Biomarkers of myocardial ischemia in the emergency room: Cardiospecific troponin and beyond

European Journal of Internal Medicine

Volumn 24, Issue 2, 2013, Pages 97-99

  Lippi, Giuseppe ^a  

^a Academic Hospital of Parma   (Italy)

Author keywords

Copeptin; Ischemic heart disease; Myocardial infarction; Troponin

Indexed keywords

BIOLOGICAL MARKER; TROPONIN;

ACUTE CORONARY SYNDROME; COST BENEFIT ANALYSIS; DIAGNOSTIC TEST; EMERGENCY WARD; GOLD STANDARD; HEART MUSCLE ISCHEMIA; HUMAN; REVIEW; THORAX PAIN;

BIOLOGICAL MARKERS; DIAGNOSIS, DIFFERENTIAL; EMERGENCY SERVICE, HOSPITAL; HUMANS; MYOCARDIAL ISCHEMIA; SEVERITY OF ILLNESS INDEX; TROPONIN;

EID: 84873727501     PISSN: 09536205     EISSN: 18790828     Source Type: Journal    
DOI: 10.1016/j.ejim.2012.10.012     Document Type: Review

References (21)

1. V.L. Roger, A.S. Go, D.M. Lloyd-Jones, E.J. Benjamin, J.D. Berry, and W.B. Borden American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Executive summary: heart disease and stroke statistics - 2012 update: a report from the American Heart Association Circulation 125 2012 188 197
2. M.L. McCarthy Overcrowding in emergency departments and adverse outcomes BMJ 342 2011 d2830
3. G. Lippi, G. Cervellin, and M. Plebani Sensitive cardiac troponin T assay N Engl J Med 362 2010 1242
4. F.S. Apple, R. Ler, and M.M. Murakami Determination of 19 cardiac troponin I and T Assay 99th percentile values from a common presumably healthy population Clin Chem 58 2012 1574 1581
5. K. Thygesen, J. Mair, E. Giannitsis, C. Mueller, B. Lindahl, and S. Blankenberg The study group on biomarkers in cardiology of the ESC working group on acute cardiac care. How to use high-sensitivity cardiac troponins in acute cardiac care Eur Heart J 33 2012 2252 2257
6. G. Lippi, M. Montagnana, R. Aloe, and G. Cervellin Highly sensitive troponin immunoassays: navigating between the scylla and charybdis Adv Clin Chem 58 2012 1 29
7. G. Lippi, and G. Cervellin Identification of troponin determinants for improving its diagnostic performance in the emergency department J Emerg Med 2012 [Epub ahead of print]
8. G. Lippi, M. Montagnana, G.L. Salvagno, and G.C. Guidi Potential value for new diagnostic markers in the early recognition of acute coronary syndromes CJEM 8 2006 27 31
9. G. Lippi, M. Plebani, S. Di Somma, V. Monzani, M. Tubaro, and M. Volpe Considerations for early acute myocardial infarction rule-out for emergency department chest pain patients: the case of copeptin Clin Chem Lab Med 50 2012 243 253
10. M. Montagnana, G. Lippi, E. Danese, G.L. Salvagno, G. Cervellin, and G.C. Guidi Serum concentration of neopterin on admission does not improve the diagnostic performance of highly-sensitive troponin I Clin Chem Lab Med 50 2012 747 748
11. M. Montagnana, G. Cervellin, T. Meschi, and G. Lippi The role of red blood cell distribution width in cardiovascular and thrombotic disorders Clin Chem Lab Med 50 2011 635 641
12. G. Lippi, G. Cervellin, and G. Targher Random plasma glucose measurement may improve the diagnostic specificity of highly sensitive troponin in the emergency department Int J Cardiol 155 2012 172 173
13. G. Lippi, R. Aloe, and G. Cervellin p2PSA but not total and free PSA increases after myocardial infarction: results of a preliminary investigation Int J Cardiol 153 2011 119
14. C. Folli, D. Consonni, M. Spessot, L. Salvini, M. Velati, and G. Ranzani Diagnostic role of copeptin in patients presenting with chest pain in the emergency room Eur J Intern Med 2012 10.1016/j.ejim.2012.09.006 [Epub ahead of print]
15. E. Giannitsis, K. Kurz, K. Hallermayer, J. Jarausch, A.S. Jaffe, and H.A. Katus Analytical validation of a high-sensitivity cardiac troponin T assay Clin Chem 56 2010 254 261
16. B. Lindahl, P. Venge, and S. James The new high-sensitivity cardiac troponin T assay improves risk assessment in acute coronary syndromes Am Heart J 160 2010 224 229
17. S.J. Aldous, C.M. Florkowski, I.G. Crozier, P. George, R. Mackay, and M. Than High sensitivity troponin outperforms contemporary assays in predicting major adverse cardiac events up to two years in patients with chest pain Ann Clin Biochem 48 2011 249 255
18. G. Lippi, and G.C. Guidi The power of negative thinking Am J Emerg Med 26 2008 373 374
19. G. Lippi, C. Mattiuzzi, and G. Cervellin Circulating microRNAs (miRs) for diagnosing acute myocardial infarction: meta-analysis of available studies Int J Cardiol 2012 10.1016/j.ijcard.2012.09.152 [Epub ahead of print]
20. Biomarkers Definitions Working Group Biomarkers and surrogate endpoints: preferred definitions and conceptual framework Clin Pharmacol Ther 69 2001 89 95
21. G. Lippi, L. Teti, M. Dipalo, and G. Cervellin Relationship between red blood cell distribution width and prognostic biomarkers in patients admitted to the emergency department with acute infections Eur J Intern Med 2012 10.1016/j.ejim.2012.09.005 [pii: S0953-6205(12)00243-9, [Epub ahead of print]]