Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 7, 2013, Pages 2452-2459

  Basan, Markus ^a   Elgeti, Jens ^b   Hannezo, Edouard ^c   Rappel, Wouter Jan ^a   Levine, Herbert ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c CNRS   (France)

^d Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DEATH; CELL DENSITY; CELL DIVISION; CELL MOTILITY; CELL POLARITY; CELL SIZE; CELL SPREADING; CELL VOLUME; IN VIVO STUDY; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SIMULATION; TENSILE STRENGTH; VELOCITY; WOUND HEALING;

CELL MOVEMENT; COMPUTER SIMULATION; EPITHELIAL CELLS; MODELS, BIOLOGICAL; STRESS, MECHANICAL; WOUND HEALING;

EID: 84873721320     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1219937110     Document Type: Article

References (38)

1. Nguyen D, Orgill D, Murphy G (2009 The pathophysiologic basis for wound healing and cutaneous regeneration. Biomaterials for Treating Skin Loss, eds Orgill DP, Blanco C (Woodhead Publishing, UK; CRC Press, Cambridge, UK/Boca Raton, FL), pp 25-57
2. Stadelmann WK, Digenis AG, Tobin GR (1998 Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 176(2A, Suppl):26S-38S.
3. Santoro MM, Gaudino G (2005) Cellular and molecular facets of keratinocyte reepithelization during wound healing. Exp Cell Res 304(1):274-286. (Pubitemid 40222094)
4. Poujade M, et al. (2007) Collective migration of an epithelial monolayer in response to a model wound. Proc Natl Acad Sci USA 104(41):15988-15993. (Pubitemid 350099346)
5. Mark S, et al. (2010 Physical model of the dynamic instability in an expanding cell culture. Biophys J 98(3):361-370
6. Reffay M, et al. (2011 Orientation and polarity in collectively migrating cell structures: Statics and dynamics. Biophys J 100(11):2566-2575
7. Petitjean L, et al. (2010 Velocity fi elds in a collectively migrating epithelium. Biophys J 98(9):1790-1800
8. Angelini TE, Hannezo E, Trepat X, Fredberg JJ, Weitz DA (2010 Cell migration driven by cooperative substrate deformation patterns. Phys Rev Lett 104(16):168104-168108
9. Angelini TE, et al. (2011 Glass-like dynamics of collective cell migration. Proc Natl Acad Sci USA 108(12):4714-4719
10. du Roure O, et al. (2005 Force mapping in epithelial cell migration. Proc Natl Acad Sci USA 102(7):2390-2395
11. Trepat X, et al. (2009 Physical forces during collective cell migration. Nat Phys 5(6):426-430
12. Gov NS (2009 Traction forces during collective cell motion. HFSP J 3(4):223-227
13. Lee P, Wolgemuth CW(2011 Crawling cells can close wounds without purse strings or signaling. PLOS Comput Biol 7(3):e1002007.
14. Lee P, Wolgemuth C (2011 Advent of complex flows in epithelial tissues. Phys Rev E Stat Nonlin Soft Matter Phys 83(6 Pt 1):061920-061925
15. Puliafito A, et al. (2012 Collective and single cell behavior in epithelial contact inhibition. Proc Natl Acad Sci USA 109(3):739-744
16. Serra-Picamal X, et al. (2012 Mechanical waves during tissue expansion. Nat Phys 8(8):628-634
17. Henkes S, Fily Y, Marchetti MC (2011 Active jamming: Self-propelled soft particles at high density. Phys Rev E Stat Nonlin Soft Matter Phys 84(4 Pt 1):040301-040305
18. Vicsek T, Czirók A, Ben-Jacob E, Cohen I, Shochet O (1995 Novel type of phase transition in a system of self-driven particles. Phys Rev Lett 75(6):1226-1229
19. Szabó B, et al. (2006 Phase transition in the collective migration of tissue cells: Experiment and model. Phys Rev E Stat Nonlin Soft Matter Phys 74(6 Pt 1):061908-061913
20. Drasdo D, Kree R, McCaskill JS (1995 Monte Carlo approach to tissue-cell populations. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 52(6):6635-6657
21. Galle J, Loeffler M, Drasdo D (2005) Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro. Biophys J 88(1):62-75. (Pubitemid 40070658)
22. Farooqui R, Fenteany G (2005) Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement. J Cell Sci 118(Pt 1):51-63. (Pubitemid 40277104)
23. Aznavoorian S, Stracke ML, Krutzsch H, Schiffmann E, Liotta LA (1990 Signal transduction for chemotaxis and haptotaxis by matrix molecules in tumor cells. J Cell Biol 110(4):1427-1438
24. Schwarz US, Bischofs IB (2005) Physical determinants of cell organization in soft media. Med Eng Phys 27(9):763-772. (Pubitemid 41318124)
25. Saez A, et al. (2010 Traction forces exerted by epithelial cell sheets. J Phys Condens Matter 22(19):194119-194128
26. Czirók A, Vicsek M, Vicsek T (1999 Collective motion of organisms in three dimensions. Phys A Stat Theor Phys 264(1-2):299-304
27. Toner J, Tu Y (1998) Flocks, herds, and schools: A quantitative theory of flocking. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 58(4):4828-4858. (Pubitemid 128596420)
28. Rappel W-J, Nicol A, Sarkissian A, Levine H, Loomis W (1999) Self-organized vortex state in two-dimensional dictyostelium dynamics. Phys Rev Lett 83(6):1247-1250. (Pubitemid 129689757)
29. Basan M, Prost J, Joanny JF, Elgeti J (2011 Dissipative particle dynamics simulations for biological tissues: Rheology and competition. Phys Biol 8(2):026014-026027
30. Ranft J, et al. (2010 Fluidization of tissues by cell division and apoptosis. Proc Natl Acad Sci USA 107(49):20863-20868
31. Montel F, et al. (2011 Stress clamp experiments on multicellular tumor spheroids. Phys Rev Lett 107(18):188102-188106
32. Nikunen P, Karttunen M, Vattulainen I (2003 How would you integrate the equations of motion in dissipative particle dynamics simulations? Comput Phys Commun 153(3):407-423
33. Tambe DT, et al. (2011 Collective cell guidance by cooperative intercellular forces. Nat Mater 10(6):469-475
34. Zaritsky A, Natan S, Ben-Jacob E, Tsarfaty I (2012 Emergence of HGF/SF-induced coordinated cellular motility. PLoS ONE 7(9):e44671.
35. Basan M, Risler T, Joanny JF, Sastre-Garau X, Prost J (2009 Homeostatic competition drives tumor growth and metastasis nucleation. HFSP J 3(4):265-272
36. Drees F, Pokutta S, Yamada S, Nelson WJ, Weis WI (2005) α-Catenin is a molecular switch that binds E-cadherin-β-catenin and regulates actin-filament assembly. Cell 123(5):903-915. (Pubitemid 41721035)
37. Basan M, Idema T, Lenz M, Joanny JF, Risler T (2010 A reaction-diffusion model of the cadherin-catenin system: A possible mechanism for contact inhibition and implications for tumorigenesis. Biophys J 98(12):2770-2779
38. Zaidel-Bar R, Kam Z, Geiger B (2005) Polarized downregulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow. J Cell Sci 118(Pt 17):3997-4007. (Pubitemid 41410282)