Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury

Respiratory Research

Volumn 14, Issue 1, 2013, Pages

  Glasser, Stephan W ^a   Senft, Albert P ^b   Maxfield, Melissa D ^a   Ruetschilling, Teah L ^b   Baatz, John E ^c   Page, Kristen ^a   Korfhagen, Thomas R ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Clara cell secretory protein (CCSP); Interstitial lung disease; Lung inflammation; Respiratory syncytial virus; Surfactant protein C; Type II cells

Indexed keywords

DOXYCYCLINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PROTEIN ANTIBODY; SURFACTANT PROTEIN C; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE RESPONSE; GENE EXPRESSION; GENE REPLACEMENT THERAPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; LAVAGE; LUNG ALVEOLUS CELL TYPE 2; LUNG HOMOGENATE; LUNG INJURY; MOUSE; NEUTROPHIL; NONHUMAN; PARAMYXOVIRUS INFECTION; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOFT TISSUE INFLAMMATION; TRANSGENE; WESTERN BLOTTING; 129 MOUSE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DOWN REGULATION; GENETICS; METABOLISM; METHODOLOGY; RESPIRATORY SYNCYTIAL VIRUS INFECTION; TRANSGENIC MOUSE; VIRUS LOAD; HUMAN RESPIRATORY SYNCYTIAL VIRUS; PROCEDURES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS;

ANIMALS; CELLS, CULTURED; DOWN-REGULATION; LUNG INJURY; MICE; MICE, 129 STRAIN; MICE, TRANSGENIC; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; VIRAL LOAD;

EID: 84873701025     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-14-19     Document Type: Article

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