Investigation of neovascularization in three-dimensional porous scaffolds in vivo by a combination of multiscale photoacoustic microscopy and optical coherence tomography

Tissue Engineering - Part C: Methods

Volumn 19, Issue 3, 2013, Pages 196-204

  Cai, Xin ^a   Zhang, Yu ^a,b   Li, Li ^a,c   Choi, Sung Wook ^a,d   MacEwan, Matthew R ^a   Yao, Junjie ^a   Kim, Chulhong ^a,e   Xia, Younan ^a,b   Wang, Lihong V ^a  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^b Emory University   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d The Catholic University of Korea   (South Korea)

^e University at Buffalo SUNY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID SYSTEMS; MAMMALS; PHOTOACOUSTIC MICROSCOPY; SCAFFOLDS (BIOLOGY); THREE DIMENSIONAL; THREE DIMENSIONAL COMPUTER GRAPHICS;

GRAND CHALLENGE; HIGH SPATIAL RESOLUTION; HISTOLOGIC ANALYSIS; IN-VIVO; INVERSE OPAL; LATERAL RESOLUTION; MOUSE MODELS; MULTISCALES; NEOVASCULARIZATION; OPTICAL SCATTERING; RED BLOOD CELL; THREE-DIMENSIONAL (3D) SCAFFOLDS; THREE-DIMENSIONAL POROUS SCAFFOLDS; VASCULATURE;

OPTICAL TOMOGRAPHY;

TISSUE SCAFFOLD;

ANGIOGENESIS; ANIMAL; ARTICLE; BLOOD VESSEL; CYTOLOGY; GROWTH, DEVELOPMENT AND AGING; METHODOLOGY; MICROSCOPY; MOUSE; NUDE MOUSE; OPTICAL COHERENCE TOMOGRAPHY; PHOTOACOUSTICS; PHYSIOLOGY; POROSITY;

ANIMALS; BLOOD VESSELS; MICE; MICE, NUDE; MICROSCOPY; NEOVASCULARIZATION, PHYSIOLOGIC; PHOTOACOUSTIC TECHNIQUES; POROSITY; TISSUE SCAFFOLDS; TOMOGRAPHY, OPTICAL COHERENCE;

MLCS; MLOWN;

EID: 84873853755     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2012.0326     Document Type: Article

References (38)

1. Langer, R., and Vacanti, J. Tissue engineering. Science 260, 920, 1993.
2. Langer, R. Tissue engineering: status and challenges. E-Biomed J Regen Med 1, 5, 2004.
3. Langer, R. Perspectives and challenges in tissue engineering and regenerative medicine. Adv Mater 21, 3235, 2009.
4. Ma, P.X. Scaffolds for tissue fabrication. Mater Today 7, 30, 2004.
5. Hollister, S.J. Porous scaffold design for tissue engineering. Nat Mater 4, 518, 2005.
6. Patel, Z.S., and Mikos, A.G. Angiogenesis with biomaterial-based drug-and cell-delivery systems. J Biomater Sci Polym Ed 15, 701, 2004.
7. Lovett, M., Lee, K., Edwards, A., and Kaplan, D.L. Vascu-larization strategies for tissue engineering. Tissue Eng Part B Rev 15, 353, 2009.
8. Schmidt, C., Bezuidenhout, D., Beck, M., Van der Merve, E., Zilla, P., and Davies, N. Rapid three-dimensional quantification of VEGF-induced scaffold neovascularisation by mi-crocomputed tomography. Biomaterials 30, 5959, 2009.
9. Perng, C.-K., Wang, Y.-J., Tsi, C.-H., and Ma, H. In vivo angiogenesis effect of porous collagen scaffold with hya-luronic acid oligosaccharides. J Surg Res 168, 9, 2011.
10. Dumas, D., Riquelme, B., Werkmeister, E., Isla, N.D., and Stoltz, J.F. Multimodality of microscopy imaging applied to cartilage tissue engineering. In: Buckwalter, J.A., Lotz, M., and Stoltz, J.-F., eds. Biomedical and Health Research. Amsterdam: IOS Press, 2007, pp. 254-266.
11. Kim, C., Favazza, C., and Wang, L.V. In vivo photoacoustic tomography of chemicals: high-resolution functional and molecular optical imaging at new depths. Chem Rev 110, 2756, 2010.
12. Zhang, H.F., Maslov, K., Stoica, G., and Wang, L.V. Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging. Nat Biotechnol 24, 848, 2006.
13. Zhang, Y., Cai, X., Choi, S.-W., Kim, C., Wang, L.V., and Xia, Y. Chronic label-free volumetric photoacoustic microscopy of melanoma cells in three-dimensional porous scaffolds. Biomaterials 31, 8651, 2010.
14. Zhang, Y., Cai, X., Wang, Y., Zhang, C., Li, L., Choi, S.-W., et al. Noninvasive photoacoustic microscopy of living cells in two and three dimensions through enhancement by a metabolite dye. Angew Chem Int Ed 123, 7497, 2011.
15. Choi, S.-W., Cheong, I.W., Kim, J.-K., and Xia, Y. Preparation of uniform microspheres using a simple fluidic device and their crystallization into close-packed lattice. Small 5, 454, 2009.
16. Choi, S.-W., Zhang, Y., and Xia, Y. Fabrication of microbeads with a controllable hollow interior and porous wall using a capillary fluidic device. Adv Funct Mater 19, 2943, 2009.
17. Li, L., Maslov, K., Ku, G., and Wang, L.V. Three-dimensional combined photoacoustic and optical coherence microscopy for in vivo microcirculation studies. Opt Express 17, 16450, 2009.
18. Zhang, H.F., Maslov, K., and Wang, L.V. Automatic algorithm for skin profile detection in photoacoustic microscopy. J Biomed Opt 14, 024050, 2009.
19. Choi, S.-W., Zhang, Y., Thomopoulos, S., and Xia, Y. In vitro mineralization by preosteoblasts in poly(D, L-lactide-co-glycolide) inverse opal scaffolds reinforced with hydroxy-apatite nanoparticles. Langmuir 26, 12126, 2010.
20. Choi, S-W., Zhang, Y., and Xia, Y. Three-dimensional scaffolds for tissue engineering: the importance of uniformity in pore size and structure. Langmuir 26, 19001, 2010.
21. Zhang, Y., Choi, S.-W., and Xia, Y. Modifying the pores of an inverse opal scaffold with chitosan microstructures for truly three-dimensional cell culture. Macromol Rapid Commun 33, 296, 2012.
22. Choi, S.-W., Zhang, Y., MacEwan, M.R., and Xia, Y. Neo-vascularization in biodegradable inverse opal scaffolds with uniform and precisely controlled pore sizes. Adv Healthcare Mater, 2012 [Epub ahead of print]; DOI: adhm.201200106.
23. Zhang, Y., and Xia, Y. Formation of embryoid bodies with controlled sizes and maintained pluripotency in three-dimensional inverse opal scaffolds. Adv Funct Mater 22, 121, 2012.
24. Jain, R.K., Au P., Tam, J., Duda, D.G., and Fukumura, D. Engineering vascularized tissue. Nat Biotechnol 23, 821, 2005.
25. Moon, J.J., and West J. L. Vascularization of engineered tissues: approaches to promote angio-genesis in biomaterials. Curr Top Med Chem 8, 300, 2008.
26. Hu, S., Maslov, K., and Wang, L.V. Second-generation optical-resolution photoacoustic microscopy with improved sensitivity and speed. Opt Lett 36, 1134, 2011.
27. Yao, J., Maslov, K., Zhang, Y., Xia, Y., and Wang, L.V. Label-free oxygen-metabolic photoacoustic microscopy in vivo. J Biomed Opt 16, 076003, 2011.
28. Yang, Y., Dubois, A., Qin, X.-P., Li, J., Haj, A.E.I., and Wang, R.K. Investigation of optical coherence tomography as an imaging modality in tissue engineering. Phys Med Biol 51, 1649, 2006.
29. Wang, L.V. Multiscale photoacoustic microscopy and computed tomography. Nat Photon 3, 503, 2009.
30. Ku, G., and Wang, L.V. Deeply penetrating photoacoustic tomography in biological tissues enhanced with an optical contrast agent. Opt Lett 30, 507, 2005.
31. Kim, C., Erpelding, T.N., Jankovic, L., Pashley, M.D., and Wang, L.V. Deeply penetrating in vivo photoacoustic imaging using a clinical ultrasound array system. Biomed Opt Express 1, 278, 2010.
32. Jabbarzadeh, E., Starnes, T., Khan, Y.M., Jiang, T., Wirtel, A.J., Deng, M., et al. Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: a combined gene therapy-cell transplantation approach. Proc Natl Acad Sci USA 105, 11099, 2008.
33. Kalka, C., Masuda, H., Takahashi, T., Kalka-Moll, W.M., Silver, M., Kearney, M., et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neo-vascularization. Proc Natl Acad Sci USA 97, 3422, 2000.
34. Levenberg, S., Golub, J.S., Amit, M., Itskovitz-Eldor, J., and Langer, R. Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci USA 99, 4391, 2002.
35. L'Heureux, N., Dusserre, N., Konig, G., Victor, B., Keire, P., Wight, T.N., et al. Human tissue-engineered blood vessels for adult arterial revascularization. Nat Med 12, 361, 2006.
36. Yao, J., and Wang, L.V. Transverse flow imaging based on photoacoustic Doppler bandwidth broadening. J Biomed Opt 15, 021304, 2010.
37. Yao, J., Maslov, K.I., Shi, Y., Taber, L.A., and Wang, L.V. In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth. Opt Lett 35, 1419, 2010.
38. Zhang, H.F., Maslov, K., Sivaramakrishnan, M., Stoica, G., and Wang, L.V. Imaging of hemoglobin oxygen saturation variations in single vessels in vivo using photoacoustic microscopy. Appl Phys Lett 90, 053901, 2007.