Maternal high-fat diet impacts endothelial function in nonhuman primate offspring

International Journal of Obesity

Volumn 37, Issue 2, 2013, Pages 254-262

  Fan, L ^a,b   Lindsley, S R ^a   Comstock, S M ^a   Takahashi, D L ^a   Evans, A E ^a   He, G W ^b   Thornburg, K L ^c   Grove, K L ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Cardiovascular Research Laboratory   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

endothelium; intrauterine; juvenile offspring; over nutrition; programming

Indexed keywords

ACETYLCHOLINE; INSULIN;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENVIRONMENTAL EXPOSURE; FEMALE; INSULIN BLOOD LEVEL; INSULIN RELEASE; LIPID DIET; NONHUMAN; PERINATAL PERIOD; PREGNANCY; PRIORITY JOURNAL; PROGENY; VASODILATATION;

ANIMALS; ANIMALS, NEWBORN; CAROTID INTIMA-MEDIA THICKNESS; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; FASTING; FEMALE; FETAL GROWTH RETARDATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIVER; MACACA; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MATERNAL-FETAL EXCHANGE; OBESITY; OVERNUTRITION; PLACENTAL INSUFFICIENCY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PRIMATES; REAL-TIME POLYMERASE CHAIN REACTION; WEANING;

ANIMALIA; PRIMATES;

EID: 84873717164     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2012.42     Document Type: Article

References (51)

1. Han JC, Lawlor DA, Kimm SY. Childhood obesity. Lancet 2010; 375: 1737-1748.
2. Barker DJ, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. Lancet 1993; 341: 938-941.
3. Barker DJ. Fetal origins of cardiovascular disease. Ann Med 1999; 31 (Suppl 1): 3-6.
4. Barker DJ. Fetal programming of coronary heart disease. Trends Endocrinol Metab 2002; 13: 364-368.
5. Strauss RS. Effects of the intrauterine environment on childhood growth. Br Med Bull 1997; 53: 81-95.
6. Ravelli AC, Der Meulen JH, Osmond C, Barker DJ, Bleker OP. Obesity at the age of 50 y in men and women exposed to famine prenatally. Am J Clin Nutr 1999; 70: 811-816.
7. McMillen IC, Robunson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 2005; 85: 571-633.
8. Le Clair C, Abbi T, Sandhu H, Tappia PS. Impact of maternal undernutrition on diabetes and cardiovascular disease risk in adult offspring. Can J Physiol Pharmacol 2009; 87: 161-179.
9. Vonnahme KA, Hess BW, Hansen TR, McCormick RJ, Rule DC, Moss GE et al. Maternal undernutrition from early-to mid-gestation leads to growth retardation, cardiac ventricular hypertrophy, and increased liver weight in the fetal sheep. Biol Reprod 2003; 69: 133-140.
10. Gopalakrishnan GS, Gardner DS, Dandrea J, Langley-Evans SC, Pearce S, Kurlak LO et al. Influence of maternal pre-pregnancy body composition and diet during early-mid pregnancy on cardiovascular function and nephron number in juvenile sheep. Br J Nutr 2005; 94: 938-947.
11. Morrison JL, Botting KJ, Dyer JL, Williams SJ, Thornburg KL, McMillen IC. Restriction of placental function alters heart development in the sheep fetus. Am J Physiol Regul Integr Comp Physiol 2007; 293: R306-R313.
12. Louey S, Jonker SS, Giraud GD, Thornburg KL. Placental insufficiency decreases cell cycle activity and terminal maturation in fetal sheep cardiomyocytes. J Physiol 2007; 580 (Part 2): 639-648.
13. Armitage JA, Lakasing L, Taylor PD, Balachandran AA, Jensen RI, Dekon V et al. Developmental programming of aortic and renal structure in offspring of rats fed fat-rich diets in pregnancy. J Physiol 2005; 565: 171-184.
14. Taylor PD, McConnell J, Khan IY, Holemans K, Lawrence KM, Asare-Anane H et al. Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy. Am J Physiol Regul Integr Comp Physiol 2005; 288: R134-R139.
15. Samuelsson AM, Matthews PA, Argenton M, Christie MR, McConnell JM, Jansen EH et al. Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programming. Hypertension 2008; 51: 383-392.
16. McCurdy CE, Bishop JM, Williams SM, Grayson BE, Smith SM, Friedman JE et al. Maternal high fat diet triggers lipotoxicity in the fetal liver of the nonhuman primate. J Clin Invest 2009; 19: 323-335.
17. Frias AE, Morgan TK, Evans AE, Rasanen J, Oh KY, Thornburg KL et al. Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillbirth in a Nonhuman Primate model of excess nutrition. Endocrinology 2011; 152: 2456-2464.
18. Sullivan EL, Grayson B, Takahashi D, Robertson N, Maier A, Bethea CL et al. Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring. J Neurosci 2010; 30: 3826-3830.
19. Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL. Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet. Endocrinology 2010; 151: 1622-1632.
20. Suter M, Bocock P, Showalter L, Hu M, Shope C, McKnight R et al. Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates. FASEB J 2011; 25: 714-726.
21. Cox J, Williams S, Grove KL, Lane RH, Aagaard-Tillery KM. A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome. Am J Obstet Gynecol 2009; 201: 281.e1-9.
22. Meyers MR, Gokce N. Endothelial dysfunction in obesity: etiological role in atherosclerosis. Curr Opin Endocrinol Diabetes Obes 2007; 14: 365-369.
23. Poirier P, Eckel RH. Obesity and cardiovascular disease. Curr Atheroscler Rep 2002; 4: 448-453.
24. Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006; 113: 898-918.
25. Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 2004; 109: III27-III32.
26. Lerman A, Zeiher AM. Endothelial function: cardiac events. Circulation 2005; 111: 363-368.
27. Stepp DW. Impact of obesity and insulin resistance on vasomotor tone: nitric oxide and beyond. Clin Exp Pharmacol Physiol 2006; 33: 407-414.
28. Tabit CE, Chung WB, Hamburg NM, Vita JA. Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord 2010; 11: 61-74.
29. Bakker W, Eringa EC, Sipkema P, van Hinsbergh VW. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res 2009; 335: 165-189.
30. Calles-Escandon J, Cipolla M. Diabetes and endothelial dysfunction: a clinical perspective. Endocr Rev 2001; 22: 36-52.
31. Meyers MR, Gokce N. Endothelial dysfunction in obesity: etiological role in atherosclerosis. Curr Opin Endocrinol Diabetes Obes 2007; 14: 365-369.
32. Damjanovic M, Barton M. Food intake and cardiovascular response. Curr Hypertens Rep 2008; 10: 25-31.
33. Solnica B, Naskalski JW. Quality of SMBG in clinical practice. Scand J Clin Lab Invest Suppl 2005; 240: 80-85.
34. Fan L, Yang Q, Xiao XQ, Grove KL, Huang Y, Chen ZW et al. Dual actions of cilnidipine in human internal thoracic artery: inhibition of calcium channels and enhancement of endothelial nitric oxide synthase. J Thorac Cardiovasc Surg 2011; 141: 1063-1069.
35. He GW, Fan L, Furnary A, Yang Q. A new antispastic solution for arterial grafting: nicardipine and nitroglycerin cocktail in preparation of internal thoracic and radial arteries for coronary surgery. J Thorac Cardiovasc Surg 2008; 136: 673-680, 680.e1-2.
36. Kakafika AI, Liberopoulos EN, Karagiannis A, Athyros VG, Mikhailidis DP. Dyslipidaemia, hypercoagulability and the metabolic syndrome. Curr Vasc Pharmacol 2006; 4: 175-183.
37. Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006; 444: 875-880.
38. Yoshida M, Tomiyama H, Yamada J, Matsumoto C, Odaira M, Shiina K et al. Relationship of insulin resistance to macro-and microvasculature reactivity in hypertension. Am J Hypert 2010; 23: 495-500.
39. Shimokawa H. Primary endothelial dysfunction: atherosclerosis. J Mol Cell Cardio 1999; 31: 23-37.
40. Cynober LA. Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance. Nutrition 2002; 18: 761-766.
41. Pollock JS, Fö rstermann U, Mitchell JA, Warner TD, Schmidt HH, Nakane M et al. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci USA 1991; 88: 10480-10484.
42. Luscher TF, Vanhoutte PM. The Endothelium: Modulator of Cardiovascular Function. CRC Press Inc.: Boca Raton, FL, USA, 1990.
43. Naseem KM. The role of nitric oxide in cardiovascular diseases. Mol Aspects Med 2005; 26: 33-65.
44. Tanner FC, Meier P, Greutert H, Champion C, Nabel EG, Luscher TF. Nitric oxide modulates expression of cell cycle regulatory proteins: a cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation. Circulation 2000; 101: 1982-1989.
45. Tedgui A, Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 2006; 86: 515-581.
46. Braunersreuther V, Mach F, Steffens S. The specific role of chemokines in atherosclerosis. Thromb Haemost 2007; 97: 714-721.
47. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340: 115-126.
48. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002; 105: 1135-1143.
49. Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006; 113: 1888-1904.
50. Wheatcroft SB, Williams IL, Shah AM, Kearney MT. Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet Med 2003; 20: 255-268.
51. Kearney MT, Duncan ER, Kahn M, Wheatcroft SB. Insulin resistance and endothelial cell dysfunction: studies in mammaliam models. Exp Physiol 2007; 93: 158-163.