010) Curr Opin Lipidol , vol.21 , Issue.5 , pp. 434-440
    • Bentzon, J.F.1    Falk, E.2
  • 35
    • 79956319051 scopus 로고    scopus 로고
    • Progress and challenges in translating the biology of atherosclerosis
    • Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature. 2011; 473(7347): 317-25.
    • (2011) Nature , vol.473 , Issue.7347 , pp. 317-325
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 36
    • 66849141052 scopus 로고    scopus 로고
    • Current status of gadolinium toxicity in patients with kidney disease
    • Perazella MA. Current status of gadolinium toxicity in patients with kidney disease. Clin J Am Soc Nephrol. 2009; 4(2): 461-9.
    • (2009) Clin J Am Soc Nephrol. , vol.4 , Issue.2 , pp. 461-469
    • Perazella, M.A.1
  • 37
    • 17144416842 scopus 로고    scopus 로고
    • Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction
    • Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL. Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation. 2005; 111(14): 1800-5.
    • (2005) Circulation. , vol.111 , Issue.14 , pp. 1800-1805
    • Chen, J.1    Tung, C.H.2    Allport, J.R.3    Chen, S.4    Weissleder, R.5    Huang, P.L.6
  • 39
    • 84873863233 scopus 로고    scopus 로고
    • Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial
    • This is the first multicenter trial that uses noninvasive imaging to evaluate anti-atherosclerotic effects of a novel compound in patients
    • Fayad ZA, Mani V, Woodward M, Kallend D, Abt M, Burgess T et al. Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial. Lancet. This is the first multicenter trial that uses noninvasive imaging to evaluate anti-atherosclerotic effects of a novel compound in patients.
    • Lancet
    • Fayad, Z.A.1    Mani, V.2    Woodward, M.3    Kallend, D.4    Abt, M.5    Burgess, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.