Human plasma-derived polymeric IgA and IgM antibodies associate with secretory component to yield biologically active secretory-like antibodies

Journal of Biological Chemistry

Volumn 288, Issue 6, 2013, Pages 4085-4094

  Longet, Stéphanie ^a   Miled, Sarah ^a   Lötscher, Marius ^b   Miescher, Sylvia M ^b   Zuercher, Adrian W ^b   Corthésy, Blaise ^a,b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b CSL Behring AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULES; PLASMA (HUMAN); PURIFICATION;

AUTOIMMUNE DISEASE; BINDING CAPACITIES; CLINICAL CONDITIONS; FUNCTIONAL CHARACTERISTICS; INDUCED DAMAGE; MODEL PATHOGEN; SHIGELLA FLEXNERI; THERAPEUTIC APPLICATION;

ANTIBODIES;

IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; INTESTINAL PROTEASE; INTESTINE ENZYME; POLYMERIC IMMUNOGLOBULIN A; POLYMERIC IMMUNOGLOBULIN M; PROTEINASE; RECOMBINANT PROTEIN; SECRETORY COMPONENT; SECRETORY IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ARTICLE; BACTERIAL IMMUNITY; BACTERIUM NEUTRALIZATION; BINDING AFFINITY; CELL DAMAGE; CELL POLARITY; CELL STRAIN CACO 2; COLOSTRUM; COMPARATIVE STUDY; COVALENT BOND; HUMAN; HUMAN CELL; IMMUNOGLOBULIN STRUCTURE; IN VITRO STUDY; MONOLAYER CULTURE; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN POLYMERIZATION; PROTEIN PURIFICATION; SHIGELLA FLEXNERI; STOICHIOMETRY;

EID: 84873661323     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.410811     Document Type: Article

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