메뉴 건너뛰기




Volumn 69, Issue 2, 2013, Pages 151-159

Chemotherapy plus multitargeted antiangiogenic tyrosine kinase inhibitors or chemotherapy alone in advanced NSCLC: A meta-analysis of randomized controlled trials

Author keywords

Chemotherapy; Meta analysis; Multitargeted antiangiogenic TKI; Non small cell lung cancer; RCTs

Indexed keywords

ANTINEOPLASTIC AGENT; AXITINIB; CEDIRANIB; DOCETAXEL; NINTEDANIB; PACLITAXEL; PAZOPANIB; PEMETREXED; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; SUNITINIB; VANDETANIB;

EID: 84873713565     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-012-1333-3     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • 20610543 10.3322/caac.20073
    • Jemal A, Siegel R, Xu J et al (2010) Cancer statistics, 2010. CA Cancer J Clin 60:277-300
    • (2010) CA Cancer J Clin , vol.60 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3
  • 2
    • 34848837026 scopus 로고    scopus 로고
    • Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines
    • 17873159 10.1378/chest.07-1347 1:CAS:528:DC%2BD2sXht1amt7jN
    • Alberg A, Ford J, Samet J (2007) Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines. Chest 132:29S-55S
    • (2007) Chest , vol.132
    • Alberg, A.1    Ford, J.2    Samet, J.3
  • 3
    • 65349124698 scopus 로고    scopus 로고
    • Current treatments for advanced stage non-small cell lung cancer
    • 19349493 10.1513/pats.200809-110LC 1:CAS:528:DC%2BD1MXltlOqtLY%3D
    • Stinchcombe TE, Socinski MA (2009) Current treatments for advanced stage non-small cell lung cancer. Proc Am Thorac Soc 6:233-241
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 233-241
    • Stinchcombe, T.E.1    Socinski, M.A.2
  • 7
    • 44249086425 scopus 로고    scopus 로고
    • Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
    • DOI 10.4065/83.5.584
    • Molina JR, Yang P, Cassivi SD et al (2008) Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 83:584-594 (Pubitemid 351720831)
    • (2008) Mayo Clinic Proceedings , vol.83 , Issue.5 , pp. 584-594
    • Molina, J.R.1    Yang, P.2    Cassivi, S.D.3    Schild, S.E.4    Adjei, A.A.5
  • 10
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial
    • 19027483 10.1016/S0140-6736(08)61758-4 1:CAS:528:DC%2BD1cXhsVWhtbjM
    • Kim ES, Hirsh V, Mok T et al (2008) Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial. Lancet 372:1809-1818
    • (2008) Lancet , vol.372 , pp. 1809-1818
    • Kim, E.S.1    Hirsh, V.2    Mok, T.3
  • 11
    • 67649395763 scopus 로고    scopus 로고
    • Investigational agents in the management of non-small cell lung cancer
    • 19508832 10.1007/s11912-009-0039-x 1:CAS:528:DC%2BC3cXhtFersrzK
    • Pennell NA, Mekhai T (2009) Investigational agents in the management of non-small cell lung cancer. Curr Oncol Rep 11:275-284
    • (2009) Curr Oncol Rep , vol.11 , pp. 275-284
    • Pennell, N.A.1    Mekhai, T.2
  • 12
    • 33745604956 scopus 로고    scopus 로고
    • Interaction between the epidermal growth factor receptor (EGFR) and the vascular endothelial growth factor (VEGF) pathways: A rational approach for multi-target anticancer therapy
    • DOI 10.1093/annonc/mdl962
    • Ciardiello F, Troiani T, Bianco R et al (2006) Interaction between the epidermal growth factor receptor (EGFR) and the vascular endothelial growth factor (VEGF) pathways: A rational approach for multitarget anticancer therapy. Ann Oncol 17:vii109-vii114 (Pubitemid 43985191)
    • (2006) Annals of Oncology , vol.17 , Issue.SUPPL. 7
    • Ciardiello, F.1    Troiani, T.2    Bianco, R.3    Orditura, M.4    Morgillo, F.5    Martinelli, E.6    Morelli, M.P.7    Cascone, T.8    Tortora, G.9
  • 13
    • 66149163097 scopus 로고    scopus 로고
    • Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance
    • 19447865 10.1158/1078-0432.CCR-08-2904 1:CAS:528:DC%2BD1MXmtVKlsr0%3D
    • Naumov GN, Nilsson MB, Cascone T et al (2009) Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clin Cancer Res 15:3484-3494
    • (2009) Clin Cancer Res , vol.15 , pp. 3484-3494
    • Naumov, G.N.1    Nilsson, M.B.2    Cascone, T.3
  • 14
    • 66249135629 scopus 로고    scopus 로고
    • Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC
    • 19357226 10.1634/theoncologist.2008-0276 1:CAS:528:DC%2BD1MXlvFOhtLs%3D
    • Pennell NA, Lynch TJ (2009) Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC. Oncologist 14:399-411
    • (2009) Oncologist , vol.14 , pp. 399-411
    • Pennell, N.A.1    Lynch, T.J.2
  • 15
    • 70349782389 scopus 로고    scopus 로고
    • An overview of small molecule inhibitors of VEGFR signaling
    • 19736552 10.1038/nrclinonc.2009.130 1:CAS:528:DC%2BD1MXhtFyntbbI
    • Ivy SP, Wick JY, Kaufman BM (2009) An overview of small molecule inhibitors of VEGFR signaling. Nat Rev Clin Oncol 6:569-579
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 569-579
    • Ivy, S.P.1    Wick, J.Y.2    Kaufman, B.M.3
  • 16
    • 79953793443 scopus 로고    scopus 로고
    • Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer
    • 21469981 10.3109/07357907.2011.554476 1:CAS:528:DC%2BC3MXksVeiu70%3D
    • Ulahannan SV, Brahmer JR (2011) Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer. Cancer Invest 29(4):325-337
    • (2011) Cancer Invest , vol.29 , Issue.4 , pp. 325-337
    • Ulahannan, S.V.1    Brahmer, J.R.2
  • 17
    • 77954035012 scopus 로고    scopus 로고
    • Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): A double-blind, randomised, phase 3 trial
    • 20570559 10.1016/S1470-2045(10)70132-7 1:CAS:528:DC%2BC3cXotVWqu78%3D
    • Herbst RS, Sun Y, Eberhardt WE et al (2010) Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. Lancet Oncol 11:619-626
    • (2010) Lancet Oncol , vol.11 , pp. 619-626
    • Herbst, R.S.1    Sun, Y.2    Eberhardt, W.E.3
  • 18
    • 79952742483 scopus 로고    scopus 로고
    • Vandetanib plus pemetrexed for the second-line treatment of advanced non-small-cell lung cancer: A randomized, double-blind phase III trial
    • 21282537 10.1200/JCO.2010.29.5717
    • de Boer RH, Arrieta O, Yang CH et al (2011) Vandetanib plus pemetrexed for the second-line treatment of advanced non-small-cell lung cancer: a randomized, double-blind phase III trial. J Clin Oncol 29:1067-1074
    • (2011) J Clin Oncol , vol.29 , pp. 1067-1074
    • De Boer, R.H.1    Arrieta, O.2    Yang, C.H.3
  • 19
    • 56749102822 scopus 로고    scopus 로고
    • Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer
    • 18936474 10.1200/JCO.2008.17.3138 1:CAS:528:DC%2BD1MXhslClsg%3D%3D
    • Heymach JV, Paz-Ares L, De Braud F et al (2008) Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol 26:5407-5415
    • (2008) J Clin Oncol , vol.26 , pp. 5407-5415
    • Heymach, J.V.1    Paz-Ares, L.2    De Braud, F.3
  • 21
    • 77951639655 scopus 로고    scopus 로고
    • Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer
    • 20212250 10.1200/JCO.2009.26.1321 1:CAS:528:DC%2BC3cXmsFyitL0%3D
    • Scagliotti G, Novello S, von PJ et al (2010) Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer. J Clin Oncol 28:1835-1842
    • (2010) J Clin Oncol , vol.28 , pp. 1835-1842
    • Scagliotti, G.1    Novello, S.2    Von, P.J.3
  • 22
    • 73949092851 scopus 로고    scopus 로고
    • Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study
    • 19917841 10.1200/JCO.2009.22.9427 1:CAS:528:DC%2BC3cXhtF2ku7Y%3D
    • Goss GD, Arnold A, Shepherd FA et al (2010) Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study. J Clin Oncol 28:49-55
    • (2010) J Clin Oncol , vol.28 , pp. 49-55
    • Goss, G.D.1    Arnold, A.2    Shepherd, F.A.3
  • 24
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M et al (1997) Bias in meta-analysis detected by a simple, graphical test. Br Med J 315:629-634 (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 25
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • DOI 10.1159/000088478
    • Carmeliet P (2005) VEGF as a key mediator of angiogenesis in cancer. Oncology 69[Suppl 3]:4-10 (Pubitemid 41680947)
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 4-10
    • Carmeliet, P.1
  • 26
    • 31344474845 scopus 로고    scopus 로고
    • Angiogenesis in non-small cell lung cancer: The prognostic impact of neoangiogenesis and the cytokines VEGF and bFGF in tumours and blood
    • DOI 10.1016/j.lungcan.2005.09.005, PII S0169500205004988
    • Bremnes RM, Camps C, Sirera R (2006) Angiogenesis in non-small cell lung cancer: the prognostic impact of neo angiogenesis and the cytokines VEGF and bFGF in tumors and blood. Lung Cancer 51:143-158 (Pubitemid 43144358)
    • (2006) Lung Cancer , vol.51 , Issue.2 , pp. 143-158
    • Bremnes, R.M.1    Camps, C.2    Sirera, R.3
  • 27
    • 76749101884 scopus 로고    scopus 로고
    • Antiangiogenic therapy in lung cancer: Focus on vascular endothelial growth factor pathway
    • 10.1258/ebm.2009.009191
    • Grzegorz Korpanty G, Smyth E, Sullivan LA (2010) Antiangiogenic therapy in lung cancer: focus on vascular endothelial growth factor pathway. Exp Biol Med 235:3-9
    • (2010) Exp Biol Med , vol.235 , pp. 3-9
    • Grzegorz Korpanty, G.1    Smyth, E.2    Sullivan, L.A.3
  • 29
    • 44649149619 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor cediranib for non-small cell lung cancer and other thoracic malignancies
    • DOI 10.1097/JTO.0b013e318174e910, PII 0124389420080600100006
    • Nikolinakos P, Heymach JV (2008) The tyrosine kinase inhibitor cediranib for non-small cell lung cancer and other thoracic malignancies. JThorac Oncol 3[6 Suppl 2]:S131-S134 (Pubitemid 351786743)
    • (2008) Journal of Thoracic Oncology , vol.3 , Issue.6 SUPPL. 2
    • Nikolinakos, P.1    Heymach, J.V.2
  • 30
    • 34249686689 scopus 로고    scopus 로고
    • Toxicities of antiangiogenic therapy in non-small-cell lung cancer
    • 17239287 10.3816/CLC.2006.s.010 1:CAS:528:DC%2BD2sXhs1Sisbo%3D
    • Herbst RS (2006) Toxicities of antiangiogenic therapy in non-small-cell lung cancer. Clin Lung Cancer 8[Suppl 1]:S23-S30
    • (2006) Clin Lung Cancer , vol.8 , Issue.SUPPL. 1
    • Herbst, R.S.1
  • 31
    • 62549108221 scopus 로고    scopus 로고
    • Toxicity of targeted therapy in non-small-cell lung cancer management
    • 19289369 10.3816/CLC.2009.n.004 1:CAS:528:DC%2BD1MXjslalu70%3D
    • Ricciardi S, Tomao S, de Marinis F (2009) Toxicity of targeted therapy in non-small-cell lung cancer management. Clin Lung Cancer 10:28-35
    • (2009) Clin Lung Cancer , vol.10 , pp. 28-35
    • Ricciardi, S.1    Tomao, S.2    De Marinis, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.