Improvement of the dispersibility of spray-dried budesonide powders using leucine in an ethanol-water cosolvent system

Powder Technology

Volumn 236, Issue , 2013, Pages 171-178

  Boraey, Mohammed A ^a   Hoe, Susan ^a   Sharif, Hajar ^a   Miller, Danforth P ^b   Lechuga Ballesteros, David ^c   Vehring, Reinhard ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NOVARTIS PHARMA AG   (Switzerland)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Cosolvent; Dry powder inhaler; Leucine; Particle engineering; Respiratory drug delivery; Spray drying

Indexed keywords

COSOLVENTS; DRY POWDER INHALER; LEUCINE; PARTICLE ENGINEERING; RESPIRATORY DRUG DELIVERIES;

DRUG DELIVERY; ETHANOL; POWDERS;

AMINO ACIDS;

ALCOHOL; BUDESONIDE; LEUCINE; WATER;

ARTICLE; DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENCAPSULATION; MORPHOLOGY; PARTICLE SIZE; POWDER; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; X RAY POWDER DIFFRACTION;

EID: 84873744963     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.02.047     Document Type: Article

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