Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-β: Prodromal Alzheimer's disease?

Journal of Alzheimer's Disease

Volumn 33, Issue 4, 2013, Pages 1167-1176

  Lim, Yen Ying ^a   Ellis, Kathryn A ^a,b   Harrington, Karra ^a   Pietrzak, Robert H ^c   Gale, Joanne ^d   Ames, David ^a,b   Bush, Ashley I ^a   Darby, David ^a   Martins, Ralph N ^e   Masters, Colin L ^a   Rowe, Christopher C ^a,f   Savage, Greg ^g   Szoeke, Cassandra ^a,b   Villemagne, Victor L ^a,f   Maruff, Paul ^a,d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b NATIONAL AGEING RESEARCH INSTITUTE   (Australia)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Yale University School of Medicine ^*  (Australia)

^e EDITH COWAN UNIVERSITY   (Australia)

^f AUSTIN HEALTH   (Australia)

^g MACQUARIE UNIVERSITY   (Australia)

Author keywords

Alzheimer's disease; amyloid ; cognitive change; cognitive neuropsychology; mild cognitive impairment

Indexed keywords

AMYLOID BETA PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; AMNESIA; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; EPISODIC MEMORY; FEMALE; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; INTELLIGENCE QUOTIENT; MAGNITUDE ESTIMATION METHOD; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; VERBAL MEMORY; VISUAL MEMORY; WORKING MEMORY;

EID: 84873657034     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-121771     Document Type: Article

References (52)

1. Okello A, Koivunen J, Edison P, Archer HA, Turkheimer FE, Nagren K, Bullock R,Walker Z, Kennedy A, Fox NC, Rossor MN, Rinne JO, Brooks DJ (2009) Conversion of amyloid positive and negative MCI to AD over 3 years: An 11C-PIB PET study. Neurology 73, 754-760
2. Villemagne VL, Pike KE, Ch́etelat G, Ellis KA, Mulligan RS, Bourgeat P, Ackermann U, Jones G, Szoeke C, Salvado O, Martins R, O'Keefe G, Mathis CA, Klunk WE, Ames D, Masters CL, Rowe CC (2011) Longitudinal assessment ofA and cognition in aging and Alzheimer disease. Ann Neurol 69, 181-192
3. Landau SM, Harvey D, Madison CM, Reiman EM, Foster NL, Aisen PS, Petersen RC, Shaw LM, Trojanowski JQ, Jack CR, Weiner MW, Jagust WJ, Initiative AsDN (2010) Comparing predictors of conversion and decline in mild cognitive impairment. Neurology 75, 230-238
4. Koivunen J, Scheinin N,Virta JR, Aalto S,Vahlberg T, Nagren K, Helin S, Parkkola R,Viitanen M, Rinne JO (2011) Amyloid PET imaging in patients with mild cognitive impairment: A 2-year follow-up study. Neurology 76, 1085-1090
5. Albert MS, Blacker D, Moss MB, Tanzi R, McArdle JJ (2007) Longitudinal change in cognitive performance among individuals with mild cognitive impairment. Neuropsychology 21, 158-169
6. Howieson DB, Carlson MC, Moore MM, Wasserman D, Abendroth CD, Payne-Murphy J, Kaye JA (2008) Trajectory of mild cognitive impairment onset. J Int Neuropsych Soc 14, 192-198
7. Hansson O, ZetterbergH, Buchhave P, Andreasson U, Londos E, Minthon L, Blennow K (2007) Prediction of Alzheimer's disease using the CSF A42/A40 ratio in patients with mild cognitive impairment. Dement Geriatr Cogn 23, 316-320
8. Doraiswamy PM, Sperling RA, Coleman RE, Johnson KA, Reiman EM, Davis MD, Grundman M, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Clark CM, Joshi AD, Mintun MA, Skovronsky DM, Pontecorvo MJ, Group A-AS (2012) Amyloid-B assessed by florbetapir F 18 PET and 18-month cognitive decline. Neurology 79, 1636-1644
9. Dubois B, Feldman HH, Jacova C, DeKosky ST, Barberger-Gateau P, Cummings J, Delacourte A, Galasko D, Gauthier S, Jicha G,Meguro K, O'Brien J, Pasquier F, Robert P, Rossor M, Salloway S, Stern Y, Visser PJ, Scheltens P (2007) Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDS -ADRDA criteria. Lancet Neurol 6, 734-746
10. Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH (2011) The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging and Alzheimer's Association workgroup. Alzheimers Dement 7, 270-279
11. Darby D, Brodtmann A, Woodward M, Budge M, Maruff P (2011) Using cognitive decline in novel trial designs for primary prevention and early disease-modifying therapy trials of Alzheimer's disease. Int Psychogeriatr 1-10
12. Albert MS (2011) Changes in cognition. Neurobiol Aging 32, S58-S63
13. Johnsen S, Hughes S, Bullock R, Hindmarch I (2003) Prediction of the rate of decline in cognitive function in Alzheimer's disease: A model based on simple demographic data and widely used rating scales. Dement Geriatr Cogn 16, 276-282
14. Nordlund A, Rolstad S, Klang O, Lind K, Pedersen M, Blennow K, Edman A, Hansen S, Wallin A (2008) Episodic memory and speed/attention deficits are associated with Alzheimer-Typical CSF abnormalities in MCI. J Int Neuropsych Soc 14, 582-590
15. Small GW, Siddarth P, Kepe V, Ercoli LM, Burggren AC, Bookheimer SY, Miller KJ, Kim J, Lavretsky H, Huang SC, Barrio JR (2012) Prediction of cognitive decline by positron emission tomography of brain amyloid and tau. Arch Neurol 69, 215-222
16. Grill JD, Di LJ, Lu PH, Lee C, Ringman J, Apostolova LG, Chow N, Kohannim O, Cummings JL, Thompson PM, Elashoff D, Initiative AsDN (2012) Estimating sample sizes for predementia Alzheimer's trials based on the Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging 34, 62-72
17. Ewers M, Insel P, Jagust WJ, Shaw L, Trojanowski JQ, Aisen P, Petersen RC, Schuff N,Weiner MF, Initiative AsDN (2012) CSF biomarker and PIB-PET-derived beta-Amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects. Cereb Cortex 22, 1993-2004
18. Pike KE, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, Mathis CA, Klunk WE, Masters CL, Rowe CC (2007) -Amyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease. Brain 130, 2837-2844
19. Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal L, Study AsDC (2005)Vitamin E and Donepezil for the treatment of mild cognitive impairment. New Engl J Med 352, 2379-2388
20. Dubois B, Albert ML (2004) Amnestic MCI or prodromal Alzheimer's disease? Lancet Neurol 3, 246-248
21. Lim YY, Ellis KA, Pietrzak RH, Ames D, Darby D, Harrington K, Martins RN, Masters CL, Rowe C, Savage G, Szoeke C,Villemagne VL, Maruff P, AIBLRG(2012) Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults. Neurology 79, 1645-1652
22. Ellis KA, Bush AI, Darby D, De Fazio D, Foster J, Hudson P, Lautenschlager NT, Lenzo N, Martins RN,Maruff P,Masters C, Milner A, Pike K, Rowe C, Savage G, Szoeke C, Taddei K, VillemagneV,Woodward M,AmesD, GroupTAR(2009) The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: Methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. Int Psychogeriatr 21, 672-687
23. Rowe CC, Ellis KA, Rimajova M, Bourgeat P, Pike KE, Jones G, Fripp J, Tochon-Danguy H, Morandeau L, O'Keefe G, Price R, Raniga P, Robins P, Acosta O, Lenzo N, Szoeke C, Salvado O, Head R, Martins RM, Ames CL, Villemagne D, V (2010) Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging 31, 1275-1283
24. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E (1999) Mild cognitive impairment: Clinical characterization and outcome. Arch Neurol 56, 303-308
25. Winblad B, Palmer K, Kivipelto M, Jelic V, Fratiglioni L, Wahlund LO, Nordberg A, Bäckman L, Albert M, Almkvist O, Arai H, Basun H, Blennow K, de Leon M, DeCarli C, Erkinjuntti T, Giacobini E, Graff C, Hardy J, Jack C, Jorm A, Ritchie K, van Duijn C, Visser P, Petersen RC (2004) Mild cognitive impairment -beyond controversies, towards a consensus: Report of the International Working Group on mild cognitive impairment. J Intern Med 256, 240-246
26. Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup. Alzheimers Dement 7, 280-292
27. Villemagne VL, Pike KE, Darby D, Maruff P, Savage G, Ng S, Ackermann U, Cowie TF, Currie J, Chan SG, Jones G, Tochon-Danguy H, O'Keefe G, Masters CL, Rowe CC (2008) A deposits in older non-demented individuals with cogni tive decline are indicative of preclinical Alzheimer's disease. Neuropsychologia 46, 1688-1697
28. Pike KE, Ellis KA, Villemagne VL, Good NM, Chetelat G, Ames D, SzoekeC,Laws SM,Verdile G, Martins RN, Masters C, RoweCC(2011) Cognition and beta-Amyloid in preclinical Alzheimer's disease: Data from the AIBL study. Neuropsychologia 49, 2384-2390
29. Lim YY, Ellis KA, Harrington K, Ames D, Martins RN, Masters CL, Rowe C, Savage G, Szoeke C, Darby D, Maruff P, AIBL, RG (2012) Use of the CogState Brief Battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarker and Lifestyle (AIBL) study. J Clin Exp Neuropsyc 34, 345-358
30. Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state:Apractical method for grading cognitive state of patients for the clinician. J Psychiat Res 12, 189-198
31. Morris JC (1983) The Clinical Dementia Rating (CDR): Current version and scoring rules. Neurology 43, 2412-2414
32. Wechsler D (2001) Wechsler Test of Adult Reading: Examiner's manual, The Psychological Corporation, San Antonio, T.X.
33. Snaith RP, Zigmond AS (1986) The hospital anxiety and depression scale. Brit Med 292, 344
34. Fredrickson J, Maruff P, Woodward M, Moore L, Fredrickson A, Sach J, Darby D (2010) Evaluation of the usability of a brief computerized cognitive screening test in older people for epidemiological studies. Neuroepidemiology 34, 65-75
35. Hammers D, Spurgeon E, Ryan K, Persad C, Heidebrink J, Barbas N, Albin R, Frey K, Darby D, Giordani B (2011) Reliability of repeated cognitive assessment of dementia using a brief computerized battery. Am J Alzheimers Dis 26, 326-333
36. Delis DC, Kramer JH, Kaplan E, Ober BA (2000) California Verbal Learning Test-Second Edition (CVLT-II), The Psychological Corporation, San Antonio, T.X.
37. Kantarci K, Lowe V, Przybelski SA, Weigand SD, Senjem ML, Ivnik RJ, Preboske GM, Roberts R, Geda YE, Boeve BF, Knopman DS, Petersen RC, Jack CR (2012) APOE modifies the association between A load and cognition in cognitively normal older adults. Neurology 78, 232-240
38. Jack CR, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, Knopman DS, Boeve BF, Klunk WE, Mathis CA, Petersen RC (2008) 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain 131, 665-680
39. Cohen J (1992) A power primer. Psychol Bull 112, 155-159
40. Lindsey JK (1997) Applying generalized linear models, Springer, New York
41. Hendrix SB (2011) Requiring an amyloid-1-42 biomarker may improve the efficiency of a study, and simulations may help in planning studies. Alzheimers Res Ther 3, 10
42. Jackson O, Schacter DL (2004) Encoding activity in anterior medial temporal lobe supports subsequent associative recognition. NeuroImage 21, 456-462
43. Eichenbaum H, Yonelinas AR, Ranganath C (2007) The medial temporal lobe and recognition memory. Annu Rev Neurosci 30, 123-152
44. Harel BT, Darby D, Pietrzak RH, Ellis KA, Snyder PJ, Maruff P (2011) Examining the nature of impairment in visual paired associate learning in amnestic mild cognitive impairment. Neuropsychology 25, 752-762
45. O'Donnell J, Pietrzak RH, Ellis KA, Snyder PJ, Maruff P (2011) Understanding failure of visual paired associate learning in amnestic mild cognitive impairment. J Clin Exp Neuropsyc 33, 1069-1078
46. Braak H, Braak E (1991) Neuropathological staging of Alzheimer-related changes. Neuropathologica 82, 239-259
47. Knopman DS, Parisi JE, Salviati A, Floriach-Robert M, Boeve BF, Ivnik RJ, Smith GE, Dickson DW, Johnson KA, Petersen LE, McDonald WC, Braak H, Petersen RC (2003) Neuropathology of cognitively normal elderly. J Neuropath Exp Neur 62, 1087-1095
48. Wagner M, Wolf S, Reischies FM, Daerr M, Wolfsgruber S, Jessen F, Popp J, Maier W, Hüll M, Frölich L, Hampel H, Perneczky R, Peters O, Jahn H, Luckhaus C, Gertz HJ, Schröder J, Pantel J, Lewczuk P, Kornhuber J, Wiltfang J (2012) Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease. Neurology 78, 379-386
49. Dickerson BC, Sperling RA (2008) Functional abnormalities of the medial temporal lobe memory system in mild cognitive impairment and Alzheimer's disease: Insights from functional MRI studies. Neuropsychologia 46, 1624-1635
50. Jack CR, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, Shiung MM, Gunter JL, Boeve BF, Kemp BJ, Weiner MW, Petersen RC, Initiative TAsDN (2009) Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease. Brain 132, 1355-1365
51. Kazis LE, Anderson JJ, Meenan RF (1989) Effect sizes for interpreting changes in health status. Med Care 27, 178-189
52. Morris JC, Roe CM, Xiong CJ, Fagan AM, Goate AM, Holtzman DM, Mintun MA (2010) APOE predicts A but not tau Alzheimer's pathology in cognitively normal aging. Ann Neurol 67, 122-131