Albumin domain II mutant with high bilirubin binding affinity has a great potential as serum bilirubin excretion enhancer for hyperbilirubinemia treatment

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 4, 2013, Pages 2917-2923

  Minomo, Ai ^a   Ishima, Yu ^a   Chuang, Victor T G ^b   Suwa, Yoshiaki ^a   Kragh Hansen, Ulrich ^c   Narisoko, Toru ^a   Morioka, Hiroshi ^a   Maruyama, Toru ^a   Otagiri, Masaki ^a,d  

^a KUMAMOTO UNIVERSITY   (Japan)

^b CURTIN UNIVERSITY   (Australia)

^c AARHUS UNIVERSITY   (Denmark)

^d SOJO UNIVERSITY   (Japan)

Author keywords

Bilirubin; Human serum albumin; Hyperbilirubinemia; Liver failure; Phage display

Indexed keywords

BILIRUBIN; HUMAN SERUM ALBUMIN; PAN3 3 13; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIRUBIN BLOOD LEVEL; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; HYPERBILIRUBINEMIA; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT RESPONSE;

AMINO ACID SEQUENCE; ANIMALS; BILIRUBIN; HUMANS; HYPERBILIRUBINEMIA; MICE; MICE, INBRED ICR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; SERUM ALBUMIN; SURFACE PLASMON RESONANCE;

MUS;

EID: 84873745129     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.01.006     Document Type: Article

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