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Volumn 44, Issue 3, 2013, Pages 336-345

The pluripotent renal stem cell regulator SIX2 is activated in renal neoplasms and influences cellular proliferation and migration

Author keywords

Blastema; Nephroblastoma; Renal cell carcinoma; SIX2

Indexed keywords

HOX PROTEIN; PROTEIN; PROTEIN HOXA11; PROTEIN HOXC11; PROTEIN HOXD11; PROTEIN SIX2; UNCLASSIFIED DRUG; WNT PROTEIN; WNT11 PROTEIN; WNT9B PROTEIN;

EID: 84873733835     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2012.05.021     Document Type: Article
Times cited : (24)

References (35)
  • 2
    • 0023279638 scopus 로고
    • Ultrastructure and histogenesis of the renal tumors of childhood: An overview
    • G.W. Mierau, J.B. Beckwith, and D.A. Weeks Ultrastructure and histogenesis of the renal tumors of childhood: an overview Ultrastruct Pathol 11 1987 313 333
    • (1987) Ultrastruct Pathol , vol.11 , pp. 313-333
    • Mierau, G.W.1    Beckwith, J.B.2    Weeks, D.A.3
  • 3
    • 0036203785 scopus 로고    scopus 로고
    • Engraftment and differentiation of human metanephroi into functional mature nephrons after transplantation into mice is accompanied by a profile of gene expression similar to normal human kidney development
    • B. Dekel, N. Amariglio, and N. Kaminski Engraftment and differentiation of human metanephroi into functional mature nephrons after transplantation into mice is accompanied by a profile of gene expression similar to normal human kidney development J Am Soc Nephrol 13 2002 977 990
    • (2002) J Am Soc Nephrol , vol.13 , pp. 977-990
    • Dekel, B.1    Amariglio, N.2    Kaminski, N.3
  • 4
    • 0023568404 scopus 로고
    • Early organogenesis of the kidney
    • L. Saxen, and H. Sariola Early organogenesis of the kidney Pediatr Nephrol 1 1987 385 392
    • (1987) Pediatr Nephrol , vol.1 , pp. 385-392
    • Saxen, L.1    Sariola, H.2
  • 5
    • 33751161268 scopus 로고    scopus 로고
    • The cellular basis of kidney development
    • G.R. Dressler The cellular basis of kidney development Annu Rev Cell Dev Biol 22 2006 509 529
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 509-529
    • Dressler, G.R.1
  • 6
    • 0036151606 scopus 로고    scopus 로고
    • Stem cells in the kidney
    • Q. Al-Awqati, and J.A. Oliver Stem cells in the kidney Kidney Int 61 2002 387 395
    • (2002) Kidney Int , vol.61 , pp. 387-395
    • Al-Awqati, Q.1    Oliver, J.A.2
  • 7
    • 53649093784 scopus 로고    scopus 로고
    • Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
    • S. Metsuyanim, N. Pode-Shakked, and K. Schmidt-Ott Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes Stem Cells 26 2008 1808 1817
    • (2008) Stem Cells , vol.26 , pp. 1808-1817
    • Metsuyanim, S.1    Pode-Shakked, N.2    Schmidt-Ott, K.3
  • 8
    • 0032476037 scopus 로고    scopus 로고
    • Wilms tumor genetics
    • V. Huff Wilms tumor genetics Am J Med Genet 79 1998 260 267
    • (1998) Am J Med Genet , vol.79 , pp. 260-267
    • Huff, V.1
  • 9
    • 83155176084 scopus 로고    scopus 로고
    • Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms tumor onset
    • M. Maschietto, A.P. Trapé, and F.S. Piccoli Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms tumor onset Cell Death Dis 2 2011 e224
    • (2011) Cell Death Dis , vol.2 , pp. 224
    • Maschietto, M.1    Trapé, A.P.2    Piccoli, F.S.3
  • 10
    • 84861203782 scopus 로고    scopus 로고
    • SIX1 protein expression selectively identifies blastemal elements in Wilms tumor
    • D. Sehic, J. Karlsson, and B. Sandstedt SIX1 protein expression selectively identifies blastemal elements in Wilms tumor Pediatr Blood Cancer 59 2012 62 68
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 62-68
    • Sehic, D.1    Karlsson, J.2    Sandstedt, B.3
  • 11
    • 48149095359 scopus 로고    scopus 로고
    • Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
    • A. Kobayashi, M.T. Valerius, and J.W. Mugford Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development Cell Stem Cell 3 2008 169 181
    • (2008) Cell Stem Cell , vol.3 , pp. 169-181
    • Kobayashi, A.1    Valerius, M.T.2    Mugford, J.W.3
  • 12
    • 33750455113 scopus 로고    scopus 로고
    • Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney
    • M. Self, O.V. Lagutin, and B. Bowling Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney EMBO J 25 2006 5214 5228
    • (2006) EMBO J , vol.25 , pp. 5214-5228
    • Self, M.1    Lagutin, O.V.2    Bowling, B.3
  • 13
    • 67650444682 scopus 로고    scopus 로고
    • Cell and molecular biology of kidney development
    • K.J. Reidy, and N.D. Rosenblum Cell and molecular biology of kidney development Semin Nephrol 29 2009 321 337
    • (2009) Semin Nephrol , vol.29 , pp. 321-337
    • Reidy, K.J.1    Rosenblum, N.D.2
  • 14
    • 79960732484 scopus 로고    scopus 로고
    • Kidneys and urinary tract
    • E. Gilbert-Barness, 1st ed. Mosby St. Louis (MO)
    • J. Bernstein, and R.A. Risdon Kidneys and urinary tract E. Gilbert-Barness, 1st ed. Potter's pathology of the fetus and infant Vol. 2 1997 Mosby St. Louis (MO) 875 879
    • (1997) Potter's Pathology of the Fetus and Infant , vol.2 , pp. 875-879
    • Bernstein, J.1    Risdon, R.A.2
  • 15
    • 44049097197 scopus 로고    scopus 로고
    • Six2 and BMP4 mutations associate with anomalous kidney development
    • S. Weber, J.C. Taylor, and P. Winyard Six2 and BMP4 mutations associate with anomalous kidney development J Am Soc Nephrol 19 2008 891 903
    • (2008) J Am Soc Nephrol , vol.19 , pp. 891-903
    • Weber, S.1    Taylor, J.C.2    Winyard, P.3
  • 16
    • 39049186685 scopus 로고    scopus 로고
    • Genetic clonality is a feature unifying nephroblastomas regardless of the variety of morphological subtypes
    • B. Guertl, I. Leuschner, and D. Harms Genetic clonality is a feature unifying nephroblastomas regardless of the variety of morphological subtypes Virchows Arch 449 2006 171 174
    • (2006) Virchows Arch , vol.449 , pp. 171-174
    • Guertl, B.1    Leuschner, I.2    Harms, D.3
  • 18
    • 77955723545 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis
    • F. Balaguer, A. Link, and J.J. Lozano Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis Cancer Res 70 2010 6609 6618
    • (2010) Cancer Res , vol.70 , pp. 6609-6618
    • Balaguer, F.1    Link, A.2    Lozano, J.J.3
  • 19
    • 35648943189 scopus 로고    scopus 로고
    • A Hox-Eya-Pax complex regulates early kidney developmental gene expression
    • K.Q. Gong, A.R. Yallowitz, and H. Sun A Hox-Eya-Pax complex regulates early kidney developmental gene expression Mol Cell Biol 27 2007 7661 7668
    • (2007) Mol Cell Biol , vol.27 , pp. 7661-7668
    • Gong, K.Q.1    Yallowitz, A.R.2    Sun, H.3
  • 20
    • 41449103606 scopus 로고    scopus 로고
    • Stem cells in the embryonic kidney
    • R. Nishinkamura Stem cells in the embryonic kidney Kidney Int 73 2008 913 917
    • (2008) Kidney Int , vol.73 , pp. 913-917
    • Nishinkamura, R.1
  • 21
    • 22944463010 scopus 로고    scopus 로고
    • Wnt9b plays a central role in the regulation of in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system
    • T.J. Carroll, J.S. Park, and S. Hayashi Wnt9b plays a central role in the regulation of in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system Dev Cell 9 2005 283 292
    • (2005) Dev Cell , vol.9 , pp. 283-292
    • Carroll, T.J.1    Park, J.S.2    Hayashi, S.3
  • 22
    • 61349113324 scopus 로고    scopus 로고
    • Canonical WNT signalling determines lineage specificity in Wilms Tumour
    • R. Fuzukawa, M.R. Anaka, and R.J. Weeks Canonical WNT signalling determines lineage specificity in Wilms Tumour Oncogene 28 2009 1063 1075
    • (2009) Oncogene , vol.28 , pp. 1063-1075
    • Fuzukawa, R.1    Anaka, M.R.2    Weeks, R.J.3
  • 23
    • 77950641105 scopus 로고    scopus 로고
    • Children's Cancer and Leukaemia Group; SIOP Wilms' Tumour Biology Group. Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilm's tumor
    • R.D. Williams, R. Al-Saadi, and T. Chagtai Children's Cancer and Leukaemia Group; SIOP Wilms' Tumour Biology Group. Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilm's tumor Clin Cancer Res 16 2010 2036 2045
    • (2010) Clin Cancer Res , vol.16 , pp. 2036-2045
    • Williams, R.D.1    Al-Saadi, R.2    Chagtai, T.3
  • 24
    • 72549092942 scopus 로고    scopus 로고
    • Subsets of very low risk Wilms tumor show distinctive gene expression, histologic and clinical features
    • S.T. Sredni, S. Gadd, and C.C. Huang Subsets of very low risk Wilms tumor show distinctive gene expression, histologic and clinical features Clin Cancer Res 15 2009 6800 6809
    • (2009) Clin Cancer Res , vol.15 , pp. 6800-6809
    • Sredni, S.T.1    Gadd, S.2    Huang, C.C.3
  • 25
    • 51249117310 scopus 로고    scopus 로고
    • Molecular profiling of isolated histological components of Wilms tumor implicates a common role for the Wnt signaling pathway in kidney and tumor development
    • M. Maschietto, B. deCamargo, and H. Brentani Molecular profiling of isolated histological components of Wilms tumor implicates a common role for the Wnt signaling pathway in kidney and tumor development Oncology 75 2008 81 91
    • (2008) Oncology , vol.75 , pp. 81-91
    • Maschietto, M.1    Decamargo, B.2    Brentani, H.3
  • 26
    • 0036087979 scopus 로고    scopus 로고
    • Gene expression in Wilms tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition
    • C. Li, M. Guo, and A. Borczuk Gene expression in Wilms tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition Am J Pathol 160 2002 2181 2190
    • (2002) Am J Pathol , vol.160 , pp. 2181-2190
    • Li, C.1    Guo, M.2    Borczuk, A.3
  • 27
    • 72949107385 scopus 로고    scopus 로고
    • Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population
    • N. Pode-Shakked, S. Metsuyanim, and E. Rom-Gross Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population J Cell Mol Med 13 2009 1792 1808
    • (2009) J Cell Mol Med , vol.13 , pp. 1792-1808
    • Pode-Shakked, N.1    Metsuyanim, S.2    Rom-Gross, E.3
  • 28
    • 0035073085 scopus 로고    scopus 로고
    • Clinical impact of histologic subtypes in localized non-anaplastic nephroblastoma treated according to the trial and study SIOP-9/GPOH
    • A. Weirich, I. Leuschner, and D. Harms Clinical impact of histologic subtypes in localized non-anaplastic nephroblastoma treated according to the trial and study SIOP-9/GPOH Ann Oncol 12 2009 311 319
    • (2009) Ann Oncol , vol.12 , pp. 311-319
    • Weirich, A.1    Leuschner, I.2    Harms, D.3
  • 29
    • 79960708293 scopus 로고    scopus 로고
    • Lim1, an embryonal transcription factor, is absent in multicystic renal dysplasia, but reactivated in nephroblastomas
    • B. Guertl, U. Senanayake, and E. Nusshold Lim1, an embryonal transcription factor, is absent in multicystic renal dysplasia, but reactivated in nephroblastomas Pathobiology 78 2011 210 219
    • (2011) Pathobiology , vol.78 , pp. 210-219
    • Guertl, B.1    Senanayake, U.2    Nusshold, E.3
  • 30
    • 34250014480 scopus 로고    scopus 로고
    • Expression profiles of congenital renal dysplasia reveal new insights into renal development and disease
    • S. Jain, A.A. Suarez, and J. McGuire Expression profiles of congenital renal dysplasia reveal new insights into renal development and disease Pediatr Nephrol 22 2007 962 974
    • (2007) Pediatr Nephrol , vol.22 , pp. 962-974
    • Jain, S.1    Suarez, A.A.2    McGuire, J.3
  • 31
    • 0029838116 scopus 로고    scopus 로고
    • Pax-2, kidney development and oncogenesis
    • G.R. Dressler Pax-2, kidney development and oncogenesis Med Pediatr Oncol 27 1996 440 444
    • (1996) Med Pediatr Oncol , vol.27 , pp. 440-444
    • Dressler, G.R.1
  • 32
    • 0036918019 scopus 로고    scopus 로고
    • Genetic progression of renal cell carcinoma
    • H. Moch, and M.J. Mihatsch Genetic progression of renal cell carcinoma Virchows Arch 441 2002 320 327
    • (2002) Virchows Arch , vol.441 , pp. 320-327
    • Moch, H.1    Mihatsch, M.J.2
  • 33
    • 65549085564 scopus 로고    scopus 로고
    • Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics
    • C.L. DaSilva, R. Goncalves, and C.D. Porada Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics J Cell Physiol 220 2009 102 111
    • (2009) J Cell Physiol , vol.220 , pp. 102-111
    • Dasilva, C.L.1    Goncalves, R.2    Porada, C.D.3
  • 34
    • 0030933062 scopus 로고    scopus 로고
    • Regulatory mechanisms in stem cell biology
    • S.J. Morrison, N.M. Shah, and D.J. Anderson Regulatory mechanisms in stem cell biology Cell 88 1997 287 298
    • (1997) Cell , vol.88 , pp. 287-298
    • Morrison, S.J.1    Shah, N.M.2    Anderson, D.J.3
  • 35
    • 79954610144 scopus 로고    scopus 로고
    • Lim-class homeobox gene Lim1, a novel oncogene in human renal cell carcinoma
    • V. Dormoy, C. Beraud, and V. Lindner Lim-class homeobox gene Lim1, a novel oncogene in human renal cell carcinoma Oncogene 30 2010 1753 1763
    • (2010) Oncogene , vol.30 , pp. 1753-1763
    • Dormoy, V.1    Beraud, C.2    Lindner, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.