Association of cardiovascular and metabolic disease genes with psoriasis

Journal of Investigative Dermatology

Volumn 133, Issue 3, 2013, Pages 836-839

  Lu, Yingchang ^a   Chen, Haoyan ^a   Nikamo, Pernilla ^b   Low, Hui Qi ^c   Helms, Cynthia ^d   Seielstad, Mark ^a,c   Liu, Jianjun ^c   Bowcock, Anne M ^d   Stahle, Mona ^b   Liao, Wilson ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c GENOME INSTITUTE OF SINGAPORE   (Singapore)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY MASS; CARDIOVASCULAR DISEASE; COMORBIDITY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LETTER; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PSORIASIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84873718034     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.366     Document Type: Letter

References (18)

1. Carlsson B, Kindberg E, Buesa J et al. (2009) The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection. PLoS One 4: e5593
2. Chen H, Hayashi G, Lai OY et al. (2012) Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease. Plos Genet 8: e1002514
3. Chen H, Poon A, Yeung C et al. (2011) A genetic risk score combining ten psoriasis risk loci improves disease prediction. PLoS One 6: e19454
4. Davidovici BB, Sattar N, Prinz JC et al. (2010) Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. J Invest Dermatol 130: 1785-96
5. Devalliere J, Charreau B (2011) The adaptor Lnk (SH2B3): an emerging regulator in vascular cells and a link between immune and inflammatory signaling. Biochem Pharmacol 82: 1391-402
6. Ellinghaus D, Ellinghaus E, Nair RP et al. (2012) Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. Am J Hum Genet 90: 636-47
7. Folseraas T, Melum E, Rausch P et al. (2012) Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci. J Hepatol 57: 366-75
8. Fransen K, Visschedijk MC, van Sommeren S et al. (2010) Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. Hum Mol Genet 19: 3482-8
9. Jin Y, Birlea SA, Fain PR et al. (2012) Genomewide association analyses identify 13 new susceptibility loci for generalized vitiligo. Nat Genet 44: 676-80
10. Liu Y, Helms C, Liao W et al. (2008) A genomewide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet 4: e1000041
11. McCarthy MI (2010) Genomics, type 2 diabetes, and obesity. N Engl J Med 363: 2339-50
12. Nair RP, Duffin KC, Helms C et al. (2009) Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet 41: 199-204
13. O'Donnell CJ, Nabel EG (2011) Genomics of cardiovascular disease. N Engl J Med 365: 2098-109
14. Peden JF, Farrall M (2011) Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour. Hum Mol Genet 20: R198-205
15. Smyth DJ, Cooper JD, Howson JM et al. (2011) FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection. Diabetes 60: 3081-4
16. Strange A, Capon F, Spencer CC et al. (2010) A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 42: 985-90
17. Wang S, Adrianto I, Wiley GB et al. (2012) A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun 13: 380-7
18. Zhernakova A, Stahl EA, Trynka G et al. (2011) Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet 7: e1002004