-
1
-
-
0032104284
-
Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocar-cinoma: A study of 184 cases
-
Bostwick DG, Pacelli A, Blute M, et al. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocar-cinoma: a study of 184 cases. Cancer. 1998;82:2256-2261.
-
(1998)
Cancer.
, vol.82
, pp. 2256-2261
-
-
Bostwick, D.G.1
Pacelli, A.2
Blute, M.3
-
2
-
-
0022977209
-
Age-related changes in tissue levels of prostatic acid phosphatase and prostate specific antigen
-
Goldfarb DA, Stein BS, Shamszadeh M, et al. Age-related changes in tissue levels of prostatic acid phosphatase and prostate specific antigen. J Urol. 1986;136:1266-1269.
-
(1986)
J Urol.
, vol.136
, pp. 1266-1269
-
-
Goldfarb, D.A.1
Stein, B.S.2
Shamszadeh, M.3
-
3
-
-
0018595985
-
Purification of a human prostate specific antigen
-
Wang MC, Valenzuela LA, Murphy GP, et al. Purification of a human prostate specific antigen. Invest Urol. 1979;17:159-163.
-
(1979)
Invest Urol.
, vol.17
, pp. 159-163
-
-
Wang, M.C.1
Valenzuela, L.A.2
Murphy, G.P.3
-
4
-
-
0043160579
-
Recognition of PSA-derived peptide antigens by T cells from prostate cancer patients without any prior stimulation
-
Chakraborty NG, Stevens RL, Mehrotra S, et al. Recognition of PSA-derived peptide antigens by T cells from prostate cancer patients without any prior stimulation. Cancer Immunol Immunother. 2003;52: 497-505.
-
(2003)
Cancer Immunol Immunother.
, vol.52
, pp. 497-505
-
-
Chakraborty, N.G.1
Stevens, R.L.2
Mehrotra, S.3
-
5
-
-
22144484150
-
Androgen deprivation therapy for prostate cancer
-
Sharifi N, Gulley JL, Dahut WL. Androgen deprivation therapy for prostate cancer. JAMA. 2005;294:238-244.
-
(2005)
JAMA.
, vol.294
, pp. 238-244
-
-
Sharifi, N.1
Gulley, J.L.2
Dahut, W.L.3
-
6
-
-
84863548973
-
Sipuleucel-T (Provenge(R)) for castration-resistant prostate cancer
-
Di Lorenzo G, Ferro M, Buonerba C. Sipuleucel-T (Provenge(R)) for castration-resistant prostate cancer. BJU Int. 2012;110:E99-E104.
-
(2012)
BJU Int.
, vol.110
-
-
Di Lorenzo, G.1
Ferro, M.2
Buonerba, C.3
-
7
-
-
67650463335
-
PROSTVAC-VF: A vector-based vaccine targeting PSA in prostate cancer
-
Madan RA, Arlen PM, Mohebtash M, et al. PROSTVAC-VF: a vector-based vaccine targeting PSA in prostate cancer. Expert Opin Investig Drugs. 2009;18:1001-1011.
-
(2009)
Expert Opin Investig Drugs.
, vol.18
, pp. 1001-1011
-
-
Madan, R.A.1
Arlen, P.M.2
Mohebtash, M.3
-
8
-
-
34447123763
-
Granulocyte macrophage colony-stimulating factorYsecreting allogeneic cellular immuno-therapy for hormone-refractory prostate cancer
-
Small EJ, Sacks N, Nemunaitis J, et al. Granulocyte macrophage colony-stimulating factorYsecreting allogeneic cellular immuno-therapy for hormone-refractory prostate cancer. Clin Cancer Res. 2007;13:3883-3891.
-
(2007)
Clin Cancer Res.
, vol.13
, pp. 3883-3891
-
-
Small, E.J.1
Sacks, N.2
Nemunaitis, J.3
-
9
-
-
38049048619
-
Sipuleucel-T: A vaccine for metastatic, asymptomatic, androgen-independent prostate cancer
-
Patel PH, Kockler DR. Sipuleucel-T: a vaccine for metastatic, asymptomatic, androgen-independent prostate cancer. Ann Pharmacother. 2008;42:91-98.
-
(2008)
Ann Pharmacother.
, vol.42
, pp. 91-98
-
-
Patel, P.H.1
Kockler, D.R.2
-
10
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med. 1995;182:459-465.
-
(1995)
J Exp Med.
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
11
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
Waterhouse P, Penninger JM, Timms E, et al. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science. 1995;270:985-988.
-
(1995)
Science.
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
12
-
-
0029974509
-
Releasing the brakes on antitumor immune response
-
Pardoll D. Releasing the brakes on antitumor immune response. Science. 1996;271:1691.
-
(1996)
Science
, vol.271
, pp. 1691
-
-
Pardoll, D.1
-
13
-
-
0038153907
-
Cancer regression and autoimmu-nity induced by cytotoxic T lymphocyteYassociated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM, et al. Cancer regression and autoimmu-nity induced by cytotoxic T lymphocyteYassociated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA. 2003; 100:8372-8377.
-
(2003)
Proc Natl Acad Sci USA.
, vol.100
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
14
-
-
58049202334
-
Phase I/II study of ipilimumab for patients with metastatic melanoma
-
Weber JS, O'Day S, Urba W, et al. Phase I/II study of ipilimumab for patients with metastatic melanoma. J Clin Oncol. 2008;26:5950-5956.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 5950-5956
-
-
Weber, J.S.1
O'Day, S.2
Urba, W.3
-
15
-
-
78449237499
-
Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies
-
Ascierto PA, Simeone E, Sznol M, et al. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Semin Oncol. 2010;37:508-516.
-
(2010)
Semin Oncol.
, vol.37
, pp. 508-516
-
-
Ascierto, P.A.1
Simeone, E.2
Sznol, M.3
-
16
-
-
0036083073
-
Technology evaluation: APC-8015 dendreon
-
Rini BI. Technology evaluation: APC-8015, Dendreon. Curr Opin Mol Ther. 2002;4:76-79.
-
(2002)
Curr Opin Mol Ther.
, vol.4
, pp. 76-79
-
-
Rini, B.I.1
-
17
-
-
84873881305
-
Sipuleucel-T Immune Parameters Correlate with Survival: An Analysis of the Randomized Phase 3 Clinical Trials in Men with Castration-resistant Prostate Cancer [Published Online Ahead of Print August 3, 2012]
-
Sheikh NA, Petrylak D, Kantoff PW, et al. Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized phase 3 clinical trials in men with castration-resistant prostate cancer [published online ahead of print August 3, 2012]. Cancer Immunol Immunother. 2012.
-
(2012)
Cancer Immunol Immunother
-
-
Sheikh, N.A.1
Petrylak, D.2
Kantoff, P.W.3
-
18
-
-
0034043167
-
Priming tissue-specific cellular immunity in a phase i trial of autologous dendritic cells for prostate cancer
-
Burch PA, Breen JK, Buckner JC, et al. Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer. Clin Cancer Res. 2000;6:2175-2182.
-
(2000)
Clin Cancer Res.
, vol.6
, pp. 2175-2182
-
-
Burch, P.A.1
Breen, J.K.2
Buckner, J.C.3
-
19
-
-
0034554863
-
Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
-
Small EJ, Fratesi P, Reese DM, et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol. 2000;18:3894-3903.
-
(2000)
J Clin Oncol.
, vol.18
, pp. 3894-3903
-
-
Small, E.J.1
Fratesi, P.2
Reese, D.M.3
-
20
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small EJ, Schellhammer PF, Higano CS, et al. Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol. 2006;24:3089-3094.
-
(2006)
J Clin Oncol.
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
-
21
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammer PF, Small EJ, et al. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer. 2009;115:3670-3679.
-
(2009)
Cancer.
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
-
22
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363:411-422.
-
(2010)
N Engl J Med.
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
23
-
-
84873883304
-
-
FDA Approval for Sipuleucel-T Accessed October 21, 2012
-
FDA Approval for Sipuleucel-T. Available at: http://www.cancer.gov/ cancertopics/druginfo/fda-sipuleucel-T. Accessed October 21, 2012.
-
-
-
-
24
-
-
79960337024
-
Randomized trial of autolo-gous cellular immunotherapy with sipuleucel-T in androgen-dependent prostate cancer
-
Beer TM, Bernstein GT, Corman JM, et al. Randomized trial of autolo-gous cellular immunotherapy with sipuleucel-T in androgen-dependent prostate cancer. Clin Cancer Res. 2011;17:4558-4567.
-
(2011)
Clin Cancer Res.
, vol.17
, pp. 4558-4567
-
-
Beer, T.M.1
Bernstein, G.T.2
Corman, J.M.3
-
25
-
-
84873864005
-
-
Sipuleucel-T as Neoadjuvant Treatment in Prostate Cancer (NeoACT) Accessed October 21, 2012
-
Sipuleucel-T as Neoadjuvant Treatment in Prostate Cancer (NeoACT). Available at: http://clinicaltrials.gov/show/NCT00715104. Accessed October 21, 2012.
-
-
-
-
26
-
-
84857397717
-
Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer
-
Huber ML, Haynes L, Parker C, et al. Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer. J Natl Cancer Inst. 2012;104:273-279.
-
(2012)
J Natl Cancer Inst.
, vol.104
, pp. 273-279
-
-
Huber, M.L.1
Haynes, L.2
Parker, C.3
-
27
-
-
84864487608
-
Re: Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer
-
author reply 9-12
-
Kantoff PW, Higano CS, Small EJ, et al. Re: interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer. J Natl Cancer Inst. 2012;104:1107-1109; author reply 9-12.
-
(2012)
J Natl Cancer Inst.
, vol.104
, pp. 1107-1109
-
-
Kantoff, P.W.1
Higano, C.S.2
Small, E.J.3
-
28
-
-
84864428172
-
Re: Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer
-
author reply 9-12
-
Gulley JL, Leitman SF, Dahut W, et al. Re: interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer. J Natl Cancer Inst. 2012;104:1106; author reply 9-12.
-
(2012)
J Natl Cancer Inst.
, vol.104
, pp. 1106
-
-
Gulley, J.L.1
Leitman, S.F.2
Dahut, W.3
-
29
-
-
84866705588
-
Re: Interdisciplinary critique of sipuleucel-T as immuno-therapy in castration-resistant prostate cancer
-
author reply-l3
-
Drake CG. Re: interdisciplinary critique of sipuleucel-T as immuno-therapy in castration-resistant prostate cancer. J Natl Cancer Inst. 2012;104:1422; author reply-3.
-
(2012)
J Natl Cancer Inst.
, vol.104
, pp. 1422
-
-
Drake, C.G.1
-
30
-
-
77955080349
-
New therapies for castration-resistant prostate cancer
-
Longo DL. New therapies for castration-resistant prostate cancer. N Engl J Med. 2010;363:479-481.
-
(2010)
N Engl J Med.
, vol.363
, pp. 479-481
-
-
Longo, D.L.1
-
31
-
-
1842684059
-
Poxvirus vaccines for cancer and HIV therapy
-
Essajee S, Kaufman HL. Poxvirus vaccines for cancer and HIV therapy. Expert Opin Biol Ther. 2004;4:575-588.
-
(2004)
Expert Opin Biol Ther.
, vol.4
, pp. 575-588
-
-
Essajee, S.1
Kaufman, H.L.2
-
32
-
-
18644376211
-
Multiple costimulatory modalities enhance CTL avidity
-
Hodge JW, Chakraborty M, Kudo-Saito C, et al. Multiple costimulatory modalities enhance CTL avidity. J Immunol. 2005;174:5994-6004.
-
(2005)
J Immunol.
, vol.174
, pp. 5994-6004
-
-
Hodge, J.W.1
Chakraborty, M.2
Kudo-Saito, C.3
-
33
-
-
34548452131
-
Clinical safety of a viral vector based prostate cancer vaccine strategy
-
Arlen PM, Skarupa L, Pazdur M, et al. Clinical safety of a viral vector based prostate cancer vaccine strategy. J Urol. 2007;178:1515-1520.
-
(2007)
J Urol.
, vol.178
, pp. 1515-1520
-
-
Arlen, P.M.1
Skarupa, L.2
Pazdur, M.3
-
34
-
-
17444440950
-
A phase i trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer
-
Eder JP, Kantoff PW, Roper K, et al. A phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer. Clin Cancer Res. 2000;6:1632-1638.
-
(2000)
Clin Cancer Res.
, vol.6
, pp. 1632-1638
-
-
Eder, J.P.1
Kantoff, P.W.2
Roper, K.3
-
35
-
-
0034551730
-
Phase i study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
-
Marshall JL, Hoyer RJ, Toomey MA, et al. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J Clin Oncol. 2000;18:3964-3973.
-
(2000)
J Clin Oncol.
, vol.18
, pp. 3964-3973
-
-
Marshall, J.L.1
Hoyer, R.J.2
Toomey, M.A.3
-
36
-
-
0036787490
-
Phase i study of a vaccine using re-combinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer
-
Gulley J, Chen AP, Dahut W, et al. Phase I study of a vaccine using re-combinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer. Prostate. 2002;53: 109-117.
-
(2002)
Prostate.
, vol.53
, pp. 109-117
-
-
Gulley, J.1
Chen, A.P.2
Dahut, W.3
-
37
-
-
2942644684
-
Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): A trial of the Eastern Cooperative Oncology Group
-
Kaufman HL, Wang W, Manola J, et al. Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): a trial of the Eastern Cooperative Oncology Group. J Clin Oncol. 2004;22:2122-2132.
-
(2004)
J Clin Oncol.
, vol.22
, pp. 2122-2132
-
-
Kaufman, H.L.1
Wang, W.2
Manola, J.3
-
38
-
-
84863387673
-
Poxviral vectors for cancer immunotherapy
-
Kim JW, Gulley JL. Poxviral vectors for cancer immunotherapy. Expert Opin Biol Ther. 2012;12:463-478.
-
(2012)
Expert Opin Biol Ther.
, vol.12
, pp. 463-478
-
-
Kim, J.W.1
Gulley, J.L.2
-
39
-
-
77950473925
-
Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer
-
Gulley JL, Arlen PM, Madan RA, et al. Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer. Cancer Immunol Immunother. 2010;59:663-674.
-
(2010)
Cancer Immunol Immunother.
, vol.59
, pp. 663-674
-
-
Gulley, J.L.1
Arlen, P.M.2
Madan, R.A.3
-
40
-
-
77949895922
-
Overall survival analysis of a phase II randomized controlled trial of a poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer
-
Kantoff PW, Schuetz TJ, Blumenstein BA, et al. Overall survival analysis of a phase II randomized controlled trial of a poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol. 2010;28:1099-1105.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 1099-1105
-
-
Kantoff, P.W.1
Schuetz, T.J.2
Blumenstein, B.A.3
-
43
-
-
37349072460
-
Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis
-
Yang JC, Hughes M, Kammula U, et al. Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis. J Immunother. 2007;30:825-830.
-
(2007)
J Immunother.
, vol.30
, pp. 825-830
-
-
Yang, J.C.1
Hughes, M.2
Kammula, U.3
-
44
-
-
84860455345
-
Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: A phase 1 dose-escalation trial
-
Madan RA, Mohebtash M, Arlen PM, et al. Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial. Lancet Oncol. 2012;13:501-508.
-
(2012)
Lancet Oncol.
, vol.13
, pp. 501-508
-
-
Madan, R.A.1
Mohebtash, M.2
Arlen, P.M.3
-
45
-
-
77954801079
-
Improved survival with ipili-mumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipili-mumab in patients with metastatic melanoma. N Engl J Med. 2010;363: 711-723.
-
(2010)
N Engl J Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
46
-
-
34250223096
-
A pilot trial of CTLA-4 blockade with human antiYCTLA-4 in patients with hormone-refractory prostate cancer
-
Small EJ, Tchekmedyian NS, Rini BI, et al. A pilot trial of CTLA-4 blockade with human antiYCTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res. 2007;13:1810-1815.
-
(2007)
Clin Cancer Res.
, vol.13
, pp. 1810-1815
-
-
Small, E.J.1
Tchekmedyian, N.S.2
Rini, B.I.3
-
47
-
-
7444258053
-
Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes
-
Garnett CT, Palena C, Chakraborty M, et al. Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res. 2004;64:7985-7994.
-
(2004)
Cancer Res.
, vol.64
, pp. 7985-7994
-
-
Garnett, C.T.1
Palena, C.2
Chakraborty, M.3
-
48
-
-
84872195017
-
Ipilimumab in metastatic castrate-resistant prostate cancer: Results from an open-label, multicenter phase I/II study
-
Slovin SF, Hamid O, Tejwani S, et al. Ipilimumab in metastatic castrate-resistant prostate cancer: results from an open-label, multicenter phase I/II study. J Clin Oncol. 2012;30(S5):abstract 25.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.S5
, pp. 25
-
-
Slovin, S.F.1
Hamid, O.2
Tejwani, S.3
-
50
-
-
84873843155
-
-
Study of Immunotherapy to Treat Advanced Prostate Cancer Accessed October 1, 2012
-
Study of Immunotherapy to Treat Advanced Prostate Cancer. Available at: http://www.clinicaltrials.gov/ct2/show/NCT00861614. Accessed October 1, 2012.
-
-
-
-
51
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura H, Nose M, Hiai H, et al. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity. 1999;11:141-151.
-
(1999)
Immunity.
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
-
52
-
-
0035846991
-
Autoimmune dilated cardio-myopathy in PD-1 receptorYdeficient mice
-
Nishimura H, Okazaki T, Tanaka Y, et al. Autoimmune dilated cardio-myopathy in PD-1 receptorYdeficient mice. Science. 2001;291:319-322.
-
(2001)
Science.
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
-
53
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28:3167-3175.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
54
-
-
84862859820
-
Safety, activity, and immune correlates of antiYPD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of antiYPD-1 antibody in cancer. N Engl J Med. 2012;366: 2443-2454.
-
(2012)
N Engl J Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
55
-
-
84862903106
-
Safety and activity of antiY PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of antiY PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455-2465.
-
(2012)
N Engl J Med.
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
56
-
-
20944441967
-
Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer
-
Gulley JL, Arlen PM, Bastian A, et al. Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin Cancer Res. 2005;11:3353-3362.
-
(2005)
Clin Cancer Res.
, vol.11
, pp. 3353-3362
-
-
Gulley, J.L.1
Arlen, P.M.2
Bastian, A.3
-
57
-
-
77954951895
-
DNA vaccine encoding pros-tatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer
-
Becker JT, Olson BM, Johnson LE, et al. DNA vaccine encoding pros-tatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer. J Immunother. 2010;33:639-647.
-
(2010)
J Immunother.
, vol.33
, pp. 639-647
-
-
Becker, J.T.1
Olson, B.M.2
Johnson, L.E.3
-
58
-
-
36148973953
-
Kinetics of tumor-specific T-cell response development after active immunization in patients with HER-2/neu overexpressing cancers
-
Salazar LG, Coveler AL, Swensen RE, et al. Kinetics of tumor-specific T-cell response development after active immunization in patients with HER-2/neu overexpressing cancers. Clin Immunol. 2007;125:275-280.
-
(2007)
Clin Immunol.
, vol.125
, pp. 275-280
-
-
Salazar, L.G.1
Coveler, A.L.2
Swensen, R.E.3
-
59
-
-
0025101125
-
Prospective analysis of laser photophacofrag-mentation
-
Levin ML, Wyatt KD. Prospective analysis of laser photophacofrag- mentation. J Cataract Refract Surg. 1990;16:96-98.
-
(1990)
J Cataract Refract Surg.
, vol.16
, pp. 96-98
-
-
Levin, M.L.1
Wyatt, K.D.2
-
60
-
-
70350435441
-
Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer
-
Disis ML, Wallace DR, Gooley TA, et al. Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer. J Clin Oncol. 2009;27:4685-4692.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 4685-4692
-
-
Disis, M.L.1
Wallace, D.R.2
Gooley, T.A.3
-
61
-
-
77955097760
-
A viral vaccine encoding prostate-specific antigen induces antigen spreading to a common set of self-proteins in prostate cancer patients
-
Nesslinger NJ, Ng A, Tsang KY, et al. A viral vaccine encoding prostate-specific antigen induces antigen spreading to a common set of self-proteins in prostate cancer patients. Clin Cancer Res. 2010; 16:4046-4056.
-
(2010)
Clin Cancer Res.
, vol.16
, pp. 4046-4056
-
-
Nesslinger, N.J.1
Ng, A.2
Tsang, K.Y.3
-
62
-
-
4544252430
-
Humoral epitope-spreading following immunization with a HER-2/neu peptide based vaccine in cancer patients
-
Disis ML, Goodell V, Schiffman K, et al. Humoral epitope-spreading following immunization with a HER-2/neu peptide based vaccine in cancer patients. J Clin Immunol. 2004;24:571-578.
-
(2004)
J Clin Immunol.
, vol.24
, pp. 571-578
-
-
Disis, M.L.1
Goodell, V.2
Schiffman, K.3
-
63
-
-
72449127534
-
Therapeutic vaccines in metastatic castration-resistant prostate cancer: Principles in clinical trial design
-
Madan RA, Mohebtash M, Schlom J, et al. Therapeutic vaccines in metastatic castration-resistant prostate cancer: principles in clinical trial design. Expert Opin Biol Ther. 2010;10:19-28.
-
(2010)
Expert Opin Biol Ther.
, vol.10
, pp. 19-28
-
-
Madan, R.A.1
Mohebtash, M.2
Schlom, J.3
-
64
-
-
41949104346
-
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
-
Scher HI, Halabi S, Tannock I, et al. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol. 2008;26:1148-1159.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
-
65
-
-
77957273591
-
Improved endpoints for cancer immunotherapy trials
-
Hoos A, Eggermont AM, Janetzki S, et al. Improved endpoints for cancer immunotherapy trials. J Natl Cancer Inst. 2010;102:1388-1397.
-
(2010)
J Natl Cancer Inst.
, vol.102
, pp. 1388-1397
-
-
Hoos, A.1
Eggermont, A.M.2
Janetzki, S.3
-
66
-
-
41149164895
-
Adenovirus MART-1-engineered autologous dendritic cell vaccine for metastatic melanoma
-
Butterfield LH, Comin-Anduix B, Vujanovic L, et al. Adenovirus MART-1-engineered autologous dendritic cell vaccine for metastatic melanoma. J Immunother. 2008;31:294-309.
-
(2008)
J Immunother.
, vol.31
, pp. 294-309
-
-
Butterfield, L.H.1
Comin-Anduix, B.2
Vujanovic, L.3
-
67
-
-
79151474414
-
Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre-versus post-vaccination
-
Vergati M, Cereda V, Madan RA, et al. Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre-versus post-vaccination. Cancer Immunol Immunother. 2011;60:197-206.
-
(2011)
Cancer Immunol Immunother.
, vol.60
, pp. 197-206
-
-
Vergati, M.1
Cereda, V.2
Madan, R.A.3
-
68
-
-
77957787538
-
Therapeutic cancer vaccines in prostate cancer: The paradox of improved survival without changes in time to progression
-
Madan RA, Gulley JL, Fojo T, et al. Therapeutic cancer vaccines in prostate cancer: the paradox of improved survival without changes in time to progression. Oncologist. 2010;15:969-975.
-
(2010)
Oncologist.
, vol.15
, pp. 969-975
-
-
Madan, R.A.1
Gulley, J.L.2
Fojo, T.3
-
69
-
-
79951826832
-
Tumor regression and growth rates determined in five intramural NCI prostate cancer trials: The growth rate constant as an indicator of therapeutic efficacy
-
Stein WD, Gulley JL, Schlom J, et al. Tumor regression and growth rates determined in five intramural NCI prostate cancer trials: the growth rate constant as an indicator of therapeutic efficacy. Clin Cancer Res. 2011;17:907-917.
-
(2011)
Clin Cancer Res.
, vol.17
, pp. 907-917
-
-
Stein, W.D.1
Gulley, J.L.2
Schlom, J.3
-
70
-
-
55049137067
-
Tumor growth rates derived from data for patients in a clinical trial correlate strongly with patient survival: A novel strategy for evaluation of clinical trial data
-
Stein WD, Figg WD, Dahut W, et al. Tumor growth rates derived from data for patients in a clinical trial correlate strongly with patient survival: a novel strategy for evaluation of clinical trial data. Oncologist. 2008;13:1046-1054.
-
(2008)
Oncologist.
, vol.13
, pp. 1046-1054
-
-
Stein, W.D.1
Figg, W.D.2
Dahut, W.3
-
71
-
-
55049109179
-
Bevacizumab reduces the growth rate constants of renal carcinomas: A novel algorithm suggests early discontinuation of bevacizumab resulted in a lack of survival advantage
-
Stein WD, Yang J, Bates SE, et al. Bevacizumab reduces the growth rate constants of renal carcinomas: a novel algorithm suggests early discontinuation of bevacizumab resulted in a lack of survival advantage. Oncologist. 2008;13:1055-1062.
-
(2008)
Oncologist.
, vol.13
, pp. 1055-1062
-
-
Stein, W.D.1
Yang, J.2
Bates, S.E.3
-
72
-
-
84861178107
-
Clinical evaluation of TRICOM vector therapeutic cancer vaccines
-
Madan RA, Bilusic M, Heery C, et al. Clinical evaluation of TRICOM vector therapeutic cancer vaccines. Semin Oncol. 2012;39:296-304.
-
(2012)
Semin Oncol.
, vol.39
, pp. 296-304
-
-
Madan, R.A.1
Bilusic, M.2
Heery, C.3
-
73
-
-
84873824001
-
A phase II study of PROSTVAC-V (vaccinia)/TRICOM and PROSTVAC-F (fowlpox)/TRICOM with GM-CSF in patients with PSA progression after local therapy for prostate cancer: Results of ECOG 9802 [poster]
-
Orlando, FL, February 26-28, 2009. Abstract 108
-
Chakraborty DiPaola R, Chen Y, Bubley G, et al. A phase II study of PROSTVAC-V (vaccinia)/TRICOM and PROSTVAC-F (fowlpox)/TRICOM with GM-CSF in patients with PSA progression after local therapy for prostate cancer: results of ECOG 9802 [poster]. Presented at the ASCO Genitourinary Cancers Symposium, Orlando, FL, February 26-28, 2009. Abstract 108.
-
Presented at the ASCO Genitourinary Cancers Symposium
-
-
Chakraborty Dipaola, R.1
Chen, Y.2
Bubley, G.3
-
74
-
-
3042569675
-
External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing
-
Chakraborty M, Abrams SI, Coleman CN, et al. External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing. Cancer Res. 2004;64:4328-4337.
-
(2004)
Cancer Res.
, vol.64
, pp. 4328-4337
-
-
Chakraborty, M.1
Abrams, S.I.2
Coleman, C.N.3
-
75
-
-
0037942745
-
Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy
-
Chakraborty M, Abrams SI, Camphausen K, et al. Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. J Immunol. 2003;170:6338-6347.
-
(2003)
J Immunol.
, vol.170
, pp. 6338-6347
-
-
Chakraborty, M.1
Abrams, S.I.2
Camphausen, K.3
-
76
-
-
37349051718
-
Molecular characteristics of immunogenic cancer cell death
-
Tesniere A, Panaretakis T, Kepp O, et al. Molecular characteristics of immunogenic cancer cell death. Cell Death Differ. 2008;15:3-12.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 3-12
-
-
Tesniere, A.1
Panaretakis, T.2
Kepp, O.3
-
77
-
-
84857815877
-
Immunologic correlates of the abscopal effect in a patient with melanoma
-
Postow MA, Callahan MK, Barker CA, et al. Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med. 2012;366:925-931.
-
(2012)
N Engl J Med.
, vol.366
, pp. 925-931
-
-
Postow, M.A.1
Callahan, M.K.2
Barker, C.A.3
-
78
-
-
34547700498
-
Impact of androgen-deprivation therapy on the immune system: Implications for combination therapy of prostate cancer
-
Aragon-Ching JB, Williams KM, Gulley JL. Impact of androgen-deprivation therapy on the immune system: implications for combination therapy of prostate cancer. Front Biosci. 2007;12:4957-4971.
-
(2007)
Front Biosci.
, vol.12
, pp. 4957-4971
-
-
Aragon-Ching, J.B.1
Williams, K.M.2
Gulley, J.L.3
-
79
-
-
0035807916
-
T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer
-
Mercader M, Bodner BK, Moser MT, et al. T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer. Proc Natl Acad Sci USA. 2001;98:14565-14570.
-
(2001)
Proc Natl Acad Sci USA.
, vol.98
, pp. 14565-14570
-
-
Mercader, M.1
Bodner, B.K.2
Moser, M.T.3
-
80
-
-
23844486206
-
Effects of castration on thy-mocyte development in two different models of thymic involution
-
Heng TS, Goldberg GL, Gray DH, et al. Effects of castration on thy-mocyte development in two different models of thymic involution. J Immunol. 2005;175:2982-2993.
-
(2005)
J Immunol.
, vol.175
, pp. 2982-2993
-
-
Heng, T.S.1
Goldberg, G.L.2
Gray, D.H.3
-
81
-
-
20244380618
-
Androgen ablation mitigates tolerance to a prostate/prostate cancerYrestricted antigen
-
Drake CG, Doody AD, Mihalyo MA, et al. Androgen ablation mitigates tolerance to a prostate/prostate cancerYrestricted antigen. Cancer Cell. 2005;7:239-249.
-
(2005)
Cancer Cell.
, vol.7
, pp. 239-249
-
-
Drake, C.G.1
Doody, A.D.2
Mihalyo, M.A.3
-
82
-
-
84863340958
-
A randomized phase II study of flutamide with or without PSA-TRICOM in nonmetastatic castration-resistant prostate cancer
-
Bilusic M, Gulley J, Heery C, et al. A randomized phase II study of flutamide with or without PSA-TRICOM in nonmetastatic castration-resistant prostate cancer. J Clin Oncol. 2011;29(S7). Abstract 163.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.S7
, pp. 163
-
-
Bilusic, M.1
Gulley, J.2
Heery, C.3
-
83
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher HI, Fizazi K, Saad F, et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med. 2012;367: 1187-1197.
-
(2012)
N Engl J Med.
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
84
-
-
84873818378
-
-
L-BLP25 (Stimuvax) in Prostate Cancer Accessed October 21, 2012
-
L-BLP25 (Stimuvax) in Prostate Cancer. Available at: http://www. clinicaltrials.gov/ct2/show/NCT01496131. Accessed October 21, 2012.
-
-
-
-
85
-
-
73349104629
-
Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations
-
Boehm AL, Higgins J, Franzusoff A, et al. Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations. Cancer Immunol Immunother. 2010;59:397-408.
-
(2010)
Cancer Immunol Immunother.
, vol.59
, pp. 397-408
-
-
Boehm, A.L.1
Higgins, J.2
Franzusoff, A.3
-
86
-
-
84860436621
-
Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: A phase 1 dose-escalation trial
-
van den Eertwegh AJ, Versluis J, van den Berg HP, et al. Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial. Lancet Oncol. 2012;13:509-517.
-
(2012)
Lancet Oncol.
, vol.13
, pp. 509-517
-
-
Van Den Eertwegh, A.J.1
Versluis, J.2
Van Den Berg, H.P.3
-
87
-
-
84873822896
-
A phase 2 randomized trial of docetaxel alone or in combination with the therapeutic cancer vaccine, CEAYMUC-1YTRICOM
-
Vienna, Austria, September 28-October 2, 2012. Abstract LBA14
-
Heery C, Ibrahim N, Madan RA, et al. A phase 2 randomized trial of docetaxel alone or in combination with the therapeutic cancer vaccine, CEAYMUC-1YTRICOM. Presented at the 37th Congress of the European Society of Medical Oncology, Vienna, Austria, September 28-October 2, 2012. Abstract LBA14.
-
37th Congress of the European Society of Medical Oncology
-
-
Heery, C.1
Ibrahim, N.2
Madan, R.A.3
-
88
-
-
84900475271
-
Interim analysis of a phase II randomized clinical trial of samrium-153 with or without PSA-TRICOM vaccine in metastatic castration-resistant prostate cancer after docetaxel
-
Heery C, Madan RA, Bilusic M, et al. Interim analysis of a phase II randomized clinical trial of samrium-153 with or without PSA-TRICOM vaccine in metastatic castration-resistant prostate cancer after docetaxel. J Clin Oncol. 2012;30. Abstract 2526.
-
(2012)
J Clin Oncol.
, vol.30
, pp. 2526
-
-
Heery, C.1
Madan, R.A.2
Bilusic, M.3
|