A Statistical Framework for Decision Making in Confirmatory Multipopulation Tailoring Clinical Trials

Drug Information Journal

Volumn 46, Issue 6, 2012, Pages 647-656

  Millen, Brian A ^a   Dmitrienko, Alex ^b   Ruberg, Stephen ^a   Shen, Lei ^a  

^a ELI LILLY AND COMPANY   (United States)

^b IQVIA   (United States)

Author keywords

influence condition; interaction condition; subgroup analysis; tailored therapy; type I error rate

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PLACEBO;

ANALYTICAL ERROR; ARTICLE; BAYES THEOREM; CONCEPTUAL FRAMEWORK; DECISION MAKING; FOOD AND DRUG ADMINISTRATION; HUMAN; LUNG NON SMALL CELL CANCER; NULL HYPOTHESIS; PHASE 3 CLINICAL TRIAL (TOPIC); POPULATION DYNAMICS; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; QUALITATIVE ANALYSIS; REGISTRATION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STUDY DESIGN;

EID: 84873817347     PISSN: 00928615     EISSN: None     Source Type: Journal    
DOI: 10.1177/0092861512454116     Document Type: Article

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