A novel neurofibromin (NF1) interaction with the leucine-rich pentatricopeptide repeat motif-containing protein links neurofibromatosis type 1 and the french canadian variant of Leigh's syndrome in a common molecular complex

Journal of Neuroscience Research

Volumn 91, Issue 4, 2013, Pages 494-505

  Arun, Vedant ^a,b   Wiley, Joseph C ^a   Kaur, Harpreet ^c   Kaplan, David R ^a,b   Guha, Abhijit ^a,b,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

^d TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Leigh's Syndrome French Canadian variant; Leucine Rich Pentatricopeptide Repeat motif Containing protein; Neurofibromatosis type 1; Neurofibromin; RNA granules

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; KINESIN; KINESIN 5B; LEUCINE; LEUCINE RICH PENTATRICOPEPTIDE REPEAT MOTIF CONTAINING PROTEIN; MESSENGER RNA; MYELIN BASIC PROTEIN; NEUROFIBROMIN; STAUFEN 1; TETRATRICOPEPTIDE REPEAT PROTEIN; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CANADA; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE MUTATION; HUMAN; HUMAN CELL; LEIGH DISEASE; LEIGH SYNDROME FRENCH CANADIAN VARIANT; MOLECULAR DYNAMICS; NEUROFIBROMATOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; TETRATRICOPEPTIDE REPEAT;

CELL LINE, TUMOR; CYTOCHROME-C OXIDASE DEFICIENCY; HUMANS; LEIGH DISEASE; MITOCHONDRIAL PROTEINS; MUTATION; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; PROTEIN STRUCTURE, TERTIARY; RAS GTPASE-ACTIVATING PROTEINS; SCHWANN CELLS;

EID: 84873734871     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23189     Document Type: Article

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