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Volumn 13, Issue 1, 2013, Pages 75-80

Antiproliferative in vitro effects of BI 2536-mediated PLK1 inhibition on cervical adenocarcinoma cells

Author keywords

Apoptosis; BI 2536; Cervical carcinoma; Mitotic arrest

Indexed keywords

4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE; CASPASE 3; POLO LIKE KINASE 1;

EID: 84873715461     PISSN: 15918890     EISSN: 15919528     Source Type: Journal    
DOI: 10.1007/s10238-011-0166-1     Document Type: Article
Times cited : (10)

References (12)
  • 1
    • 77958176133 scopus 로고    scopus 로고
    • Cervical tumors
    • 20974359 10.1053/j.sult.2010.07.004
    • Sahdev A (2010) Cervical tumors. Semin Ultrasound CT MR 31:399-413
    • (2010) Semin Ultrasound CT MR , vol.31 , pp. 399-413
    • Sahdev, A.1
  • 2
    • 13244253709 scopus 로고    scopus 로고
    • Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues
    • 15640841 10.1038/sj.onc.1208219 1:CAS:528:DC%2BD2MXhvVKitA%3D%3D
    • Winkles JA, Alberts GF (2005) Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues. Oncogene 24:260-266
    • (2005) Oncogene , vol.24 , pp. 260-266
    • Winkles, J.A.1    Alberts, G.F.2
  • 3
    • 77954989991 scopus 로고    scopus 로고
    • Expression profiling of G2/M phase regulatory proteins in normal, premalignant and malignant uterine cervix and their correlation with survival of patients
    • 20622363 10.4103/0973-1482.65242
    • Saxena M, Singh S, Negi MP, Srivastava AK, Trivedi R, Singh U, Pant MC, Bhatt ML (2010) Expression profiling of G2/M phase regulatory proteins in normal, premalignant and malignant uterine cervix and their correlation with survival of patients. J Cancer Res Ther 6:167-171
    • (2010) J Cancer Res Ther , vol.6 , pp. 167-171
    • Saxena, M.1    Singh, S.2    Negi, M.P.3    Srivastava, A.K.4    Trivedi, R.5    Singh, U.6    Pant, M.C.7    Bhatt, M.L.8
  • 4
    • 0037132736 scopus 로고    scopus 로고
    • Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
    • 12488480 10.1093/jnci/94.24.1863 1:CAS:528:DC%2BD3sXlsFyisg%3D%3D
    • Spankuch-Schmitt B, Bereiter-Hahn J, Kaufmann M, Strebhardt K (2002) Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells. J Natl Cancer Inst 94:1863-1877
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1863-1877
    • Spankuch-Schmitt, B.1    Bereiter-Hahn, J.2    Kaufmann, M.3    Strebhardt, K.4
  • 6
    • 79956044137 scopus 로고    scopus 로고
    • Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells
    • 19554017 10.1038/jid.2009.172 1:CAS:528:DC%2BD1MXhtl2jsLrE
    • Schmit TL, Zhong W, Setaluri V, Spiegelman VS, Ahmad N (2009) Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells. J Invest Dermatol 129:2843-2853
    • (2009) J Invest Dermatol , vol.129 , pp. 2843-2853
    • Schmit, T.L.1    Zhong, W.2    Setaluri, V.3    Spiegelman, V.S.4    Ahmad, N.5
  • 7
    • 0031578244 scopus 로고    scopus 로고
    • Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase
    • 9177283 10.1006/bbrc.1997.6633 1:CAS:528:DyaK2sXjsFCitLo%3D
    • Smith MR, Wilson ML, Hamanaka R, Chase D, Kung H, Longo DL, Ferris DK (1997) Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase. Biochem Biophys Res Commun 234:397-405
    • (1997) Biochem Biophys Res Commun , vol.234 , pp. 397-405
    • Smith, M.R.1    Wilson, M.L.2    Hamanaka, R.3    Chase, D.4    Kung, H.5    Longo, D.L.6    Ferris, D.K.7
  • 8
    • 77958574408 scopus 로고    scopus 로고
    • The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro
    • 20886032 10.1371/journal.pone.0012963
    • Lu B, Mahmud H, Maass AH, Yu B, van Gilst WH, de Boer RA, Silljé HH (2010) The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro. PLoS One 5:e12963
    • (2010) PLoS One , vol.5 , pp. 12963
    • Lu, B.1    Mahmud, H.2    Maass, A.H.3    Yu, B.4    Van Gilst, W.H.5    De Boer, R.A.6    Silljé, H.H.7
  • 9
    • 33748579014 scopus 로고    scopus 로고
    • Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells
    • 16927022 10.1007/s10495-006-9421-4 1:CAS:528:DC%2BD28XptF2rurY%3D
    • Gao Q, Huang X, Tang D, Cao Y, Chen G, Lu Y, Zhuang L, Wang S, Xu G, Zhou J, Ma D (2006) Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells. Apoptosis 11:1789-1800
    • (2006) Apoptosis , vol.11 , pp. 1789-1800
    • Gao, Q.1    Huang, X.2    Tang, D.3    Cao, Y.4    Chen, G.5    Lu, Y.6    Zhuang, L.7    Wang, S.8    Xu, G.9    Zhou, J.10    Ma, D.11
  • 12
    • 57149102928 scopus 로고    scopus 로고
    • Phase i dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors
    • 18955456 10.1200/JCO.2008.16.1547 1:CAS:528:DC%2BD1MXmsVSktg%3D%3D
    • Mross K, Frost A, Steinbild S, Hedbom S, Rentschler J, Kaiser R, Rouyrre N, Trommeshauser D, Hoesl CE, Munzert G (2008) Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors. J Clin Oncol 26:5511-5517
    • (2008) J Clin Oncol , vol.26 , pp. 5511-5517
    • Mross, K.1    Frost, A.2    Steinbild, S.3    Hedbom, S.4    Rentschler, J.5    Kaiser, R.6    Rouyrre, N.7    Trommeshauser, D.8    Hoesl, C.E.9    Munzert, G.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.