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19920051 10.1056/NEJMoa0909938 1:CAS:528:DC%2BD1MXhsFWgs7%2FE Landmark trial demonstrating clearly superior survival and durability of a continous flow LVAD (Heartmate II) compared to the previous destination LVAD
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22619284 10.1161/CIRCULATIONAHA.111.058412 This multi-center, prospective trial established the HeartWare HVAD in bridge to transplant patients and demonstrated excellent outcomes with over 90 % of patients being alive on device support or transplanted by 6 months
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20413033 10.1016/j.jacc.2009.12.052 This was an important work in that it is the largest and most thorough examination of the impact of continuous flow LVADs on quality of life and functional capacity. It demonstrated marked and durable improvements in essentially every measure
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• Rogers JG, Aaronson KD, Boyle AJ, et al. Continuous flow left ventricular assist device improves functional capacity and quality of life of advanced heart failure patients. J Am Coll Cardiol. 2010;55:1826-34. This was an important work in that it is the largest and most thorough examination of the impact of continuous flow LVADs on quality of life and functional capacity. It demonstrated marked and durable improvements in essentially every measure.
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22052901 10.1161/CIRCHEARTFAILURE.111.962951 This paper is important as it showed the drastically improving cost-effectiveness of LVADs as destination therapy
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• Rogers JG, Bostic RR, Tong KB, Adamson R, Russo M, Slaughter MS. Cost-effectiveness analysis of continuous-flow left ventricular assist devices as destination therapy. Circ Heart Fail. 2012;5:10-6. This paper is important as it showed the drastically improving cost-effectiveness of LVADs as destination therapy.
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